Abstract：
:Perhaps, oxidative stress progresses pupation in some Lepidopteran insects; however, the reasons for this remain obscure. In our previous study, we clarified Bombyx mori SOD1 (BmSOD1) and B. mori SOD2 (BmSOD2) proteins respond in common to ultraviolet irradiation (UV) oxidative stress and metamorphosis. This result strongly suggested pupation initiates by oxidative stress and might mediate by down-regulation of expression of BmSOD1 and BmSOD2 proteins. Thus, we examined about these relationships in B. mori in this study. In the microarray data reanalysis, we found the Notch signaling pathways as the common pathways in pupation and UV oxidative stress in B. mori. Also, we showed a molting hormone, 20-hydroxyecdysone, leads not only generation of superoxide but also downregulation of the expression of BmSOD proteins during pupation in B. mori. Our findings can contribute to a deeper understanding of how biological defense systems work against environmental oxidative stress.
journal_name
Sci Repjournal_title
Scientific reportsauthors
Nojima Y,Bono H,Yokoyama T,Iwabuchi K,Sato R,Arai K,Tabunoki Hdoi
10.1038/s41598-019-51163-3subject
Has Abstractpub_date
2019-10-11 00:00:00pages
14693issue
1issn
2045-2322pii
10.1038/s41598-019-51163-3journal_volume
9pub_type
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journal_title：Scientific reports
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pub_type： 已发布勘误
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更新日期：2014-07-11 00:00:00
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更新日期：2017-01-06 00:00:00
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pub_type： 杂志文章,meta分析
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更新日期：2016-10-11 00:00:00
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