Phenotypic characterisation of regulatory T cells in dogs reveals signature transcripts conserved in humans and mice.

abstract：:The freshwater crustacean Daphnia is known for its ability to develop inducible morphological defences that thwart predators. These defences are developed only in the presence of predators and are realized as morphological shape alterations e.g. 'neckteeth' in D. pulex and 'crests' in D. longicephala. Both are discuss...

journal_title：Scientific reports

authors： Kruppert S,Horstmann M,Weiss LC,Witzel U,Schaber CF,Gorb SN,Tollrian R

更新日期：2017-08-29 00:00:00

abstract：:Relative gene expression analyses by RT-qPCR (reverse transcription-quantitative PCR) are highly dependent on the reference genes in normalizing the expression data of target genes. Therefore, inappropriate endogenous control genes will lead to inaccurate target gene expression profiles, and the selection and validati...

journal_title：Scientific reports

authors： Liang L,He Z,Yu H,Wang E,Zhang X,Zhang B,Zhang C,Liang Z

更新日期：2020-01-28 00:00:00

abstract：:Flagellin is amongst the most abundant proteins in flagellated bacterial species and constitutes the major building block of the flagellar filament. The proteins FliW and FliS serve in the post-transcriptional control of flagellin and guide the protein to the flagellar type III secretion system (fT3SS), respectively. ...

journal_title：Scientific reports

authors： Altegoer F,Mukherjee S,Steinchen W,Bedrunka P,Linne U,Kearns DB,Bange G

更新日期：2018-08-01 00:00:00

abstract：:Metasurfaces are ideal candidates for conformal wave manipulation on curved objects due to their low profiles and rich functionalities. Here we design and analyze conformal metasurfaces for practical optical applications at 532 nm visible band for the first time. The inclusions are silicon disk nanoantennas embedded i...

journal_title：Scientific reports

authors： Cheng J,Jafar-Zanjani S,Mosallaei H

更新日期：2016-12-08 00:00:00

abstract：:The general disease burden associated with the restrictive spirometric pattern (RSP) is substantial. However, the impact of RSP by its severity on general health problems and quality of life has not been well elucidated. This study aimed to analyse nutrition, physical activity, and quality of life in subjects who part...

journal_title：Scientific reports

authors： Chung SJ,Kim HI,Yang B,Kim T,Sim YS,Kang HK,Kim SH,Yoon HJ,Choi H,Lee H

更新日期：2020-11-12 00:00:00

abstract：:Envelope (E) and temporal fine structure (TFS) are important features of acoustic signals and their corresponding perceptual function has been investigated with various listening tasks. To further understand the underlying neural processing of TFS, experiments in humans and animals were conducted to demonstrate the ef...

journal_title：Scientific reports

authors： Xu Y,Chen M,LaFaire P,Tan X,Richter CP

更新日期：2017-10-17 00:00:00

abstract：:Viral capsids are metastable structures that perform many essential processes; they also act as robust cages during the extracellular phase. Viruses can use multifunctional proteins to optimize resources (e.g., VP3 in avian infectious bursal disease virus, IBDV). The IBDV genome is organized as ribonucleoproteins (RNP...

journal_title：Scientific reports

authors： Mertens J,Casado S,Mata CP,Hernando-Pérez M,de Pablo PJ,Carrascosa JL,Castón JR

更新日期：2015-09-04 00:00:00

abstract：:The present study investigated when emotion modulates working memory from the perspective of neural activation. Using fMRI, we measured brain activity during the encoding and retrieval phases of a reading span test (RST) that used emotional contexts. The emotional RST required participants to read sentences that elici...

journal_title：Scientific reports

authors： Osaka M,Yaoi K,Minamoto T,Osaka N

更新日期：2013-01-01 00:00:00

abstract：:The Internet of Things is driving extensive efforts to develop intelligent everyday objects. This requires seamless integration of relatively simple electronics, for example through 'stick-on' electronics labels. We believe the future evolution of this technology will be governed by Wright's Law, which was first propo...

journal_title：Scientific reports

authors： Myny K,Smout S,Rockelé M,Bhoolokam A,Ke TH,Steudel S,Cobb B,Gulati A,Gonzalez Rodriguez F,Obata K,Marinkovic M,Pham DV,Hoppe A,Gelinck GH,Genoe J,Dehaene W,Heremans P

更新日期：2014-12-10 00:00:00

abstract：:The abnormal wing discs (awd) gene encodes the Drosophila homolog of NME1/NME2 metastasis suppressor genes. Awd acts in multiple tissues where its function is critical in establishing and maintaining epithelial integrity. Here, we analysed awd gene function in Drosophila epithelial cells using transgene-mediated RNA i...

