Abstract：
:In this study, nanoparticle-incorporated nanofiber-covered yarns were prepared using a custom-made needle-free electrospinning system. The ultimate goal of this work was to prepare functional nanofibrous surfaces with antibacterial properties and realize high-speed production. As antibacterial agents, we used various amounts of copper oxide (CuO) and vanadium (V) oxide (V2O5) nanoparticles (NPs). Three yarn preparation speeds (100 m/min, 150 m/min, and 200 m/min) were used for the nanofiber-covered yarn. The results indicate a relationship between the yarn speed, quantity of NPs, and antibacterial efficiency of the material. We found a higher yarn speed to be associated with a lower reduction in bacteria. NP-loaded nanofiber yarns were proven to have excellent antibacterial properties against Gram-negative Escherichia coli (E. coli). CuO exhibited a greater inhibition and bactericidal effect against E. coli than V2O5. In brief, the studied samples are good candidates for use in antibacterial textile surface applications, such as wastewater filtration. As greater attention is being drawn to this field, this work provides new insights regarding the antibacterial textile surfaces of nanofiber-covered yarns.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Yalcinkaya F,Komarek Mdoi
10.3390/ijms20174317subject
Has Abstractpub_date
2019-09-03 00:00:00issue
17issn
1422-0067pii
ijms20174317journal_volume
20pub_type
杂志文章abstract：:Wheat amylase trypsin inhibitors (ATIs) represent a common dietary protein component of gluten-containing cereals (wheat, rye, and barley). They act as toll-like receptor 4 ligands, and are largely resistant to intestinal proteases, eliciting a mild inflammatory response within the intestine after oral ingestion. Impo...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21176288
更新日期：2020-08-31 00:00:00
abstract：:Psoriasis vulgaris is an immune-mediated inflammatory skin disease. Although acitretin is a widely used synthetic retinoid for moderate to severe psoriasis, little is known about patients' genetics in response to this drug. In this study, 179 patients were enrolled in either the discovery set (13 patients) or replicat...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms18020295
更新日期：2017-01-29 00:00:00
abstract：:Heme oxygenase 1 (HO-1) and carbon monoxide were shown to normalize oxidative stress and inflammatory reactions induced by neuropathic pain in the central nervous system, but their effects in the locus coeruleus (LC) of animals with peripheral inflammation and their interaction with nitric oxide are unknown. In wild-t...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20092211
更新日期：2019-05-05 00:00:00
abstract：:It has been confirmed that alternatively activated macrophages (M2) participate in tissue remodeling and fibrosis occurrence, but the effect of M2 on peritoneal fibrosis related to peritoneal dialysis (PD) hasn't been elucidated. This study was therefore conducted to assess the association between M2 and peritoneal fi...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms140510369
更新日期：2013-05-17 00:00:00
abstract：:5-Fluorouracil (5-FU) is an important chemotherapeutic agent for the systemic treatment of colorectal cancer (CRC), but its effectiveness against CRC is limited by increased 5-FU resistance caused by the hypoxic tumor microenvironment. The purpose of our study was to assess the feasibility of using quinacrine (QC) to ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20184366
更新日期：2019-09-05 00:00:00
abstract：:The gadolinium-based nanoagent named AGuIX® is a unique radiosensitizer and contrast agent which improves the performance of radiotherapy and medical imaging. Currently tested in clinical trials, AGuIX® is administrated to patients via intravenous injection. The presence of nanoparticles in the blood stream may induce...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21134673
更新日期：2020-06-30 00:00:00
abstract：:Age-related hearing loss (ARHL) is an irreversible, progressive neurodegenerative disorder and is presently untreatable. Previous studies using animal models have suggested mitochondrial damage and programmed cell death to be involved with ARHL. Thus, we further investigated the pathophysiologic role of mitochondria a...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
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更新日期：2020-04-03 00:00:00
abstract：:Spontaneous beating of the heart pacemaker, the sinoatrial node, is generated by sinoatrial node cells (SANC) and caused by gradual change of the membrane potential called diastolic depolarization (DD). Submembrane local Ca2+ releases (LCR) from sarcoplasmic reticulum (SR) occur during late DD and activate an inward N...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms19082173
