Abstract:
BACKGROUND:Takayasu arteritis (TA) is a rare large-vessel arteritis that primarily affects the aorta and its major branches. The aim of this study was to describe the value of high frequency ultrasound for monitoring of inflammatory activity. METHODS:Twenty-five patients, range 11-71 years, diagnosed with TA were investigated with duplex ultrasound (DUS) including follow-up studies. Twenty-five healthy controls were also investigated. Nine patients had newly diagnosed active TA. Sixteen patients had stable/inactive disease at baseline DUS, and TA was diagnosed median 4·5 years previously. Intima-media thickness (IMT), vessel and lumen diameter were measured in the carotid arteries, central neck arteries and the aortic arch. The vessel walls were studied qualitatively. The Takayasu ultrasound index was created for inflammatory activity scoring. RESULTS:Intima-media thickness in common carotid artery (CCA) was (median and 25-75 percentile parenthetic) 2·3 mm (1·7-2·9) in clinically active TA, 1·2 mm (1·1-1·6) in clinically stable TA (P<0·001) and 0·5 mm (0·5-0·6) in healthy controls (P<0·001). Clinically active TA had prominent increase in IMT and/or increased vessel diameter, and/or intramural arteries, and/or hypoechogenic areas interpreted as oedema in the vessel wall. TA in clinical remission was characterized by increased IMT with medium to high echogenicity with or without fibrotic stripes. The Takayasu ultrasound index was higher in patients with active disease versus treated disease, 2·55 (1·60-3·05) versus 1·30 (1·00-1·58), (P = 0·003). CONCLUSION:DUS is an excellent tool to monitor inflammatory changes in the vessel wall in TA. Further DUS studies in larger patient populations are warranted.
journal_name
Clin Physiol Funct Imagingjournal_title
Clinical physiology and functional imagingauthors
Svensson C,Eriksson P,Zachrisson Hdoi
10.1111/cpf.12601subject
Has Abstractpub_date
2020-01-01 00:00:00pages
37-45issue
1eissn
1475-0961issn
1475-097Xjournal_volume
40pub_type
杂志文章abstract::During recent years, the radial movement of the arterial wall has been extensively studied, and measurements of the radial movement are now an important tool in cardiovascular research for characterizing the mechanical properties of the arterial wall. In contrast, the longitudinal movement of vessels has gained little...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1046/j.1475-097x.2003.00504.x
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:Delayed enhancement magnetic resonance imaging depicts scar in the left ventricle which can be quantitatively measured. Manual segmentation and scar determination is time consuming. The purpose of this study was to evaluate a software for infarct quantification, to compare with manual scar determination, and...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2007.00765.x
更新日期:2008-01-01 00:00:00
abstract::The primary aim of this study was to compare the maximal oxygen uptake as evaluated from a submaximal exercise test (EVO2peak) to direct measurements of VO2peak during a maximal exercise test as means of monitoring the aerobic endurance capacity in women with type 2 diabetes (T2D). Twenty-seven women with T2D particip...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2008.00808.x
更新日期:2008-09-01 00:00:00
abstract::Physical therapy treatments for and evaluation of lower limb swelling are usually performed in supine lying position. However, the limb is usually treated or assessed in the dependent position, i.e. sitting or standing. The purpose of this study was to determine the possible confounding effect of subject positioning o...
journal_title:Clinical physiology and functional imaging
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1475-097X.2004.00578.x
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:Early identification of haemorrhage is difficult when a bleeding site is not apparent. This study explored the potential use of the finger photoplethysmographic (PPG) waveform derived left ventricular ejection time (LVET(p)) and pulse transit time (PTT) for detecting blood loss, by using blood donation as a ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2008.00843.x
更新日期:2009-05-01 00:00:00
abstract::The purpose of this study was to examine the effectiveness of maximal and rapid isometric torque characteristics of the hip extensor muscles and postural balance performance to discriminate between female collegiate soccer athletes and non-athlete controls. Ten athletes (mean ± SE: age = 19·20 ± 0·36 year; mass = 62·2...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12167
更新日期:2015-07-01 00:00:00
abstract::The aim was to investigate and compare the effects of proprioceptive neuromuscular facilitation (PNF) and static stretching (SS) on maximal voluntary contraction (MVC) and muscle activation in indoor soccer players. Thirty-three young adult men were divided into two groups: (i) sedentary and (ii) trained. Each group c...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12047
更新日期:2013-11-01 00:00:00
abstract::Previous studies have indicated that, during mechanical ventilation, an inspiratory pause enhances gas exchange. This has been attributed to prolonged time during which fresh gas of the tidal volume is present in the respiratory zone and is available for distribution in the lung periphery. The mean distribution time o...
