A microcosm approach highlights the response of soil mineral weathering bacterial communities to an increase of K and Mg availability.

abstract：:Argininosuccinate synthetase 1 (ASS1) is the key enzyme that controls biosynthesis of arginine (Arg). ASS1 is silenced in many human malignancies therefore, these tumors require extracellular Arg for growth. The Arg-degrading recombinant protein, pegylated arginine deiminase (ADI-PEG20), has been in clinical trials fo...

journal_title：Scientific reports

authors： Tsai WB,Long Y,Chang JT,Savaraj N,Feun LG,Jung M,Chen HHW,Kuo MT

更新日期：2017-09-07 00:00:00

abstract：:We analyzed the clinicopathological features of 9 breast malignant fibrous histiocytoma (MFH) patients. Immunohistochemistry was used to make both diagnosis and differential diagnosis, and to identify prognostic factors. All tumors lacked epithelial markers but expressed mesenchymal markers, suggesting a mesenchymal o...

journal_title：Scientific reports

authors： Qiu SQ,Wei XL,Huang WH,Wu MY,Qin YS,Li YK,Zhang GJ

更新日期：2013-01-01 00:00:00

abstract：:Because of ubiquity of thioesters, thioesterases play a critical role in metabolism, membrane biosynthesis, signal transduction, and gene regulation. In many bacteria, YbgC is such an enzyme, whose coding gene mostly resides in the tol-pal cluster. Although all other proteins encoded in the tol-pal cluster are clearly...

journal_title：Scientific reports

authors： Gao T,Meng Q,Gao H

更新日期：2017-06-21 00:00:00

abstract：:Modeling the dynamic nature of protein-ligand binding with atomistic simulations is one of the main challenges in computational biophysics, with important implications in the drug design process. Although in the past few years hardware and software advances have significantly revamped the use of molecular simulations,...

journal_title：Scientific reports

authors： Lecina D,Gilabert JF,Guallar V

更新日期：2017-08-16 00:00:00

abstract：:The synthesis of ordered monolayers of gold nano-urchin (Au-NU) nanostructures with controlled size, directly on thin films using a simple electrochemical method is reported in this study. In order to demonstrate one of the vast potential applications, the developed Au-NUs were formed on the electrodes of transducers ...

journal_title：Scientific reports

authors： Sabri YM,Kandjani AE,Ippolito SJ,Bhargava SK

更新日期：2016-04-19 00:00:00

abstract：:Alternative polyadenylation has been recognized as a key contributor of gene expression regulation by generating different transcript isoforms with altered 3' ends. Although polyadenylation is well known for marking the end of a 3' UTR, an increasing number of studies have reported previously less-addressed polyadenyl...

journal_title：Scientific reports

authors： Guo C,Spinelli M,Liu M,Li QQ,Liang C

更新日期：2016-06-15 00:00:00

abstract：:We aimed to assess feasibility of a support vector machine (SVM) texture classifier to discriminate pathologic infiltration patterns from the normal bone marrows in MRI. This retrospective study included 467 cases, which were split into a training (n = 360) and a test set (n = 107). A sagittal T1-weighted lumbar spina...

journal_title：Scientific reports

authors： Hwang EJ,Jung JY,Lee SK,Lee SE,Jee WH

更新日期：2019-04-15 00:00:00

abstract：:Among vector-borne diseases malaria is the leading cause of morbidity in the world, with more than 200 million cases per year and a large number of deaths. The techniques traditionally used for the detection of Plasmodium in humans and Anopheles mosquitoes include microscopy, IRMA, ELISA, antibody or molecular assays,...

journal_title：Scientific reports

authors： Murillo E,Muskus C,Agudelo LA,Vélez ID,Ruiz-Lopez F

更新日期：2019-02-08 00:00:00

abstract：:In this work we derive an effective Hamiltonian for the surface states of a hollow topological insulator (TI) nanotube with finite width walls. Unlike a solid TI cylinder, a TI nanotube possesses both an inner as well as outer surface on which the states localized at each surface are coupled together. The curvature al...

journal_title：Scientific reports

authors： Siu ZB,Tan SG,Jalil MB

更新日期：2017-04-03 00:00:00

abstract：:We investigated the physiological functions of Myo10 (myosin X) using Myo10 reporter knockout (Myo10tm2) mice. Full-length (motorized) Myo10 protein was deleted, but the brain-specific headless (Hdl) isoform (Hdl-Myo10) was still expressed in homozygous mutants. In vitro, we confirmed that Hdl-Myo10 does not induce fi...

