Abstract:
:Highlights A large retrospective study indicates no association between GDM and most types of cancer; this is in contrast to a few smaller studies that have suggested an association with cancer. An increased risk of thyroid cancer in mothers with GDM was demonstrated. While this risk requires further investigation, it may be advisable for physicians to consider regular thyroid examination for patients with a GDM history.
journal_name
J Diabetesjournal_title
Journal of diabetesauthors
Pace R,Rahme E,Dasgupta Kdoi
10.1111/1753-0407.12988subject
Has Abstractpub_date
2020-01-01 00:00:00pages
87-90issue
1eissn
1753-0393issn
1753-0407journal_volume
12pub_type
信件abstract:BACKGROUND:The aims of the present study were to examine the association of cigarette smoking and alcohol consumption with impaired β-cell function in Chinese men, particularly the interaction of smoking and alcohol consumption on impaired insulin secretion. METHODS:A population-based cross-sectional study was perform...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12314
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to investigate whether the therapeutic efficacy of acarbose and metformin is correlated with baseline HbA1c levels in Chinese patients with newly diagnosed type 2 diabetes mellitus (T2DM). METHODS:Data for 711 subjects were retrieved from the MARCH (Metformin and AcaRbose in...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12337
更新日期:2016-07-01 00:00:00
abstract::Diabetes mellitus is a metabolic disease with a considerable impact on healthcare owing to its increased prevalence and high mortality rate. Structural, morphological, and physiological changes in each of the ocular components have been described in detail. Autofluorescence has been described as a good indicator of me...
journal_title:Journal of diabetes
pub_type: 杂志文章,评审
doi:10.1111/1753-0407.12423
更新日期:2016-09-01 00:00:00
abstract::Observations from clinical studies suggest that low serum levels of testosterone in men are often associated with obesity, insulin resistance, and metabolic compromise. Indeed, the clinical symptoms of late-onset hypogonadism are markedly similar to those of Type 2 diabetes mellitus (T2DM) and metabolic syndrome, and ...
journal_title:Journal of diabetes
pub_type: 杂志文章,评审
doi:10.1111/j.1753-0407.2010.00085.x
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:Liver X receptors (LXRs) including LXRα and LXRβ are members of the nuclear hormone receptor superfamily of ligand activated transcription factors, which serve as lipid sensors to regulate expression of genes controlling many aspects of cholesterol and fatty acid metabolism. The liver is the central organ in...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12081
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:To analyze the glycemic response of Indian patients with type2 diabetes mellitus (T2DM) to combination therapy with vildagliptin and metformin and compare our data with those of clinical trials. METHODS:In a retrospective study of the hospital database, the glycemic control of 280 patients with T2DM who wer...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12078
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Although niacin often has beneficial effects on the lipoprotein profile, flushing is an untoward effect associated with its use. Aspirin can only reduce the flushing response by 30-40%. Thus, the aim of the present study was to investigate the mechanisms of niacin-induced flushing, with and without aspirin, ...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2012.00216.x
更新日期:2013-03-01 00:00:00
abstract:BACKGROUND:Women with previous gestational diabetes mellitus (pGDM) are at increased risk of developing type 2 diabetes later in life. The aim of this study was to determine if circulating levels of metabolic hormones 12 weeks following a GDM pregnancy are associated with an increased risk of type 2 diabetes 8-10 years...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12209
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Mitogen-inducible gene 6 (Mig-6) has an important role in the regulation of cholesterol homeostasis and bile acid synthesis. However, the physiological functions of Mig-6 in the liver remain poorly understood. METHODS:To investigate Mig-6 functioning in the liver, we used conditionally ablated Mig-6 using t...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12261
更新日期:2016-01-01 00:00:00
abstract::Skin autofluorescence is increased in diabetes, rises with age, and predicts diabetes-related complications. Exposure to secondhand smoke, because one or more family members are smokers, further increases skin autofluorescence in children and young adults with type 1 diabetes. Elimination of passive smoking should be ...
journal_title:Journal of diabetes
pub_type: 信件
doi:10.1111/1753-0407.12498
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:A1c, a surrogate measure of glycemic control, is known to have a strong linear correlation with mean plasma glucose (MPG) when analyzed in populations of patients. However, clinically significant intersubject variability in this relationship exists, which suggests that A1c measurements may not reflect actual...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2010.00066.x
更新日期:2010-06-01 00:00:00
abstract:OBJECTIVE:Dipeptidyl peptidase-4 (DPP-4) is responsible for degradation of glucagon-like peptide 1 (GLP-1) and gastric inhibitory polypeptide (GIP), the endogenous incretins that stimulate glucose-dependent insulin secretion. The objective was to evaluate preclinical profile of a novel DPP-4 inhibitor ZYDPLA1. METHODS...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12233
更新日期:2015-09-01 00:00:00
abstract::Adenosine triphosphate (ATP) synthesis and release in mitochondria play critical roles in regulating insulin secretion in pancreatic β cells. Mitochondrial dysfunction is mainly characterized by a decrease in ATP production, which is a central event in the progression of pancreatic β cell dysfunction and diabetes. ATP...
