Dynamic changes of muscle insulin sensitivity after metabolic surgery.

abstract：:An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...

journal_title：Nature communications

authors： Chen S,Wang Q,Yu H,Capitano ML,Vemula S,Nabinger SC,Gao R,Yao C,Kobayashi M,Geng Z,Fahey A,Henley D,Liu SZ,Barajas S,Cai W,Wolf ER,Ramdas B,Cai Z,Gao H,Luo N,Sun Y,Wong TN,Link DC,Liu Y,Boswell HS,Mayo L

更新日期：2020-07-28 00:00:00

abstract：:Exciton dynamics can be strongly affected by lattice vibrations through electron-phonon coupling. This is rarely explored in two-dimensional magnetic semiconductors. Focusing on bilayer CrI3, we first show the presence of strong electron-phonon coupling through temperature-dependent photoluminescence and absorption sp...

journal_title：Nature communications

authors： Jin W,Kim HH,Ye Z,Ye G,Rojas L,Luo X,Yang B,Yin F,Horng JSA,Tian S,Fu Y,Xu G,Deng H,Lei H,Tsen AW,Sun K,He R,Zhao L

更新日期：2020-09-22 00:00:00

abstract：:Changes in cellular metabolism are associated with the activation of diverse immune subsets. These changes are fuelled by nutrients including glucose, amino acids and fatty acids, and are closely linked to immune cell fate and function. An emerging concept is that nutrients are not equally available to all immune cell...

journal_title：Nature communications

authors： Kedia-Mehta N,Finlay DK

更新日期：2019-05-09 00:00:00

abstract：:Nucleoplasmin (Npm) is a highly conserved histone chaperone responsible for the maternal storage and zygotic release of histones H2A/H2B. Npm contains a pentameric N-terminal core domain and an intrinsically disordered C-terminal tail domain. Though intrinsically disordered regions are common among histone chaperones,...

journal_title：Nature communications

authors： Warren C,Matsui T,Karp JM,Onikubo T,Cahill S,Brenowitz M,Cowburn D,Girvin M,Shechter D

更新日期：2017-12-20 00:00:00

abstract：:Multiphoton absorption processes enable many technologically important applications, such as in vivo imaging, photodynamic therapy and optical limiting, and so on. Specifically, higher-order nonlinear absorption such as five-photon absorption offers significant advantages of greater spatial confinement, increased pene...

journal_title：Nature communications

authors： Chen W,Bhaumik S,Veldhuis SA,Xing G,Xu Q,Grätzel M,Mhaisalkar S,Mathews N,Sum TC

更新日期：2017-05-12 00:00:00

abstract：:Plants can produce organs throughout their entire life from pluripotent stem cells located at their growing tip, the shoot apical meristem (SAM). At the time of flowering, the SAM of Arabidopsis thaliana switches fate and starts producing flowers instead of leaves. Correct timing of flowering in part determines reprod...

journal_title：Nature communications

authors： You Y,Sawikowska A,Neumann M,Posé D,Capovilla G,Langenecker T,Neher RA,Krajewski P,Schmid M

更新日期：2017-05-17 00:00:00

abstract：:The Johnson-Kendall-Roberts theory is the basis of modern contact mechanics. It describes how two deformable objects adhere together, driven by adhesion energy and opposed by elasticity. Here we characterize the indentation of glass particles into soft, silicone substrates using confocal microscopy. We show that, wher...

journal_title：Nature communications

authors： Style RW,Hyland C,Boltyanskiy R,Wettlaufer JS,Dufresne ER

更新日期：2013-01-01 00:00:00

abstract：:Carbon-based three-dimensional aerographite networks, built from interconnected hollow tubular tetrapods of multilayer graphene, are ultra-lightweight materials recently discovered and ideal for advanced multifunctional applications. In order to predict the bulk mechanical behaviour of networks it is very important to...

journal_title：Nature communications

authors： Meija R,Signetti S,Schuchardt A,Meurisch K,Smazna D,Mecklenburg M,Schulte K,Erts D,Lupan O,Fiedler B,Mishra YK,Adelung R,Pugno NM