journal_title：Scientific reports

authors： Bachg AC,Horsthemke M,Skryabin BV,Klasen T,Nagelmann N,Faber C,Woodham E,Machesky LM,Bachg S,Stange R,Jeong HW,Adams RH,Bähler M,Hanley PJ

更新日期：2019-01-24 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Nik ME,Malaekeh-Nikouei B,Amin M,Hatamipour M,Teymouri M,Sadeghnia HR,Iranshahi M,Jaafari MR

更新日期：2020-02-27 00:00:00

abstract：:Early microvascular damage in diabetes (e.g. capillary nonperfusion and ischemia) can now be assessed and quantified with optical coherence tomography-angiography (OCT-A). The morphology of vascular tissue is indeed affected by different factors; however, there is a paucity of data examining whether OCT-A metrics are ...

journal_title：Scientific reports

authors： Tang FY,Ng DS,Lam A,Luk F,Wong R,Chan C,Mohamed S,Fong A,Lok J,Tso T,Lai F,Brelen M,Wong TY,Tham CC,Cheung CY

更新日期：2017-05-31 00:00:00

abstract：:Nisin inhibits bacterial growth by generating pores in cell membrane and interrupting cell-wall biosynthesis through specific lipid II interaction. However, the role of the hinge region and C-terminus residues of the peptide in antibacterial action of nisin is largely unknown. Here, using molecular dynamics simulation...

journal_title：Scientific reports

authors： Prince A,Sandhu P,Ror P,Dash E,Sharma S,Arakha M,Jha S,Akhter Y,Saleem M

更新日期：2016-11-29 00:00:00

abstract：:The prognostic factors for survival among patients with secondary osteosarcoma remain unclear. The aim of this study was to develop a practical nomogram for predicting cancer-specific survival (CSS) in patients with osteosarcoma as a secondary malignancy. The surveillance, epidemiology, and end results database was us...

journal_title：Scientific reports

authors： He Y,Liu H,Wang S,Zhang J

更新日期：2020-07-30 00:00:00

abstract：:Human papillomavirus (HPV) infection, a primary cause of genital cancer, is also related to the increasing incidence of oropharyngeal cancer among young men. Relatively little is known about the concurrence of oral and genital infection among healthy individuals. Oral and genital swab exfoliated cells were collected s...

journal_title：Scientific reports

authors： Liu F,Hang D,Deng Q,Liu M,Xi L,He Z,Zhang C,Sun M,Liu Y,Li J,Pan Y,Ning T,Guo C,Liang Y,Xu R,Zhang L,Cai H,Ke Y

更新日期：2015-10-27 00:00:00

abstract：:The ability to measure biomolecular dynamics within cells and tissues is very important to understand fundamental physiological processes including cell adhesion, signalling, movement, division or metabolism. Usually, such information is obtained using particle tracking methods or single point fluctuation spectroscopy...

journal_title：Scientific reports

authors： Hedde PN,Stakic M,Gratton E

更新日期：2014-11-14 00:00:00

abstract：:Most pancreatic cancer (PC) patients manifest multiple liver metastases at the time of diagnosis. Activated platelets play a key role in tumor growth and tumor metastases. Mean platelet volume (MPV) is a platelet index and is altered in patients with malignancies. This study aimed to evaluate whether MPV can effective...

journal_title：Scientific reports

authors： Yin JB,Wang X,Zhang X,Liu L,Wang RT

更新日期：2018-04-16 00:00:00

abstract：:Quantum walks often provide telling insights about the structure of the system on which they are performed. In [Formula: see text]-symmetric and lossy dimer lattices, the topological properties of the band structure manifest themselves in the quantization of the mean displacement of such a walker. We investigate the f...

journal_title：Scientific reports

authors： Harter AK,Saxena A,Joglekar YN

更新日期：2018-08-13 00:00:00

abstract：:Endothelin-1 (ET-1) is associated with endothelial dysfunction and vasoconstriction. Increased circulating ET-1 levels are associated with long-term cardiovascular mortality. Renalase, released from kidney, metabolizes catecholamines and regulates blood pressure. An increase in circulating renalase levels has been rep...

journal_title：Scientific reports

authors： Li YH,Sheu WH,Lee WJ,Wang J-,Fu CP,Liang KW,Lee IT

更新日期：2018-05-09 00:00:00

abstract：:Orb2 is a functional amyloid that plays a key role in Drosophila long-term memory formation. Orb2 has two isoforms that differ in their N-termini. The N-terminus of the A isoform (Orb2A) that precedes its Q-rich prion-like domain has been shown to be important for Orb2 aggregation and long-term memory. However, beside...

