Canonical Wnt Signaling Sets the Pace.

Abstract:

:In this issue of Developmental Cell, Ren et al. (2019) identify the embryonic origin of cardiac pacemaker cells in zebrafish and implicate Wnt5b in promoting their differentiation. Furthermore, canonical Wnt activation in human stem cell-derived cardiac progenitors produces functional pacemaker cells in vitro, advancing the therapeutic potential of biological pacemakers.

journal_name

Dev Cell

journal_title

Developmental cell

authors

Burns CG,Burns CE

doi

10.1016/j.devcel.2019.09.002

subject

Has Abstract

pub_date

2019-09-23 00:00:00

pages

675-676

issue

6

eissn

1534-5807

issn

1878-1551

pii

S1534-5807(19)30731-2

journal_volume

50

pub_type

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