Alcohol use disorder and risk of sensitization to environmental allergens in Sub-Continental Asian Indian males.

Abstract:

:Alcohol is known to cause elevation of serum total IgE (tIgE). Whether it can predispose to allergic disorders, however, is not clear. To assess whether alcohol can cause sensitization to allergens, we analyzed 100 individuals with alcohol use disorder (AUD) and 50 matched healthy controls. Serum tIgE and specific IgE against environmental allergens were measured. We found 93% of individuals with AUD had raised tIgE compared to only 48% of healthy controls (p < 0.0001). Sensitization to aeroallergens was noted in 68% drinkers compared to 24% of controls (p < 0.0001). The degree of sensitization was directly proportional to the amount and duration of alcohol intake. There is a possibility of a link between alcohol abuse and allergic sensitization.

journal_name

J Addict Dis

authors

Kumar Y,Laxmi P,Minz RW,Pal A

doi

10.1080/10550887.2019.1665964

subject

Has Abstract

pub_date

2018-07-01 00:00:00

pages

227-232

issue

3-4

eissn

1055-0887

issn

1545-0848

journal_volume

37

pub_type

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