Abstract：
PURPOSE OF REVIEW:Use of antihypertensives in older adults can be complicated by the potential for undesired effects on comorbidities, adverse effects of the drugs, and overall medication burden. The purpose of this two-part review is to discuss contemporary issues encountered in the management of hypertension in aged individuals, with a particular focus on considerations for the individualization of treatment. In Part 2, we discuss the individualized approach to treating hypertension in the elderly. RECENT FINDINGS:Achieving lower blood pressure goals in older adults has the potential to increase risks for complications such as hypotension and acute renal insufficiency, especially in those less healthy. Because elderly exhibit many different phenotypes, a one-size-fits-all approach to treatment goals and choice of antihypertensives is problematic. Many areas of uncertainty remain, including what the optimal goal blood pressure should be in frail or institutionalized elderly, whether there is an upper age limit for treatment initiation where benefits and risks overlap, and when de-escalation of antihypertensives should be considered. Hypertension is a major modifiable risk factor, and the benefits of treatment in lowering cardiovascular events are realized for most individuals, even at advanced ages. Areas of uncertainty in the management of hypertension in this group mandate a cautious, individualized approach to treatment which relies on careful assessment of biologic or phenotypic age, rather than chronologic age alone.
journal_name
Curr Hypertens Repjournal_title
Current hypertension reportsauthors
Ernst ME,MacLaughlin EJdoi
10.1007/s11906-019-0988-xsubject
Has Abstractpub_date
2019-10-10 00:00:00pages
83issue
11eissn
1522-6417issn
1534-3111pii
10.1007/s11906-019-0988-xjournal_volume
21pub_type
杂志文章,评审abstract：PURPOSE OF REVIEW:To review data supporting the use of home blood pressure monitoring (HBPM) and provide practical guidance to clinicians wishing to incorporate HBPM into their practice. RECENT FINDINGS:HBPM more accurately reflects the risk of cardiovascular events than office blood pressure measurement. In addition,...
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更新日期：2019-02-12 00:00:00
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更新日期：2019-02-12 00:00:00
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更新日期：2019-02-12 00:00:00
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journal_title：Current hypertension reports
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更新日期：2012-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：2018-08-07 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
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更新日期：2015-05-01 00:00:00
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更新日期：2019-08-02 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
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更新日期：2006-06-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
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更新日期：2016-06-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-003-0083-0
更新日期：2003-10-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
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更新日期：2016-07-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-001-0082-y
更新日期：2001-02-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-002-0021-6
更新日期：2002-12-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-018-0810-1
更新日期：2018-02-26 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-003-0005-1
更新日期：2003-02-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
doi：10.1007/s11906-008-0075-1
更新日期：2008-10-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
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更新日期：2008-10-01 00:00:00
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journal_title：Current hypertension reports
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pub_type： 杂志文章,评审
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更新日期：2018-02-26 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2018-03-19 00:00:00
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pub_type： 杂志文章,评审
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
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更新日期：2004-06-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
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更新日期：2011-12-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
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更新日期：2001-04-01 00:00:00
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journal_title：Current hypertension reports
pub_type： 杂志文章,评审
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更新日期：2008-06-01 00:00:00
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更新日期：2005-12-01 00:00:00
