Drug Screening for Discovery of Broad-spectrum Agents for Soil-transmitted Nematodes.

abstract：:Methods and mechanisms for improvement of photocatalytic activity, are important and popular research topics for renewable energy production and waste water treatment. Here, we demonstrate a facile laser drilling method for engineering well-aligned pore arrays on magnetron-sputtered WS2 nanofilms with increased active...

journal_title：Scientific reports

authors： Ma S,Zeng L,Tao L,Tang CY,Yuan H,Long H,Cheng PK,Chai Y,Chen C,Fung KH,Zhang X,Lau SP,Tsang YH

更新日期：2017-06-09 00:00:00

abstract：:Novel amorphous iron hydrides (AIHs) are synthesized for the first time under ambient conditions by employing novel "quiescent reaction", without stirring for mixing solutions, during a conventional aqueous reduction-precipitation process. The kind and morphology of AIHs are dependent on the processing condition, wher...

journal_title：Scientific reports

authors： Taguchi K,Shinozaki K,Okumura H,Michioka C,Yoshimura K,Ishihara KN

更新日期：2020-04-10 00:00:00

abstract：:Infantile hemangioma is the most common benign tumor in infants. Many studies have confirmed that basic fibroblast growth factor (bFGF) and its key receptor FGFR1 are highly expressed in hemangioma. Moreover, several miRNAs can regulate angiogenesis. In this regard, miR-424 often plays a role as tumor suppressor gene....

journal_title：Scientific reports

authors： Yang L,Dai J,Li F,Cheng H,Yan D,Ruan Q

更新日期：2017-09-19 00:00:00

abstract：:The use of impedance-based label free cell analysis is increasingly popular and has many different applications. Here, we report that a real-time cell analyzer (RTCA) can be used to study the stimulation of Natural Killer (NK) cells. Engagement of NK cells via plate-bound antibodies directed against different activati...

journal_title：Scientific reports

authors： Fasbender F,Watzl C

更新日期：2018-03-21 00:00:00

abstract：:Neurofeedback is a strong direct training method for brain function, wherein brain activity patterns are measured and displayed as feedback, and trainees try to stabilize the feedback signal onto certain desirable states to regulate their own mental states. Here, we introduce a novel neurofeedback method, using the mi...

journal_title：Scientific reports

authors： Chang M,Iizuka H,Naruse Y,Ando H,Maeda T

更新日期：2014-10-24 00:00:00

abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

journal_title：Scientific reports

authors： Lee DB,Kim JM,Seok JH,Lee JH,Jo JD,Mun JY,Conrad C,Coe J,Nelson G,Hogue B,White TA,Zatsepin N,Weierstall U,Barty A,Chapman H,Fromme P,Spence J,Chung MS,Oh CH,Kim KH

更新日期：2018-04-17 00:00:00

abstract：:Distance, environmental heterogeneity and local adaptation can strongly influence population structure and connectivity. Understanding how these factors shape the genomic landscape of threatened species is a major goal in conservation genomics and wildlife management. Herein, we use thousands (6,859) of single nucleot...

journal_title：Scientific reports

authors： Sánchez-Ramírez S,Rico Y,Berry KH,Edwards T,Karl AE,Henen BT,Murphy RW

更新日期：2018-07-25 00:00:00

abstract：:Multilevel severe compressive myelopathy is a challenging disorder for the surgeons, the aim of this study is to assess the efficacy and safety of a newly designed ultrasonic burr as an assistant tool to the ultrasonic scalpel in laminectomy for this disease. This is a retrospective comparative study, the included sub...

journal_title：Scientific reports

authors： Chen Y,Chang Z,Yu X,Song R,Huang W

更新日期：2018-03-05 00:00:00

abstract：:Nearly half of the world's population obtains its daily calories from rice grains, which lack or have insufficient levels of essential micronutrients. The deficiency of micronutrients vital for normal growth is a global health problem, and iron, zinc and vitamin A deficiencies are the most prevalent ones. We developed...

journal_title：Scientific reports

authors： Singh SP,Gruissem W,Bhullar NK

更新日期：2017-07-31 00:00:00

abstract：:An important property of spin-torque nano-oscillators (STNOs) is their ability to produce a frequency modulated (FM) signal, which is very critical for communication applications. We here demonstrate a novel single sideband (SSB) modulation phenomenon using a magnetic tunnel junction (MTJ)-based STNO, which saves tran...

journal_title：Scientific reports

authors： Sharma R,Sisodia N,Iacocca E,Awad AA,Åkerman J,Muduli PK

更新日期：2017-10-18 00:00:00

abstract：:The National Lung Screening Trial (NLST) demonstrated that screening with low-dose computed tomography (LDCT) is associated with a 20% reduction in lung cancer mortality. One potential limitation of LDCT screening is overdiagnosis of slow growing and indolent cancers. In this study, peritumoral and intratumoral radiom...

