Abstract:
:Alcohol is known to cause elevation of serum total IgE (tIgE). Whether it can predispose to allergic disorders, however, is not clear. To assess whether alcohol can cause sensitization to allergens, we analyzed 100 individuals with alcohol use disorder (AUD) and 50 matched healthy controls. Serum tIgE and specific IgE against environmental allergens were measured. We found 93% of individuals with AUD had raised tIgE compared to only 48% of healthy controls (p < 0.0001). Sensitization to aeroallergens was noted in 68% drinkers compared to 24% of controls (p < 0.0001). The degree of sensitization was directly proportional to the amount and duration of alcohol intake. There is a possibility of a link between alcohol abuse and allergic sensitization.
journal_name
J Addict Disjournal_title
Journal of addictive diseasesauthors
Kumar Y,Laxmi P,Minz RW,Pal Adoi
10.1080/10550887.2019.1665964subject
Has Abstractpub_date
2018-07-01 00:00:00pages
227-232issue
3-4eissn
1055-0887issn
1545-0848journal_volume
37pub_type
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journal_title:Journal of addictive diseases
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journal_title:Journal of addictive diseases
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journal_title:Journal of addictive diseases
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journal_title:Journal of addictive diseases
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doi:10.1080/10550887.2016.1139428
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journal_title:Journal of addictive diseases
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doi:10.1080/10550887.2016.1186413
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journal_title:Journal of addictive diseases
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doi:10.1300/j069v11n02_02
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pub_type: 临床试验,杂志文章,随机对照试验
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