A high-throughput drug combination screen of targeted small molecule inhibitors in cancer cell lines.

abstract：:This paper describes the methodology of an ongoing project of constructing an East Asian climate database REACHES based on Chinese historical documents. The record source is Compendium of Meteorological Records of China in the Last 3000 Years which collects meteorology and climate related records from mainly official ...

journal_title：Scientific data

authors： Wang PK,Lin KE,Liao YC,Liao HM,Lin YS,Hsu CT,Hsu SM,Wan CW,Lee SY,Fan IC,Tan PH,Ting TT

更新日期：2018-12-18 00:00:00

abstract：:Today's scientific data are primarily stored and accessed via centralized Web-based infrastructure. Centralization has advantages but also carries risks such as link rot and content drift, which can hinder scientific progress. It is time to ask whether traditional, centralized Web architecture aligns with scholarly pr...

journal_title：Scientific data

authors： Robinson DC,Hand JA,Madsen MB,McKelvey KR

更新日期：2018-10-23 00:00:00

abstract：:Functional trait databases are emerging as crucial tools for a wide range of ecological studies across the world. Here, we provide a database of functional traits for vascular plant species of the Mediterranean Basin. The database includes 25,764 individual records of 44 traits from 2,457 plant taxa distributed in 119...

journal_title：Scientific data

authors： Tavşanoğlu Ç,Pausas JG

更新日期：2018-07-10 00:00:00

abstract：:East Africa is a drought prone, food and water insecure region with a highly variable climate. This complexity makes rainfall estimation challenging, and this challenge is compounded by low rain gauge densities and inhomogeneous monitoring networks. The dearth of observations is particularly problematic over the past ...

journal_title：Scientific data

authors： Funk C,Nicholson SE,Landsfeld M,Klotter D,Peterson P,Harrison L

更新日期：2015-09-29 00:00:00

abstract：:The use of hydrogen (H2) as a substitute for fossil fuel, which accounts for the majority of the world's energy, is environmentally the most benign option for the reduction of CO2 emissions. This will require gigawatt-scale storage systems and as such, H2 storage in porous rocks in the subsurface will be required. Acc...

journal_title：Scientific data

authors： Hassanpouryouzband A,Joonaki E,Edlmann K,Heinemann N,Yang J

更新日期：2020-07-09 00:00:00

abstract：:Brain atlases that encompass detailed anatomical or physiological features are instrumental in the research and surgical planning of various neurological conditions. Magnetic resonance imaging (MRI) has played important roles in neuro-image analysis while histological data remain crucial as a gold standard to guide an...

journal_title：Scientific data

authors： Xiao Y,Lau JC,Anderson T,DeKraker J,Collins DL,Peters T,Khan AR

更新日期：2019-10-17 00:00:00

abstract：:Direct-infusion mass spectrometry (DIMS) metabolomics is an important approach for characterising molecular responses of organisms to disease, drugs and the environment. Increasingly large-scale metabolomics studies are being conducted, necessitating improvements in both bioanalytical and computational workflows to ma...

journal_title：Scientific data

authors： Kirwan JA,Weber RJ,Broadhurst DI,Viant MR

更新日期：2014-06-10 00:00:00

abstract：:Surveys for more than 9,500 households were conducted in the growing seasons 2002/2003 or 2003/2004 in eleven African countries: Burkina Faso, Cameroon, Ghana, Niger and Senegal in western Africa; Egypt in northern Africa; Ethiopia and Kenya in eastern Africa; South Africa, Zambia and Zimbabwe in southern Africa. Hous...

journal_title：Scientific data

authors： Waha K,Zipf B,Kurukulasuriya P,Hassan RM

更新日期：2016-05-24 00:00:00

abstract：:Neural microarchitecture is heterogeneous, varying both across and within brain regions. The consistent identification of regions of interest is one of the most critical aspects in examining neurocircuitry, as these structures serve as the vital landmarks with which to map brain pathways. Access to continuous, three-d...

journal_title：Scientific data

authors： Prasad JA,Balwani AH,Johnson EC,Miano JD,Sampathkumar V,De Andrade V,Fezzaa K,Du M,Vescovi R,Jacobsen C,Kording KP,Gürsoy D,Gray Roncal W,Kasthuri N,Dyer EL

更新日期：2020-10-20 00:00:00

abstract：:One important use of genome-wide transcriptional profiles is to identify relationships between transcription levels and patient outcomes. These translational insights can guide the development of biomarkers for clinical application. Data from thousands of translational-biomarker studies have been deposited in public r...