更新日期：2018-07-25 00:00:00
abstract：:The aim of this review article is to introduce the reader to the state-of-the-art of the contribution that proteomics and metabolomics sciences are currently providing for cystic fibrosis (CF) research: from the understanding of cystic fibrosis transmembrane conductance regulator (CFTR) biology to biomarker discovery ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms21155439
更新日期：2020-07-30 00:00:00
abstract：:RNA isolated from fixed and paraffin-embedded tissues is widely used in biomedical research and molecular pathology for diagnosis. In the present study, we have set-up a method based on high performance liquid chromatography (HPLC) to investigate the effects of different fixatives on RNA. By the application of the pre...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21207540
更新日期：2020-10-13 00:00:00
abstract：:Deficits in plasma membrane repair have been identified in dysferlinopathy and Duchenne Muscular Dystrophy, and contribute to progressive myopathy. Although Facioscapulohumeral Muscular Dystrophy (FSHD) shares clinicopathological features with these muscular dystrophies, it is unknown if FSHD is characterized by plasm...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
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更新日期：2020-08-04 00:00:00
abstract：:NAC (no apical meristem (NAM), Arabidopsis thaliana transcription activation factor (ATAF1/2) and cup shaped cotyledon (CUC2)) transcription factors play crucial roles in plant development and stress responses. Nevertheless, to date, only a few reports regarding stress-related NAC genes are available in Malus baccata(...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21041198
更新日期：2020-02-11 00:00:00
abstract：:Both long-term undernutrition and overnutrition disturb metabolic balance, which is mediated partially by the action of two adipokines, leptin and resistin (RSTN). In this study, we manipulated the diet of ewes to produce either a thin (lean) or fat (fat) body condition and investigated how RSTN affects endocrine and ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21124238
更新日期：2020-06-14 00:00:00
abstract：:That the nervous system is the main target of lead (Pb) has long been considered an established fact until recent evidence has linked the Pb effect on the immune system to the toxic effects of Pb on the nervous system. In this paper, we present recent literature reports on the effect of Pb on the inflammatory processe...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms17122140
更新日期：2016-12-19 00:00:00
abstract：:The importance of mitogen-activated protein kinases (MAPK) in human pathology is underlined by the relevance of abnormalities of MAPK-related signaling pathways to a number of different diseases, including inflammatory disorders and cancer. One of the key events in MAPK signaling, especially with respect to pro-prolif...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms21030938
更新日期：2020-01-31 00:00:00
abstract：:Alternative splicing plays an important role in numerous cellular processes and aberrant splice decisions are associated with cancer. Although some studies point to a regulation of alternative splicing and its effector mechanisms in a time-dependent manner, the extent and consequences of such a regulation remains poor...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20051182
更新日期：2019-03-08 00:00:00
abstract：:In this study, we optimized the geometry and composition of additive-manufactured pedicle screws. Metal powders of titanium-aluminum-vanadium (Ti-6Al-4V) were mixed with reactive glass-ceramic biomaterials of bioactive glass (BG) powders. To optimize the geometry of pedicle screws, we applied a novel numerical approac...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21207438
更新日期：2020-10-09 00:00:00
abstract：:Alpha-synuclein is considered the major pathological protein associated with Parkinson's disease, but there is still no effective immunotherapy which targets alpha-synuclein. In order to create a safer and more effective therapy against PD, we are targeting an epitope of alpha-synuclein rather than full-length alpha-s...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20092338
更新日期：2019-05-11 00:00:00
abstract：:Multiple sclerosis is a potentially debilitating disease of the central nervous system. A concerted program of research by many centers around the world has consistently demonstrated the importance of the immune system in its pathogenesis. This knowledge has led to the formal testing of a number of therapeutic agents ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms131012665