journal_title：Scientific reports

authors： Pérez-Morales J,Tunali I,Stringfield O,Eschrich SA,Balagurunathan Y,Gillies RJ,Schabath MB

更新日期：2020-06-29 00:00:00

abstract：:Histone lysine methyltransferases (KMTs) play an important role in epigenetic gene regulation and have emerged as promising targets for drug discovery. However, the scope and limitation of KMT catalysis on substrates possessing substituted lysine side chains remain insufficiently explored. Here, we identify new unnatu...

journal_title：Scientific reports

authors： Al Temimi AHK,Merx J,van Noortwijk CJ,Proietti G,Buijs R,White PB,Rutjes FPJT,Boltje TJ,Mecinović J

更新日期：2020-12-09 00:00:00

abstract：:Monitoring of disease/therapeutic conditions is an important application of circulating tumor DNA (ctDNA). We devised numerical indices, based on ctDNA dynamics, for therapeutic response and disease progression. 52 lung cancer patients subjected to the EGFR-TKI treatment were prospectively collected, and ctDNA levels ...

journal_title：Scientific reports

authors： Kato K,Uchida J,Kukita Y,Kumagai T,Nishino K,Inoue T,Kimura M,Oba S,Imamura F

更新日期：2016-07-06 00:00:00

abstract：:Recent studies have established that single nucleotide polymorphisms are sufficient to build accurate predictive models of gene expression. Gamazon, et al., found that gene expression values predicted from cis neighborhood SNPs show statistical association with disease status. In this work, we remove the cis neighborh...

journal_title：Scientific reports

authors： Vervier K,Michaelson JJ

更新日期：2016-12-20 00:00:00

abstract：:The leaf venation architecture is an ideal, highly structured and efficient irrigation system in plant leaves. Leaf vein density (LVD) and vein thickness are the two major properties of this system. Leaf laminae carry out photosynthesis to harvest the maximum biological yield. It is still unknown whether the LVD and/o...

journal_title：Scientific reports

authors： Tabassum MA,Zhu G,Hafeez A,Wahid MA,Shaban M,Li Y

更新日期：2016-11-16 00:00:00

abstract：:Personal values developed in adolescence may influence mental health and well-being over the life course. Using data from 684 respondents in the Youth Development Study (61.9% of respondents in the baseline survey), we explored the effects of work values at ages 14-15 on positive and negative emotions, as well as psyc...

journal_title：Scientific reports

authors： Fukasawa M,Watanabe K,Nishi D,Kawakami N

更新日期：2020-08-11 00:00:00

abstract：:The identification of clinically-relevant early diagnostic and prognostic protein biomarkers is essential to maximize therapeutic efficacy and prevent cancer progression. The aim of the current study is to determine whether aberrant plasma protein profile can be applied as a surrogate tool for early diagnosis of bladd...

journal_title：Scientific reports

authors： Nedjadi T,Benabdelkamal H,Albarakati N,Masood A,Al-Sayyad A,Alfadda AA,Alanazi IO,Al-Ammari A,Al-Maghrabi J

更新日期：2020-07-03 00:00:00

abstract：:Polystyrene sulfonate (PSS), a strong polyelectrolyte, was used to prepare red photoluminescent PSS-penicillamine (PA) copper (Cu) nanoclusters (NC) aggregates, which displayed high selectivity and sensitivity to the detection of hydrogen sulfide (H2S). The size of the PSS-PA-Cu NC aggregates could be readily controll...

journal_title：Scientific reports

authors： Chen PC,Li YC,Ma JY,Huang JY,Chen CF,Chang HT

更新日期：2016-04-26 00:00:00

abstract：:By using highly aligned carbon nanotube (CNT) sheets of excellent optical transmittance and mechanical stretchability as both the current collector and active electrode, high-performance transparent and stretchable all-solid supercapacitors with a good stability were developed. A transmittance up to 75% at the wavelen...

journal_title：Scientific reports

authors： Chen T,Peng H,Durstock M,Dai L

更新日期：2014-01-09 00:00:00

abstract：:The increasing demand for healthy baked goods boosted studies on sourdough microbiota with beneficial metabolic traits, to be used as potential functional starters. Here, 139 yeasts isolated from cereal-based fermented foods were in vitro characterized for their phytase and antioxidant activities. The molecular charac...

journal_title：Scientific reports

authors： Palla M,Blandino M,Grassi A,Giordano D,Sgherri C,Quartacci MF,Reyneri A,Agnolucci M,Giovannetti M

更新日期：2020-07-30 00:00:00

abstract：:A toolbox for the quantum simulation of polarons in ultracold atoms is presented. Motivated by the impressive experimental advances in the area of ultracold atomic mixtures, we theoretically study the problem of ultracold atomic impurities immersed in a Bose-Einstein condensate mixture (BEC). The coupling between impu...