journal_title:Journal of diabetes
pub_type: 杂志文章,评审
doi:10.1111/1753-0407.12098
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:Some reports suggest that concentrations of vitamin D are inversely, whereas concentrations of parathyroid hormone (PTH) are directly, associated with prevalent metabolic syndrome. Because of lingering uncertainty about these associations, we examined the cross-sectional associations between serum concentrat...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2009.00046.x
更新日期:2009-12-01 00:00:00
abstract::Glucagon-like peptide-1 (GLP-1) is the primary incretin hormone secreted from the intestine upon uptake of food to stimulate insulin secretion from pancreatic β-cells. GLP-1 exerts its effects by binding to its G-protein coupled receptors and subsequently activating adenylate cyclase, leading to generation of cyclic a...
journal_title:Journal of diabetes
pub_type: 杂志文章,评审
doi:10.1111/1753-0407.12161
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Asia is experiencing a type 2 diabetes epidemic, but prevalence differs by ethnicity and level of socioeconomic development. Singapore and Mauritius have implemented comprehensive campaigns to address this public health problem. We compared diabetes and obesity prevalence trends among Chinese and South Asian...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12497
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Obesity and shorter telomeres increase the risk for diabetes complications and mortality. However, the relationship between obesity and telomere length in diverse Asian populations with type 2 diabetes (T2D) is not well understood. This study examined the association of baseline and changes in obesity indice...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12864
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Type 2 diabetes mellitus (T2DM) treatment generally requires multiple antihyperglycemic agents. When diet, exercise, and treatment with sulfonylurea and metformin do not achieve glycemic goals, several options are available. The present study evaluated the efficacy and tolerability of sitagliptin 100 mg/day ...
journal_title:Journal of diabetes
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/1753-0407.12351
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to assess the quality of diabetes care and characteristics of the healthcare system in underdeveloped rural mountain areas of western China. METHODS:Questionnaires were used to collect data from 288 diabetic patients with a multistage cluster sampling method in Zhongjiang Co...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12433
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:An increase in the prevalence of type 2 diabetes mellitus occurs in immigrants from developing regions to Western countries. However, the dynamics of these transitions in relation to the duration of residence in the new environment are not clearly defined. METHODS:Data concerning cardiovascular risk factors...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12215
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:G protein-coupled receptor kinase-2 (GRK2) has been shown as a key regulator of cardiac function, and the myocardial GRK2 levels are mirrored by the levels in peripheral blood mononuclear cells (PBMCs). In this study, we evaluated the myocardial and PBMCs GRK2 levels in early diabetic cardiomyopathy (DCM). ...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12991
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:To investigate the effect of hydroxypropyl methylcellulose (HPMC) on weight loss and metabolic disorders associated with obesity using a high-fat diet-induced obese mouse model under a high-fat diet regimen. METHODS: Obese male C57BL/6J (B6) mice were fed either a high-fat (60% kcal), low-fat (10% kcal), or...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2011.00118.x
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:The association between dental caries and metabolic syndrome (MetS) is inconsistent. The aim of the present study was to assess the relationship between dental caries and MetS and its components in a middle-aged Chinese population. METHODS:A cross-sectional analysis was performed of 13 998 participants aged...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12424
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Type 1 diabetes (T1D) is an autoimmune disease in which pancreatic β-cells are destroyed by infiltrating immune cells. Bilateral cooperation of pancreatic β-cells and immune cells has been proposed in the progression of T1D, but as yet no systems study has investigated this possibility. The aims of the study...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.12483
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Glucagon-like peptide-1 (GLP-1) and its stable analogue exendin-4 maintain glucose homeostasis by modulating insulin secretion from pancreatic β-cells and controlling hepatic glucose output. Glucokinase (GK), by catalysing the first step in glycolysis, plays an important role in glucose-stimulated insulin se...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2012.00193.x
更新日期:2012-12-01 00:00:00
abstract:BACKGROUND:There is little information on medication use, trends across time, and the impact of guidelines on appropriate use of antidiabetic drugs in participants with type 2 diabetes mellitus (T2DM) with chronic kidney disease (CKD). METHODS:A cross-sectional analysis of the National Health and Nutrition Examination...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.13003
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:In addition to its glucoregulatory actions, exendin-4, a stable glucagon-like peptide-1 receptor agonist, exhibits protective effects in the pancreas and anti-obesity effects. Suitable combination treatment with other anti-obesity or pancreas protective agents would be an effective approach to optimize these...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2012.00227.x
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:This meta-analysis was performed to quantitatively evaluate the dose-response association between obstructive sleep apnea (OSA) and risk of type 2 diabetes mellitus (T2DM). METHODS:PubMed, Embase, and Web of Science were searched up to 12 December 2018 for articles that assessed the OSA-T2DM association. Ra...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/1753-0407.13017
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Supervised treadmill exercise is the recommended therapy for peripheral arterial disease (PAD) patients with intermittent claudication (IC). However, most PAD patients do not exhibit typical symptoms of IC. The aim of the present study was to explore the efficacy and safety of intensive walking exercise in P...
journal_title:Journal of diabetes
pub_type: 杂志文章,meta分析,评审
doi:10.1111/1753-0407.12304
更新日期:2016-05-01 00:00:00
abstract::Islet transplantation is an attractive concept for the treatment of Type 1 diabetes because of its potential high efficacy and minimal invasion to patients. The treatment may effectively control blood glucose for brittle Type 1 diabetes, resulting in a marked reduction in hypoglycemic episodes and improvements in HbA1...
journal_title:Journal of diabetes
pub_type: 杂志文章
doi:10.1111/j.1753-0407.2009.00048.x
更新日期:2010-03-01 00:00:00