更新日期：2012-10-04 00:00:00
abstract：:Wilms tumor protein-1 (WT1) is an attractive target for adoptive T-cell therapy due to its expression in solid tumors and hematologic malignancies. However, T cells recognizing WT1 occur in low frequencies in the peripheral blood of healthy donors, limiting potential therapeutic possibilities. Tin mesoporphyrin (SnMP)...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20030482
更新日期：2019-01-23 00:00:00
abstract：:It has been shown that saturated fatty acids (FAs) have a detrimental effect on pancreatic β-cells function and survival, leading to apoptosis, whereas unsaturated FAs are well tolerated and are even capable of inhibiting the pro-apoptotic effect of saturated FAs. Molecular mechanisms of apoptosis induction and regula...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms18112313
更新日期：2017-11-02 00:00:00
abstract：:The lack of effective Alzheimer's disease treatment is becoming a challenge for researchers and prompts numerous attempts to search for and develop better therapeutic solutions. Compounds that affect several routes of the neurodegeneration cascade leading to the development of disease are of particular interest. An ex...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21082749
更新日期：2020-04-15 00:00:00
abstract：:Oxymatrine (OMT) is a strong immunosuppressive agent that has been used in the clinic for many years. In the present study, by using plaque inhibition, luciferase reporter plasmids, qRT-PCR, western blotting, and ELISA assays, we have investigated the effect and mechanism of OMT on influenza A virus (IAV) replication ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms19040965
更新日期：2018-03-23 00:00:00
abstract：:Staphylococcus aureus is able to rapidly develop mechanisms of resistance to various drugs and to form strong biofilms, which makes it necessary to develop new antibacterial drugs. The essential oil of Melaleuca alternifolia is used as an antibacterial, a property believed to be mainly due to the presence of terpinen-...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21124531
更新日期：2020-06-25 00:00:00
abstract：:This experiment aimed to investigate the effects of the chitosan (CTS) and water-soluble chitosan (WSC) microspheres on plasma lipids in male Sprague-Dawley rats fed with high-fat diets. CTS microspheres and WSC microspheres were prepared by the spray-drying technique. Scanning electron microscopy (SEM) micrographs s...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms14024174
更新日期：2013-02-19 00:00:00
abstract：:Ethanol abuse is a common issue in individuals with sedentary lifestyles, unbalanced diets, and metabolic syndrome. Both ethanol abuse and metabolic syndrome have negative impacts on the central nervous system, with effects including cognitive impairment and brain oxidative status deterioration. The combined effects o...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms22020807
更新日期：2021-01-15 00:00:00
abstract：:The identification of molecules that can reliably detect the presence of a tumor or predict its behavior is one of the biggest challenges of research in cancer biology. Biological fluids are intriguing mediums, containing many molecules that express the individual health status and, accordingly, may be useful in estab...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms17040593
更新日期：2016-04-19 00:00:00
abstract：:The molecular pathology of diseases seen from the mitochondrial axis has become more complex with the progression of research. A variety of factors, including the failure of mitochondrial dynamics and quality control, have made it extremely difficult to narrow down drug discovery targets. We have identified MITOL (mit...
journal_title：International journal of molecular sciences
pub_type： 杂志文章,评审
doi：10.3390/ijms21113781
更新日期：2020-05-27 00:00:00
abstract：:Fat deposition, which influences pork production, meat quality and growth efficiency, is an economically important trait in pigs. Numerous studies have demonstrated that stearoyl-CoA desaturase (SCD), a key enzyme that catalyzes the conversion of saturated fatty acids into monounsaturated fatty acids, is associated wi...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms21072446
更新日期：2020-04-01 00:00:00
abstract：:The largest group of deubiquitinases-ubiquitin-specific proteases (UBPs)-perform extensive and significant roles in plants, including the regulation of development and stress responses. A comprehensive analysis of UBP genes has been performed in Arabidopsis thaliana, but no systematic study has been conducted in moso ...
journal_title：International journal of molecular sciences
pub_type： 杂志文章
doi：10.3390/ijms20174309
更新日期：2019-09-03 00:00:00