journal_title：Scientific reports

authors： Cervantes SA,Bajakian TH,Soria MA,Falk AS,Service RJ,Langen R,Siemer AB

更新日期：2016-12-06 00:00:00

abstract：:In this paper, we propose a real time, ultrahigh accuracy and full-field-of-view (RUF) algorithm for full field of view (FOV) imaging system. The proposed algorithm combines rough matching and precise matching method to stitch multiple images with the whole FOV in short time and high imaging quality. In order to verif...

journal_title：Scientific reports

authors： Liu SB,Wang JH,Yuan RY,Zhao WX,Li L,Wang QH

更新日期：2020-07-24 00:00:00

abstract：:Although human induced pluripotent stem cell (hiPSC) lines are karyotypically normal, they retain the potential for mutation in the genome. Accordingly, intensive and relevant quality controls for clinical-grade hiPSCs remain imperative. As a conceptual approach, we performed RNA-seq-based broad-range genetic quality ...

journal_title：Scientific reports

authors： Jo HY,Han HW,Jung I,Ju JH,Park SJ,Moon S,Geum D,Kim H,Park HJ,Kim S,Stacey GN,Koo SK,Park MH,Kim JH

更新日期：2020-03-03 00:00:00

abstract：:Many species can successfully colonize new areas despite their propagules having low genetic variation. We assessed whether the decreased genetic diversity could result in temporal fluctuations of genetic parameters of the new populations of an invasive species, western flower thrips, Frankliniella occidentalis, using...

journal_title：Scientific reports

authors： Yang XM,Lou H,Sun JT,Zhu YM,Xue XF,Hong XY

更新日期：2015-07-03 00:00:00

abstract：:Hydrostatic pressure is an important environmental factor affecting the vertical distribution of marine organisms. Laboratory-based studies have shown that many extant shallow-water marine benthic invertebrates can tolerate hydrostatic pressure outside their known natural distributions. However, only a few studies hav...

journal_title：Scientific reports

authors： Chen J,Liu H,Cai S,Zhang H

更新日期：2019-03-05 00:00:00

abstract：:To identify novel phenotypic associations related to Cytochrome P450 Family 2 Subfamily A Member 6 (CYP2A6), we investigated the human phenome in a total of 11,271 individuals. Initially, we conducted a phenome-wide association study in 3,401 nicotine-exposed elderly subjects considering 358 phenotypic traits. We iden...

journal_title：Scientific reports

authors： Polimanti R,Jensen KP,Gelernter J

更新日期：2017-04-21 00:00:00

abstract：:The study aimed to explore the epidemiology and clinical characteristics of chronic osteomyelitis observed in a northern China hospital. Clinical data of 255 patients with chronic osteomyelitis from January 2007 to January 2014 were collected and analyzed, including general information, disease data, treatment and fol...

journal_title：Scientific reports

authors： Ma X,Han S,Ma J,Chen X,Bai W,Yan W,Wang K

更新日期：2018-10-05 00:00:00

abstract：:Electrochemical biosensors have been studied intensively for several decades. Numerous sensing concepts and related interface architectures have been developed. However, all such architectures suffer a trade-off: simple architectures favour usability, whereas complex architectures favour better performance. To overcom...

journal_title：Scientific reports

authors： Zhu X,Feng C,Ye Z,Chen Y,Li G

更新日期：2014-02-25 00:00:00

abstract：:As variations in the chromosome number are recognized to be of evolutionary interest but are also widely debated in the literature, we aimed to quantitatively test for possible relationships among the chromosome number, plant traits, and environmental factors. In particular, the chromosome number and drivers of its va...

journal_title：Scientific reports

authors： Carta A,Bedini G,Peruzzi L

更新日期：2018-09-24 00:00:00

abstract：:Local translation of membrane proteins in neuronal subcellular domains like soma, dendrites and axon termini is well-documented. In this study, we isolated the electrical signaling unit of an axon by dissecting giant axons from mature squids (Dosidicus gigas). Axoplasm extracted from these axons was found to contain r...

journal_title：Scientific reports

authors： Mathur C,Johnson KR,Tong BA,Miranda P,Srikumar D,Basilio D,Latorre R,Bezanilla F,Holmgren M

更新日期：2018-02-02 00:00:00

abstract：:Settlement-inducing protein complex (SIPC) is a pheromone that triggers conspecific larval settlement in the barnacle Amphibalanus amphitrite. In the present study, immunostaining and scanning electron microscopy of SIPC revealed signals in the frontal horn pores and the secretions from carapace pores, suggesting that...

journal_title：Scientific reports

authors： Zhang G,Yang XX,Leung PM,He LS,Chan TY,Yan GY,Zhang Y,Sun J,Xu Y,Qian PY

更新日期：2016-07-20 00:00:00