journal_title：Scientific data

authors： Golightly NP,Bell A,Bischoff AI,Hollingsworth PD,Piccolo SR

更新日期：2018-04-17 00:00:00

abstract：:Accurately characterizing land surface changes with Earth Observation requires geo-located ground truth. In the European Union (EU), a tri-annual surveyed sample of land cover and land use has been collected since 2006 under the Land Use/Cover Area frame Survey (LUCAS). A total of 1351293 observations at 651780 unique...

journal_title：Scientific data

authors： d'Andrimont R,Yordanov M,Martinez-Sanchez L,Eiselt B,Palmieri A,Dominici P,Gallego J,Reuter HI,Joebges C,Lemoine G,van der Velde M

更新日期：2020-10-16 00:00:00

abstract：:Eicosanoids comprise a class of bioactive lipids derived from a unique group of essential fatty acids that mediate a variety of important physiological functions. Owing to the structural diversity of these lipids, their analysis in biological samples is often a major challenge. Advancements in mass spectrometric have ...

journal_title：Scientific data

authors： Sorgi CA,Peti APF,Petta T,Meirelles AFG,Fontanari C,Moraes LAB,Faccioli LH

更新日期：2018-08-21 00:00:00

abstract：:Long-term datasets of number and size of lakes over the Tibetan Plateau (TP) are among the most critical components for better understanding the interactions among the cryosphere, hydrosphere, and atmosphere at regional and global scales. Due to the harsh environment and the scarcity of data over the TP, data accumula...

journal_title：Scientific data

authors： Wan W,Long D,Hong Y,Ma Y,Yuan Y,Xiao P,Duan H,Han Z,Gu X

更新日期：2016-06-21 00:00:00

abstract：:Neuroblastoma cell lines are an important and cost-effective model used to study oncogenic drivers of the disease. While many of these cell lines have been previously characterized with SNP, methylation, and/or mRNA expression microarrays, there has not been an effort to comprehensively sequence these cell lines. Here...

journal_title：Scientific data

authors： Harenza JL,Diamond MA,Adams RN,Song MM,Davidson HL,Hart LS,Dent MH,Fortina P,Reynolds CP,Maris JM

更新日期：2017-03-28 00:00:00

abstract：:Connective tissues such as tendon, ligament and skin are biological fibre composites comprising collagen fibrils reinforcing the weak proteoglycan-rich ground substance in extracellular matrix (ECM). One of the hallmarks of ageing of connective tissues is the progressive and irreversible change in the tissue mechanica...

journal_title：Scientific data

authors： Goh KL,Holmes DF,Lu YH,Kadler KE,Purslow PP

更新日期：2018-07-24 00:00:00

abstract：:The insights that historical evidence of human presence and man-made documents provide are unique. For example, using historical data may be critical to adequately understand the ecological requirements of species. However, historical information about freshwater species distribution remains largely a knowledge gap. I...

journal_title：Scientific data

authors： Duarte G,Moreira M,Branco P,da Costa L,Ferreira MT,Segurado P

更新日期：2018-08-14 00:00:00

abstract：:The immune response to major trauma has been analysed mainly within post-hospital admission settings where the inflammatory response is already underway and the early drivers of clinical outcome cannot be readily determined. Thus, there is a need to better understand the immediate immune response to injury and how thi...

journal_title：Scientific data

authors： Bravo-Merodio L,Acharjee A,Hazeldine J,Bentley C,Foster M,Gkoutos GV,Lord JM

更新日期：2019-12-19 00:00:00

abstract：:In Eco-Metabolomics interactions are studied of non-model organisms in their natural environment and relations are made between biochemistry and ecological function. Current challenges when processing such metabolomics data involve complex experiment designs which are often carried out in large field campaigns involvi...

journal_title：Scientific data

authors： Peters K,Gorzolka K,Bruelheide H,Neumann S

更新日期：2018-08-28 00:00:00

abstract：:Medical augmented reality (AR) is an increasingly important topic in many medical fields. AR enables x-ray vision to see through real world objects. In medicine, this offers pre-, intra- or post-interventional visualization of "hidden" structures. In contrast to a classical monitor view, AR applications provide visual...

journal_title：Scientific data

authors： Gsaxner C,Wallner J,Chen X,Zemann W,Egger J

更新日期：2019-12-09 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific data

authors： Schweiker M,Abdul-Zahra A,André M,Al-Atrash F,Al-Khatri H,Alprianti RR,Alsaad H,Amin R,Ampatzi E,Arsano AY,Azadeh M,Azar E,Bahareh B,Batagarawa A,Becker S,Buonocore C,Cao B,Choi JH,Chun C,Daanen H,Damiati SA,Dan

更新日期：2020-01-06 00:00:00

abstract：:The London Planetree (Platanus acerifolia) are present throughout the world. The tree is considered a greening plant and is commonly planted in streets, parks, and courtyards. The Sycamore lace bug (Corythucha ciliata) is a serious pest of this tree. To determine the molecular mechanism behind the interaction between ...