journal_title:Clinical physiology and functional imaging
pub_type: 临床试验,杂志文章
doi:10.1111/j.1475-097X.2007.00699.x
更新日期:2007-01-01 00:00:00
abstract::The renin-angiotensin system (RAS) is developmentally up-regulated and it is essential for kidney development in several species. Given the fact that the rat lung undergoes postnatal development, the mammalian lung possesses the highest angiotensin-converting enzyme (ACE) levels and ACE activity increases during the f...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1046/j.1475-0961.2003.00530.x
更新日期:2004-01-01 00:00:00
abstract::This study examined the effect of exercise intensity on the kinetics of muscle oxygen consumption in non-exercising forearm flexor muscles (VO(2mf)) during exercise. Seven healthy male subjects performed cycling exercise for 60 min at 30% of maximal oxygen consumption (%VO(2max)) and 30 min at 50% VO(2max) on separate...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1475-097X.2011.01073.x
更新日期:2012-05-01 00:00:00
abstract:OBJECTIVE:Due to delivery problems with the most commonly used bone scintigraphic agent medronate-(99m)Tc-methylene diphosphonate (MDP) (medronate), several regional institutions changed, at various time points, to (99m)Tc-dicarboxypropane diphosphonate (DPD) (Teceos) from 2010. Extraosseous uptake, in particular, myoc...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12219
更新日期:2016-05-01 00:00:00
abstract::Short axis (SA) images obtained from cardiac magnetic resonance imaging are used to advantage in the calculation of important clinical parameters such as the ejection fraction and stroke volume (SV). A prerequisite for these calculations is the separation of the left ventricle and the left atrium. When only using the ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2008.00799.x
更新日期:2008-07-01 00:00:00
abstract::The stroke volume (SV) during exercise is an important index of the heart's functional capacity. A new method has been developed for the non-invasive estimation of exercise SV (SVex). It requires the determination of the slope for the oxygen uptake versus heart rate relationship in the steady state of graded exercise ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2004.00585.x
更新日期:2005-01-01 00:00:00
abstract::Given the important role of the shoulder sensorimotor system in shoulder stability, its assessment appears of interest. Force platform monitoring of centre of pressure (CoP) in upper-limb weight-bearing positions is of interest as it allows integration of all aspects of shoulder sensorimotor control. This study aimed ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2012.01140.x
更新日期:2012-09-01 00:00:00
abstract::Patients with nemaline myopathy, a muscle disorder primarily affecting the thin filaments, suffer from weakness which is poorly understood. As disturbed excitation-contraction coupling has been suggested as a possible mechanism, the present study was designed to investigate whether the contractile properties of the kn...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2007.00740.x
更新日期:2007-07-01 00:00:00
abstract:BACKGROUND:Autonomic dysfunction (AD) and cardiopulmonary exercise testing (CPET) parameters have been associated with masked heart failure with preserved ejection fraction (HFpEF) in the general population. Their clinical significance for masked HFpEF in chronic obstructive pulmonary disease (COPD) is however elusive....
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12623
更新日期:2020-07-01 00:00:00
abstract::Magnetic resonance imaging (MRI) of the abdomen is a widely established imaging modality in the diagnostic workup of patients suffering from abdominal disorders. Small-bowel motility analyses using MRI have recently been introduced to provide functional information about the intestine not provided by morphological ana...
journal_title:Clinical physiology and functional imaging
pub_type: 临床试验,杂志文章
doi:10.1111/cpf.12124
更新日期:2015-01-01 00:00:00
abstract:UNLABELLED:Myocardial perfusion imaging with single-photon emission computed tomography (SPECT) is useful for the evaluation of patients with known or suspected coronary artery disease. Parameters of interest are the reduction in the blood perfusion (severity) and the lesion volume (extent). The aim of this study was t...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2006.00705.x
更新日期:2006-11-01 00:00:00
abstract::The aim was to validate possible vasodilating effects of a Ginkgo biloba extract with a secondary aim of finding a pharmacodynamic signal relating to the active component of these extracts. We studied the effect of G. biloba extract on forearm haemodynamics in 16 healthy subjects (nine females, seven males) with a med...
