Abstract:
:Indisputably, cancer is a global crisis that requires immediate intervention. Despite the use of conventional treatments over the past decades, it is acceptable to admit that these are expensive, invasive, associated with many side effects and, therefore, a reduced quality of life. One of the most possible solutions to this could be the use of gold nanoparticle (AuNP) conjugated photodynamic therapy (PDT) in combination with cannabidiol (CBD), a Cannabis derivative from the Cannabis sativa. Since the use of Cannabis has always been associated with recreation and psychoactive qualities, the positive effects of Cannabis or its derivatives on cancer treatment have been misunderstood and hence misinterpreted. On the other hand, AuNP-PDT is the most favoured form of treatment for cancer, due to its augmented specificity and minimal risk of side effects compared to conventional treatments. However, its use requires the consideration of several physical, biologic, pharmacologic and immunological factors, which may hinder its effectiveness if not taken into consideration. In this review, the role of gold nanoparticle mediated PDT combined with CBD treatment on breast cancer cells will be deliberated.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
R Mokoena D,P George B,Abrahamse Hdoi
10.3390/ijms20194771subject
Has Abstractpub_date
2019-09-26 00:00:00issue
19issn
1422-0067pii
ijms20194771journal_volume
20pub_type
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journal_title:International journal of molecular sciences
pub_type: 历史文章,杂志文章
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journal_title:International journal of molecular sciences
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