更新日期：2017-04-12 00:00:00

abstract：:Reduced-dimensional perovskites are attractive light-emitting materials due to their efficient luminescence, color purity, tunable bandgap, and structural diversity. A major limitation in perovskite light-emitting diodes is their limited operational stability. Here we demonstrate that rapid photodegradation arises fro...

journal_title：Nature communications

authors： Na Quan L,Ma D,Zhao Y,Voznyy O,Yuan H,Bladt E,Pan J,García de Arquer FP,Sabatini R,Piontkowski Z,Emwas AH,Todorović P,Quintero-Bermudez R,Walters G,Fan JZ,Liu M,Tan H,Saidaminov MI,Gao L,Li Y,Anjum DH,Wei N,Ta

更新日期：2020-01-10 00:00:00

abstract：:Enhancers are critical for developmental stage-specific gene expression, but their dynamic regulation in plants remains poorly understood. Here we compare genome-wide localization of H3K27ac, chromatin accessibility and transcriptomic changes during flower development in Arabidopsis. H3K27ac prevalently marks promoter...

journal_title：Nature communications

authors： Yan W,Chen D,Schumacher J,Durantini D,Engelhorn J,Chen M,Carles CC,Kaufmann K

更新日期：2019-04-12 00:00:00

abstract：:As a key variance partitioning tool, linear mixed models (LMMs) using genome-based restricted maximum likelihood (GREML) allow both fixed and random effects. Classic LMMs assume independence between random effects, which can be violated, causing bias. Here we introduce a generalized GREML, named CORE GREML, that expli...

journal_title：Nature communications

authors： Zhou X,Im HK,Lee SH

更新日期：2020-08-21 00:00:00

abstract：:LNK (SH2B3) is a key negative regulator of JAK-STAT signaling which has been extensively studied in malignant hematopoietic diseases. We found that LNK is significantly elevated in cutaneous melanoma; this elevation is correlated with hyperactive signaling of the RAS-RAF-MEK pathway. Elevated LNK enhances cell growth ...

journal_title：Nature communications

authors： Ding LW,Sun QY,Edwards JJ,Fernández LT,Ran XB,Zhou SQ,Scolyer RA,Wilmott JS,Thompson JF,Doan N,Said JW,Venkatachalam N,Xiao JF,Loh XY,Pein M,Xu L,Mullins DW,Yang H,Lin DC,Koeffler HP

更新日期：2019-05-20 00:00:00

abstract：:Light-phase-sensitive techniques, such as coherent multidimensional spectroscopy, are well-established in a broad spectral range, already spanning from radio-frequencies in nuclear magnetic resonance spectroscopy to visible and ultraviolet wavelengths in nonlinear optics with table-top lasers. In these cases, the abil...

journal_title：Nature communications

authors： Usenko S,Przystawik A,Jakob MA,Lazzarino LL,Brenner G,Toleikis S,Haunhorst C,Kip D,Laarmann T

更新日期：2017-05-30 00:00:00

abstract：:Adoptive immunotherapy using chimeric antigen receptor (CAR) expressing T cells targeting the CD19 B lineage receptor has demonstrated marked success in relapsed pre-B-cell acute lymphoblastic leukaemia (ALL). Persisting CAR-T cells generate sustained pressure against CD19 that may drive unique mechanisms of resistanc...

journal_title：Nature communications

authors： Jacoby E,Nguyen SM,Fountaine TJ,Welp K,Gryder B,Qin H,Yang Y,Chien CD,Seif AE,Lei H,Song YK,Khan J,Lee DW,Mackall CL,Gardner RA,Jensen MC,Shern JF,Fry TJ

更新日期：2016-07-27 00:00:00

abstract：:Electrospun nanofibres are promising in biomedical applications to replicate features of the natural extracellular matrix (ECM). However, nearly all electrospun scaffolds are either non-degradable or degrade hydrolytically, whereas natural ECM degrades proteolytically, often through matrix metalloproteinases. Here we ...