journal_title:Clinical physiology and functional imaging
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1046/j.1475-097x.2002.00445.x
更新日期:2002-11-01 00:00:00
abstract:PURPOSE:To validate ironload T2* by automatic inline Maximum Likelihood Estimate (MLE) with k-space Rician noise correction, against the manual and automated truncation, as well as offset methods, in phantoms and in heart and liver in patients. METHODS:Twenty-five patients and an iron-oxide phantom were scanned at 1.5...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12303
更新日期:2017-05-01 00:00:00
abstract::Across various populations, verification testing is used to confirm VO(2)max attainment and has repeatedly shown similar VO(2)max values to those obtained from incremental exercise. Yet, many individuals show meaningful differences in VO(2)max between protocols, and an explanation for this is unknown. The aim of the s...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2010.00940.x
更新日期:2010-07-01 00:00:00
abstract::Monitoring alterations in fingertip temperature during ischaemia and the subsequent hyperaemia provides a novel way of studying microvascular reactivity. The relations between parameters characterizing blood perfusion and the thermal response of fingertips were studied using experimental and theoretical approaches. Du...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2010.00981.x
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:The use of radioactive compounds for sentinel node biopsy is now a generally accepted part of the surgical treatment of breast cancer and melanoma, with the risk of radiation exposure to the operating team. The aim of this investigation was to study the levels of this exposure in relation to the permissible ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2005.00611.x
更新日期:2005-07-01 00:00:00
abstract::In this study, we examined possible differences in brain activation between smooth pursuit and optokinetic reflexive (OKR) eye movements using functional magnetic resonance imaging (fMRI). Eighteen healthy subjects performed two different eye movement paradigms. In the first paradigm, smooth pursuit eye movements were...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2009.00858.x
更新日期:2009-07-01 00:00:00
abstract::Sixty percent of stroke volume (SV) is generated by atrioventricular plane displacement (AVPD) in a healthy left ventricle (LV). The aims were to determine the effect of ST-elevation myocardial infarction (STEMI) on AVPD and contribution of AVPD to SV and to study the relationship between AVPD and infarct size (IS) an...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12521
更新日期:2018-04-27 00:00:00
abstract::The relationships between electromyographic (EMG) activity and force as well as muscle blood flow and work have been well established. However, the association between muscle blood flow and EMG activity remains unsolved. Thus, to test the hypothesis that muscle EMG activity relates to muscle perfusion in different com...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2006.00656.x
更新日期:2006-03-01 00:00:00
abstract::Blood flow (BF) in exercising muscles is an important factor for exercise capacity. Recently, a non-invasive method to estimate capillary BF (Qcap ) was introduced. Using this method, the Fick principle is re-arranged by using relative differences in deoxygenated haemoglobin (ΔHHb) as a surrogate for arteriovenous O2 ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12434
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:In children, exercise-induced dyspnea is a common symptom that can be due to dysfunctional breathing. EVH test has bee used especially in elite athletes as bronchoprovocation test. Currently, there are only few studies on the EVH test. New research methods are required alongside the traditionally used tests ...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/cpf.12458
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Duplex ultrasound (DUS) has shown a >90% accuracy compared to angiography, concerning the degree of internal carotid artery (ICA) stenosis. However, uncertainty may occur in a severe stenosis, in which peak systolic velocity (PSV) may decrease owing to high flow resistance or high backward pressure. We inves...
journal_title:Clinical physiology and functional imaging
pub_type: 杂志文章
doi:10.1111/j.1475-097X.2011.01118.x
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Cardiac magnetic resonance imaging (CMR) is a promising method for detecting coronary artery disease (CAD). The first reports of new diagnostic techniques indicated generally unrealistic diagnostic performance relying on retrospectively observed cut-off values of quantitative parameters. Although visual anal...
journal_title:Clinical physiology and functional imaging
pub_type: 临床试验,杂志文章
doi:10.1111/j.1475-097X.2009.00908.x
更新日期:2010-03-01 00:00:00