journal_title：Scientific data

authors： Li F,Wu C,Gao M,Jiao M,Qu C,Gonzalez-Uriarte A,Luo C

更新日期：2019-07-22 00:00:00

abstract：:While the GRACE (Gravity Recovery and Climate Experiment) satellite mission is of great significance in understanding various branches of Earth sciences, the quality of GRACE monthly products can be unsatisfactory due to strong longitudinal stripe-pattern errors and other flaws. Based on corrected GRACE Mascon (mass c...

journal_title：Scientific data

authors： Chen W,Luo J,Ray J,Yu N,Li JC

更新日期：2019-10-23 00:00:00

abstract：:In order to map global disease risk, a geographic database of human Crimean-Congo haemorrhagic fever virus (CCHFV) occurrence was produced by surveying peer-reviewed literature and case reports, as well as informal online sources. Here we present this database, comprising occurrence data linked to geographic point or ...

journal_title：Scientific data

authors： Messina JP,Pigott DM,Duda KA,Brownstein JS,Myers MF,George DB,Hay SI

更新日期：2015-04-14 00:00:00

abstract：:We introduce and make openly accessible a comprehensive, multivariate time series (MVTS) dataset extracted from solar photospheric vector magnetograms in Spaceweather HMI Active Region Patch (SHARP) series. Our dataset also includes a cross-checked NOAA solar flare catalog that immediately facilitates solar flare pred...

journal_title：Scientific data

authors： Angryk RA,Martens PC,Aydin B,Kempton D,Mahajan SS,Basodi S,Ahmadzadeh A,Cai X,Filali Boubrahimi S,Hamdi SM,Schuh MA,Georgoulis MK

更新日期：2020-07-10 00:00:00

abstract：:The silkmoth chorion was studied extensively by F.C. Kafatos' group for almost 40 years. However, the complete structure of the chorion locus was not obtained in the genome sequence of Bombyx mori published in 2008 due to repetitive sequences, resulting in gaps and an incomplete view of the locus. To obtain the comple...

journal_title：Scientific data

authors： Chen Z,Nohata J,Guo H,Li S,Liu J,Guo Y,Yamamoto K,Kadono-Okuda K,Liu C,Arunkumar KP,Nagaraju J,Zhang Y,Liu S,Labropoulou V,Swevers L,Tsitoura P,Iatrou K,Gopinathan KP,Goldsmith MR,Xia Q,Mita K

更新日期：2015-11-10 00:00:00

abstract：:As a World Health Organization Research and Development Blueprint priority pathogen, there is a need to better understand the geographic distribution of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and its potential to infect mammals and humans. This database documents cases of MERS-CoV globally, with speci...

journal_title：Scientific data

authors： Ramshaw RE,Letourneau ID,Hong AY,Hon J,Morgan JD,Osborne JCP,Shirude S,Van Kerkhove MD,Hay SI,Pigott DM

更新日期：2019-12-13 00:00:00

abstract：:Ataxin-1 mutation, arising from a polyglutamine (polyQ) tract expansion, is the underlying genetic cause of the late-onset neurodegenerative disease Spinocerebellar ataxia type 1 (SCA1). To identify protein partners of polyQ-ataxin-1 in neuronal cells under control or stress conditions, here we report our complementar...

journal_title：Scientific data

authors： Zhang S,Williamson NA,Bogoyevitch MA

更新日期：2018-11-20 00:00:00

abstract：:Studies of chimpanzee vocal communication provide valuable insights into the evolution of communication in complex societies, and also comparative data for understanding the evolution of human language. One particularly valuable dataset of recordings from free-living chimpanzees was collected by Frans X. Plooij and th...

journal_title：Scientific data

authors： Plooij FX,van de Rijt-Plooij H,Fischer M,Wilson ML,Pusey A

更新日期：2015-05-26 00:00:00

abstract：:This article presents datasets prepared with the aim of helping the evaluation of geospatial matching methods for vector data. These datasets were built up from mapping data produced by official Spanish mapping agencies. The testbed supplied encompasses the three geometry types: point, line and area. Initial datasets ...

journal_title：Scientific data

authors： Xavier EMA,Ariza-López FJ,Ureña-Cámara MA

更新日期：2017-12-05 00:00:00

abstract：:We present a test-retest dataset for evaluation of long-term reliability of measures from structural and resting-state functional magnetic resonance imaging (sMRI and rfMRI) scans. The repeated scan dataset was collected from 61 healthy adults in two sessions using highly similar imaging parameters at an interval of 1...

journal_title：Scientific data

authors： Huang L,Huang T,Zhen Z,Liu J

更新日期：2016-03-15 00:00:00