Abstract:
:Pancreatic cancer remains one of the deadliest cancers in the world, as a consequence of late diagnosis, early metastasis and limited response to chemotherapy, under which conditions the potential mechanism of pancreatic cancer progression requires further study. Exosomes are membrane vesicles which are important in the progression, metastasis and chemoresistance in pancreatic cancer. Additionally, they have been verified to be potential as biomarkers, targets and drug carriers for pancreatic cancer treatment. Thus, studying the role of exosomes in pancreatic cancer is significant. This paper focuses on the role of exosomes in the proliferation, metastasis and chemoresistance, as well as their potential applications for pancreatic cancer.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Lan B,Zeng S,Grützmann R,Pilarsky Cdoi
10.3390/ijms20184332subject
Has Abstractpub_date
2019-09-04 00:00:00issue
18issn
1422-0067pii
ijms20184332journal_volume
20pub_type
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