journal_title：Scientific reports

authors： Compagno E,De Chiara G,Angelakis DG,Palma GM

更新日期：2017-05-24 00:00:00

abstract：:HIV-1 env sequencing enables predictions of viral coreceptor tropism and phylogenetic investigations of transmission events. The aim of the study was to estimate the contribution of non-R5 strains to the viral spread in Poland. Partial proviral env sequences were retrieved from baseline blood samples of patients with ...

journal_title：Scientific reports

authors： Smoleń-Dzirba J,Rosińska M,Kruszyński P,Janiec J,Cycoń M,Bratosiewicz-Wąsik J,Beniowski M,Bociąga-Jasik M,Jabłonowska E,Szetela B,Wąsik TJ

更新日期：2019-03-21 00:00:00

abstract：:Patients with advanced ovarian cancer develop recurrence despite initial treatment response to standard treatment of surgery and intravenous/intraperitoneal (IP) chemotherapy, partly due to a limited peritoneal exposure time of chemotherapeutics. Paclitaxel-loaded genipin-crosslinked gelatin microspheres (PTX-GP-MS) a...

journal_title：Scientific reports

authors： De Clercq K,Xie F,De Wever O,Descamps B,Hoorens A,Vermeulen A,Ceelen W,Vervaet C

更新日期：2019-10-16 00:00:00

abstract：:Angiogenin (hANG), a member of the Ribonuclease A superfamily has angiogenic, neurotrophic and neuroprotective activities. Mutations in hANG have been found in patients with Amyotrophic lateral sclerosis (ALS). The zebrafish (Danio rerio) rnasel-1, 2 and 3 are orthologues of hANG and of these only Rnasel-1 and Rnasel-...

journal_title：Scientific reports

authors： Ferguson R,Holloway DE,Chandrasekhar A,Acharya KR,Subramanian V

更新日期：2019-02-01 00:00:00

abstract：:Pt/K2CO3/MgAlOx-reduced graphene oxide (Pt/K/MgAlOx-rGO) hybrids were synthesized, characterized and tested as a promising NOx storage and reduction (NSR) catalyst. Mg-Al layered double hydroxides (LDHs) were grown on rGO via in situ hydrothermal crystallization. The structure and morphology of samples were thoroughly...

journal_title：Scientific reports

authors： Mei X,Yan Q,Lu P,Wang J,Cui Y,Nie Y,Umar A,Wang Q

更新日期：2017-02-16 00:00:00

abstract：:Lung adenosquamous cell carcinomas (ASCs) is a rare variant of NSCLC with a poorer prognosis and fewer treatment option than the more common variants. PD-L1 expression is reported to be the predictor of clinical response in trials of NSCLC. In our study, PD-L1 expression was evaluated via immunohistochemistry using a ...

journal_title：Scientific reports

authors： Shi X,Wu S,Sun J,Liu Y,Zeng X,Liang Z

更新日期：2017-04-07 00:00:00

abstract：:Tolmetin is a non-steroidal anti-inflammatory drug being used to decrease the level of hormones which are the reasons for pain, swelling, tiredness, and stiffness for osteoarthritis and rheumatoid arthritis cases. We evaluated its solubility in supercritical carbon dioxide (SC-CO2) with the aim of drug nanonization, c...

journal_title：Scientific reports

authors： Pishnamazi M,Zabihi S,Sarafzadeh P,Borousan F,Marjani A,Pelalak R,Shirazian S

更新日期：2020-11-11 00:00:00

abstract：:Study aimed to assess long-term bowel function in patients who underwent low anterior resection for cancer five and more years ago. Patients who underwent low anterior resection for rectal cancer from 2010 to 2015 at National Cancer Institute were prospectively included in our study. They were interviewed using low an...

journal_title：Scientific reports

authors： Dulskas A,Kavaliauskas P,Pilipavicius L,Jodinskas M,Mikalonis M,Samalavicius NE

更新日期：2020-07-17 00:00:00

abstract：:We aim to evaluate the association of systolic and diastolic blood pressure (SBP and DBP) with estimated urinary sodium (Na) and potassium(K) excretions, and their gram-to-gram Na/K ratio across various salt-diet regions during 2005-2009 in China. A prospective cohort study was conducted to recruit 46,285 participants...

journal_title：Scientific reports

authors： Yin L,Deng G,Mente A,Sun Y,Liu X,Zhang X,Wang X,Wang Y,Bo J,Chen H,Liu X,Gao N,Bai X,Rangarajan S,Li W

更新日期：2018-04-30 00:00:00

abstract：:Microtubule affinity regulating kinase 4 (MARK4) becomes a unique anti-cancer drug target as its overexpression is responsible for different types of cancers. In quest of novel, effective MARK4 inhibitors, some acridone derivatives were synthesized, characterized and evaluated for inhibitory activity against human MAR...

journal_title：Scientific reports

authors： Voura M,Khan P,Thysiadis S,Katsamakas S,Queen A,Hasan GM,Ali S,Sarli V,Hassan MI

更新日期：2019-02-08 00:00:00