journal_title：Scientific reports

authors： Romani P,Duchi S,Gargiulo G,Cavaliere V

更新日期：2017-12-04 00:00:00

abstract：:We study propagation in a cyclic symmetric multicore fiber where the core radii randomly fluctuate along the propagation direction. We propose a hybrid analytic-numerical method to optimize the amplitude and frequency of the fluctuations that suppress power transfer between outer and inner cores. This framework allows...

journal_title：Scientific reports

authors： Jaramillo Ávila B,Torres JM,León-Montiel RJ,Rodríguez-Lara BM

更新日期：2019-10-31 00:00:00

abstract：:Monitoring of disease/therapeutic conditions is an important application of circulating tumor DNA (ctDNA). We devised numerical indices, based on ctDNA dynamics, for therapeutic response and disease progression. 52 lung cancer patients subjected to the EGFR-TKI treatment were prospectively collected, and ctDNA levels ...

journal_title：Scientific reports

authors： Kato K,Uchida J,Kukita Y,Kumagai T,Nishino K,Inoue T,Kimura M,Oba S,Imamura F

更新日期：2016-07-06 00:00:00

abstract：:Settlement-inducing protein complex (SIPC) is a pheromone that triggers conspecific larval settlement in the barnacle Amphibalanus amphitrite. In the present study, immunostaining and scanning electron microscopy of SIPC revealed signals in the frontal horn pores and the secretions from carapace pores, suggesting that...

journal_title：Scientific reports

authors： Zhang G,Yang XX,Leung PM,He LS,Chan TY,Yan GY,Zhang Y,Sun J,Xu Y,Qian PY

更新日期：2016-07-20 00:00:00

abstract：:The therapeutic effects of C16, which is an inhibitor of RNA-dependent protein kinase (PKR), on growth of hepatocellular carcinoma (HCC) cells and tumor progression in vitro and in vivo were evaluated. Huh7 cells, a human HCC cell line, were used. The effects of C16 on cell viability were evaluated with the MTT assay,...

journal_title：Scientific reports

authors： Watanabe T,Ninomiya H,Saitou T,Takanezawa S,Yamamoto S,Imai Y,Yoshida O,Kawakami R,Hirooka M,Abe M,Imamura T,Hiasa Y

更新日期：2020-03-20 00:00:00

abstract：:Black phosphorus (BP) materials have attracted considerable attention owing to their ultra-sensitive humidity sensing characteristics because of the natural absorption of water (H2O) molecules on the BP surface caused by the specific 2D layer-crystalline structure. On the other hand, the BP-based humidity sensor is le...

journal_title：Scientific reports

authors： Phan DT,Park I,Park AR,Park CM,Jeon KJ

更新日期：2017-09-05 00:00:00

abstract：:CD4(+)CD25(+) T cells are critical for maintenance of immunologic self-tolerance. We measured the number of CD4(+)CD25(+) cells in the patients with primary malignant hypertension related kidney injury, to explore the molecular pathogenesis of this disease. We selected 30 patients with primary malignant hypertension r...

journal_title：Scientific reports

authors： Huang H,Luo Y,Liang Y,Long X,Peng Y,Liu Z,Wen X,Jia M,Tian R,Bai C,Li C,He F,Lin Q,Wang X,Dong X

更新日期：2016-06-09 00:00:00

abstract：:The motion of a laser-heated Janus particle is experimentally measured under a rotating electric field. Directionally circular motions of the Janus particle following or countering the direction of the rotating electric field are observed in the low-frequency region (from 1 to 6 kHz) depending on the direction of elec...

journal_title：Scientific reports

authors： Chen YL,Yang CX,Jiang HR

更新日期：2018-04-13 00:00:00

abstract：:Soil moisture is an important variable for land-climate and hydrological interactions. To investigate emergent large-scale, long-term interactions between soil moisture and other key hydro-climatic variables (precipitation, actual evapotranspiration, runoff, temperature), we analyze monthly values and anomalies of the...

journal_title：Scientific reports

authors： Ghajarnia N,Kalantari Z,Orth R,Destouni G

更新日期：2020-03-16 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Liu Y,Li J,Yang J,Zeng H,Guo L,Ren S,Sun W,Chen Z,Cong X,Shi J,Chen L,Du Y,Li J,Wang J,Wu J,Yu J

更新日期：2018-05-23 00:00:00

abstract：:To explore the predictive performance of machine learning on the recurrence of patients with gastric cancer after the operation. The available data is divided into two parts. In particular, the first part is used as a training set (such as 80% of the original data), and the second part is used as a test set (the remai...