journal_title：Nature communications

authors： Wade RJ,Bassin EJ,Rodell CB,Burdick JA

更新日期：2015-03-23 00:00:00

abstract：:Following microbial pathogen invasion, one of the main challenges for the host is to rapidly control pathogen spreading to avoid vital tissue damage. Here we report that an effector CD8(+) T-cell population that expresses the marker NK1.1 undergoes delayed contraction and sustains early anti-microbial protection. NK1....

journal_title：Nature communications

authors： Ruiz AL,Soudja SM,Deceneux C,Lauvau G,Marie JC

更新日期：2014-10-06 00:00:00

abstract：:The superconducting state is formed by the condensation of Cooper pairs and protected by the superconducting gap. The pairing interaction between the two electrons of a Cooper pair determines the gap function. Thus, it is pivotal to detect the gap structure for understanding the mechanism of superconductivity. In cupr...

journal_title：Nature communications

authors： Gu Q,Wan S,Tang Q,Du Z,Yang H,Wang QH,Zhong R,Wen J,Gu GD,Wen HH

更新日期：2019-04-08 00:00:00

abstract：:Woody (lignocellulosic) plant biomass is an abundant renewable feedstock, rich in polysaccharides that are bound into an insoluble fiber composite with lignin. Marine crustacean woodborers of the genus Limnoria are among the few animals that can survive on a diet of this recalcitrant material without relying on gut re...

journal_title：Nature communications

authors： Besser K,Malyon GP,Eborall WS,Paro da Cunha G,Filgueiras JG,Dowle A,Cruz Garcia L,Page SJ,Dupree R,Kern M,Gomez LD,Li Y,Elias L,Sabbadin F,Mohamad SE,Pesante G,Steele-King C,Ribeiro de Azevedo E,Polikarpov I,Dupree

更新日期：2018-12-03 00:00:00

abstract：:Sliding clamps encircle DNA and tether polymerases and other factors to the genomic template. However, the molecular mechanism of clamp sliding on DNA is unknown. Using crystallography, NMR and molecular dynamics simulations, here we show that the human clamp PCNA recognizes DNA through a double patch of basic residue...

journal_title：Nature communications

authors： De March M,Merino N,Barrera-Vilarmau S,Crehuet R,Onesti S,Blanco FJ,De Biasio A

更新日期：2017-01-10 00:00:00

abstract：:Storage of anthropogenic CO2 in geological formations relies on a caprock as the primary seal preventing buoyant super-critical CO2 escaping. Although natural CO2 reservoirs demonstrate that CO2 may be stored safely for millions of years, uncertainty remains in predicting how caprocks will react with CO2-bearing brine...

journal_title：Nature communications

authors： Kampman N,Busch A,Bertier P,Snippe J,Hangx S,Pipich V,Di Z,Rother G,Harrington JF,Evans JP,Maskell A,Chapman HJ,Bickle MJ

更新日期：2016-07-28 00:00:00

abstract：:Germline removal provokes longevity in several species and shifts resources towards survival and repair. Several Caenorhabditis elegans transcription factors regulate longevity arising from germline removal; yet, how they work together is unknown. Here we identify a Myc-like HLH transcription factor network comprised ...

journal_title：Nature communications

authors： Nakamura S,Karalay Ö,Jäger PS,Horikawa M,Klein C,Nakamura K,Latza C,Templer SE,Dieterich C,Antebi A

更新日期：2016-03-22 00:00:00

abstract：:During epithelial morphogenesis, cell contacts (junctions) are constantly remodeled by mechanical forces that work against adhesive forces. E-cadherin complexes play a pivotal role in this process by providing persistent cell adhesion and by transmitting mechanical tension. In this context, it is unclear how mechanica...

journal_title：Nature communications

authors： Kale GR,Yang X,Philippe JM,Mani M,Lenne PF,Lecuit T

更新日期：2018-11-27 00:00:00

abstract：:Forebrain neurons have weak intrinsic antioxidant defences compared with astrocytes, but the molecular basis and purpose of this is poorly understood. We show that early in mouse cortical neuronal development in vitro and in vivo, expression of the master-regulator of antioxidant genes, transcription factor NF-E2-rela...

