Abstract：
:The capacity of two homoserine lactones to stimulate the marine bacteria Pseudoalteromonas ulvae (TC14 strain) for its capacity to form a biofilm when exposed to a potent antibiofilm compound AS162 is reported. Effective concentrations (EC50) of AS162 at 24 h, 48 h, and 72 h were, respectively, of 4.3, 4.4, and 6.0 µM. When tested in combination with HSLs, results showed that quorum-sensing signal molecules 3-oxo-C6 and 3-oxo-C8 homoserine lactones do not act directly on the biofilm formation, but are able to interfere positively with AS162 to promote biofilm growth with EC50 ranging from 30 to 50 µM. The same results were obtained with two other marine bacterial strains: Pseudoalteromonas lipolytica TC8 and Paracoccus sp. 4M6. These findings suggest that HSLs can significantly affect the biocidal sensitivity of marine bacteria to antifouling agents.
journal_name
3 Biotechjournal_title
3 Biotechauthors
Gozoua E,Koffi-Nevry R,Blache Ydoi
10.1007/s13205-019-1866-6subject
Has Abstractpub_date
2019-09-01 00:00:00pages
338issue
9eissn
2190-572Xissn
2190-5738pii
1866journal_volume
9pub_type
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