journal_title：Scientific reports

authors： Zhou C,Hu J,Wang Y,Ji MH,Tong J,Yang JJ,Xia H

更新日期：2021-01-15 00:00:00

abstract：:Marine macroalgal forests are highly productive and iconic ecosystems, which are seriously threatened by number of factors such as habitat destruction, overgrazing, ocean warming, and pollution. The effect of chronic, but low levels of pollutants on the long-term survival of the canopy-forming algae is not well unders...

journal_title：Scientific reports

authors： de Caralt S,Verdura J,Vergés A,Ballesteros E,Cebrian E

更新日期：2020-10-20 00:00:00

abstract：:Online financial markets can be represented as complex systems where trading dynamics can be captured and characterized at different resolutions and time scales. In this work, we develop a methodology based on non-negative tensor factorization (NTF) aimed at extracting and revealing the multi-timescale trading dynamic...

journal_title：Scientific reports

authors： Kobayashi T,Sapienza A,Ferrara E

更新日期：2018-07-25 00:00:00

abstract：:As the natural boundary between the Yunnan-Guizhou Plateau and the Hengduan Mountains in China, the large-scale prominent terrain of Ailaoshan Mountain leads to obvious regional differences in climate and vegetation. In this article, a comparative analysis is made on both species composition and floristic components o...

journal_title：Scientific reports

authors： He SN,Hao CY,Zhao W

更新日期：2019-08-19 00:00:00

abstract：:The activation of the majority of AGC kinases is regulated by two phosphorylation events on two conserved serine/threonine residues located on the activation loop and on the hydrophobic motif, respectively. In AGC kinase family, phosphomimetic substitutions with aspartate or glutamate, leading to constitutive activati...

journal_title：Scientific reports

authors： Somale D,Di Nardo G,di Blasio L,Puliafito A,Vara-Messler M,Chiaverina G,Palmiero M,Monica V,Gilardi G,Primo L,Gagliardi PA

更新日期：2020-01-17 00:00:00

abstract：:Media reports of a celebrity's suicide may be followed by copycat suicides, and the impact may vary in different age and sex subgroups. We proposed a quantitative framework to assess the vulnerability of age and sex subgroups to copycat suicide and used this method to investigate copycat suicides in relation to the su...

journal_title：Scientific reports

authors： Yi H,Hwang J,Bae HJ,Kim N

更新日期：2019-11-21 00:00:00

abstract：:To investigate the evolution of lung function in preterm infants with and without bronchopulmonary dysplasia (BPD) and to determine the perinatal characteristics associated with indexes of lung function in later infancy. Longitudinal lung function assessments were performed at approximately 6, 12, 18, and 24 months of...

journal_title：Scientific reports

authors： Lai SH,Chiang MC,Chu SM,Hsu JF,Yao TC,Tsai MH,Hua MC,Chiu CY,Yeh KW,Huang JL,Liao SL

更新日期：2020-01-16 00:00:00

abstract：:The high growth rate of Ulva seaweeds makes it a potential algal biomass resource. In particular, Ulva meridionalis grows up to fourfold a day. Here, we demonstrated strong carbon fixation by U. meridionalis using 13C stable isotope labelling and traced the 13C flux through sugar metabolites with isotope-ratio mass sp...

journal_title：Scientific reports

authors： Tsubaki S,Nishimura H,Imai T,Onda A,Hiraoka M

更新日期：2020-11-23 00:00:00

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Scientific reports

authors： Li H,Wu S,Ma X,Chen W,Zhang J,Duan S,Gao Y,Kui L,Huang W,Wu P,Shi R,Li Y,Wang Y,Li J,Guo X,Luo X,Li Q,Xiong C,Liu H,Gui M,Sheng J,Dong Y

更新日期：2020-05-18 00:00:00

abstract：:Thermal rectifiers whose forward heat fluxes are greater than reverse counterparts have been extensively studied. Here we have discovered, idealized, and derived the ultimate limit of such rectification ratios, which are partially validated by numerical simulations, experiments, and micro-scale Hamiltonian-oscillator ...

journal_title：Scientific reports

authors： Shih TM,Gao Z,Guo Z,Merlitz H,Pagni PJ,Chen Z

更新日期：2015-08-04 00:00:00

abstract：:The spreading of cooperation in structured population is a challenging problem which can be observed at different scales of social and biological organization. Generally, the problem is studied by evaluating the chances that few initial invading cooperators, randomly appearing in a network, can lead to the spreading o...

journal_title：Scientific reports

authors： Yang G,Cavaliere M,Zhu C,Perc M

更新日期：2021-01-13 00:00:00