journal_title：Nature communications

authors： Bell KF,Al-Mubarak B,Martel MA,McKay S,Wheelan N,Hasel P,Márkus NM,Baxter P,Deighton RF,Serio A,Bilican B,Chowdhry S,Meakin PJ,Ashford ML,Wyllie DJ,Scannevin RH,Chandran S,Hayes JD,Hardingham GE

更新日期：2015-05-13 00:00:00

abstract：:By electrochemically coupling microbial and abiotic catalysts, bioelectrochemical systems such as microbial electrolysis cells and microbial electrosynthesis systems synthesize energy-rich chemicals from energy-poor precursors with unmatched efficiency. However, to circumvent chemical incompatibilities between the mic...

journal_title：Nature communications

authors： Cornejo JA,Sheng H,Edri E,M Ajo-Franklin C,Frei H

更新日期：2018-06-11 00:00:00

abstract：:6-Phosphogluconate dehydrogenase (6PGD) is a key enzyme that converts 6-phosphogluconate into ribulose-5-phosphate with NADP+ as cofactor in the pentose phosphate pathway (PPP). 6PGD is commonly upregulated and plays important roles in many human cancers, while the mechanism underlying such roles of 6PGD remains elusi...

journal_title：Nature communications

authors： Liu R,Li W,Tao B,Wang X,Yang Z,Zhang Y,Wang C,Liu R,Gao H,Liang J,Yang W

更新日期：2019-03-01 00:00:00

abstract：:The three-dimensional structure of chromosomes plays an important role in gene expression regulation and also influences the repair of radiation-induced DNA damage. Genomic aberrations that disrupt chromosome spatial domains can lead to diseases including cancer, but how the 3D genome structure responds to DNA damage ...

journal_title：Nature communications

authors： Sanders JT,Freeman TF,Xu Y,Golloshi R,Stallard MA,Hill AM,San Martin R,Balajee AS,McCord RP

更新日期：2020-12-02 00:00:00

abstract：:The development of transistors with high gain is essential for applications ranging from switching elements and drivers to transducers for chemical and biological sensing. Organic transistors have become well-established based on their distinct advantages, including ease of fabrication, synthetic freedom for chemical ...

journal_title：Nature communications

authors： Khodagholy D,Rivnay J,Sessolo M,Gurfinkel M,Leleux P,Jimison LH,Stavrinidou E,Herve T,Sanaur S,Owens RM,Malliaras GG

更新日期：2013-01-01 00:00:00

abstract：:Quasicrystals, materials with aperiodic long-range order, have been found in intermetallics, soft materials such as colloids and supermolecules, and also in two-dimensional monolayer films. Here we present the first example of three-dimensional growth of a single-element quasicrystalline film. Using a hitherto unexplo...

journal_title：Nature communications

authors： Sharma HR,Nozawa K,Smerdon JA,Nugent PJ,McLeod I,Dhanak VR,Shimoda M,Ishii Y,Tsai AP,McGrath R

更新日期：2013-01-01 00:00:00

abstract：:For the state-of-the-art quantum dot light-emitting diodes, while the ZnO nanoparticle layers can provide effective electron injections into quantum dots layers, the hole transporting materials usually cannot guarantee sufficient hole injection owing to the deep valence band of quantum dots. Developing proper hole tra...

journal_title：Nature communications

authors： Cao W,Xiang C,Yang Y,Chen Q,Chen L,Yan X,Qian L

更新日期：2018-07-04 00:00:00

abstract：:Mast cells are critical effectors of allergic inflammation and protection against parasitic infections. We previously demonstrated that transcription factors GATA2 and MITF are the mast cell lineage-determining factors. However, it is unclear whether these lineage-determining factors regulate chromatin accessibility a...

journal_title：Nature communications

authors： Li Y,Gao J,Kamran M,Harmacek L,Danhorn T,Leach SM,O'Connor BP,Hagman JR,Huang H

更新日期：2021-01-21 00:00:00