Abstract:
BACKGROUND AND AIMS:We developed a system for computer-assisted diagnosis (CAD) for real-time automated diagnosis of precancerous lesions and early esophageal squamous cell carcinomas (ESCCs) to assist the diagnosis of esophageal cancer. METHODS:A total of 6473 narrow-band imaging (NBI) images, including precancerous lesions, early ESCCs, and noncancerous lesions, were used to train the CAD system. We validated the CAD system using both endoscopic images and video datasets. The receiver operating characteristic curve of the CAD system was generated based on image datasets. An artificial intelligence probability heat map was generated for each input of endoscopic images. The yellow color indicated high possibility of cancerous lesion, and the blue color indicated noncancerous lesions on the probability heat map. When the CAD system detected any precancerous lesion or early ESCCs, the lesion of interest was masked with color. RESULTS:The image datasets contained 1480 malignant NBI images from 59 consecutive cancerous cases (sensitivity, 98.04%) and 5191 noncancerous NBI images from 2004 cases (specificity, 95.03%). The area under curve was 0.989. The video datasets of precancerous lesions or early ESCCs included 27 nonmagnifying videos (per-frame sensitivity 60.8%, per-lesion sensitivity, 100%) and 20 magnifying videos (per-frame sensitivity 96.1%, per-lesion sensitivity, 100%). Unaltered full-range normal esophagus videos included 33 videos (per-frame specificity 99.9%, per-case specificity, 90.9%). CONCLUSIONS:A deep learning model demonstrated high sensitivity and specificity for both endoscopic images and video datasets. The real-time CAD system has a promising potential in the near future to assist endoscopists in diagnosing precancerous lesions and ESCCs.
journal_name
Gastrointest Endoscjournal_title
Gastrointestinal endoscopyauthors
Guo L,Xiao X,Wu C,Zeng X,Zhang Y,Du J,Bai S,Xie J,Zhang Z,Li Y,Wang X,Cheung O,Sharma M,Liu J,Hu Bdoi
10.1016/j.gie.2019.08.018subject
Has Abstractpub_date
2020-01-01 00:00:00pages
41-51issue
1eissn
0016-5107issn
1097-6779pii
S0016-5107(19)32187-Xjournal_volume
91pub_type
杂志文章abstract:BACKGROUND AND AIMS:Despite a paucity of women occupying leadership positions in academic medicine, studies have shown a higher ratio of female representation in the program director position compared with division chief in multiple specialties. This study aims to determine whether this trend exists in 3-year gastroent...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2017.01.019
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:Disposable biopsy forceps have been heavily marketed as cost-effective, convenient, and safer to use than conventional forceps. METHODS:In an attempt to define whether disposable or reusable biopsy forceps were cheaper to use, we prospectively evaluated the purchase price, number of uses, repair record, and...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(96)70252-3
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Dysplasia within sessile serrated polyps (SSPs) is difficult to detect and may be mistaken for an adenoma, risking incomplete resection of the background serrated tissue, and is strongly implicated in interval cancer after colonoscopy. The use of endoscopic imaging to detect dysplasia within SSPs ha...
journal_title:Gastrointestinal endoscopy
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doi:10.1016/j.gie.2017.06.031
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Placement of a pancreatic duct (PD) stent reduces post-ERCP pancreatitis rates in high-risk patients. Patients with suspected sphincter of Oddi dysfunction (SOD) who are found to have normal manometry results (SOM) are also at high risk for this complication. OBJECTIVE:Our purpose was to determine whether P...
journal_title:Gastrointestinal endoscopy
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doi:10.1016/j.gie.2007.06.022
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:Despite recent advances in cytology brush design, yield of endoscopic brush cytology in suspected pancreatic carcinoma remains low. METHODS:We prospectively evaluated 32 such patients by ERCP to analyze differences in yield based on anatomic location of the pancreatic stricture, and the role of concurrent b...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(96)70168-2
更新日期:1996-09-01 00:00:00
abstract::Guide wires have become an essential part of therapeutic biliary and pancreatic endoscopy. The Teflon-painted stainless steel wire still remains the standard guide wire. However, special situations call for the use of some of the more specialized guide wires mentioned in this article. The endoscopist needs to be famil...
journal_title:Gastrointestinal endoscopy
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doi:10.1016/s0016-5107(96)70262-6
更新日期:1996-01-01 00:00:00
abstract::We prospectively evaluated multiple physiologic parameters in 104 consecutive unselected patients undergoing elective colonoscopy. Changes observed during colonoscopy were then correlated with the type of anesthesia and level of sedation, position of the endoscope and presence of looping, existence of comorbid medical...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(90)70916-9
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Acute GI bleeding is a life-threatening complication of warfarin therapy. Acute GI bleeding in patients with an international normalized ratio of 4.0 or greater (supratherapeutic) is often attributed to trivial mucosal lesions. The aim of the study was to determine the frequency of potentially significant le...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:
更新日期:2003-09-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1996-10-01 00:00:00
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journal_title:Gastrointestinal endoscopy
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更新日期:2000-09-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 临床试验,杂志文章
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journal_title:Gastrointestinal endoscopy
pub_type: 临床试验,杂志文章
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更新日期:1997-02-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(97)70058-0
更新日期:1997-08-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2010.03.1126
更新日期:2010-09-01 00:00:00
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journal_title:Gastrointestinal endoscopy
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doi:10.1016/j.gie.2017.04.032
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Endoscopic detection of superficial squamous epithelial lesions of the pharynx has increased. OBJECTIVE:To clarify the association between macroscopic and histologic characteristics of intraepithelial pharyngeal neoplasias, and to evaluate the effectiveness of endoscopic submucosal dissection (ESD) for thei...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2012.07.032
更新日期:2012-12-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2006.09.018
更新日期:2007-07-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(90)71020-6
更新日期:1990-05-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Gastrointestinal endoscopy
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更新日期:2001-02-01 00:00:00
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journal_title:Gastrointestinal endoscopy
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更新日期:2016-12-01 00:00:00
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journal_title:Gastrointestinal endoscopy
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更新日期:2019-02-01 00:00:00
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journal_title:Gastrointestinal endoscopy
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doi:10.1016/s0016-5107(05)00561-4
更新日期:2005-07-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章,评审
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更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Peroral cholangioscopy (POC) provides direct visualization of the bile duct and facilitates diagnostic procedures and therapeutic intervention. The currently available mother-baby endoscope system is not widely used because of several limitations. Although direct cholangioscopy with an ultraslim upper endosc...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2008.11.019
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Photodynamic therapy appears to be effective in ablating high-grade dysplasia in Barrett's esophagus. Our aim was to identify the most effective and cost-effective strategy for managing high-grade dysplasia in Barrett's esophagus without associated endoscopically visible abnormalities. METHODS:By using deci...
journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(04)02167-4
更新日期:2004-11-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(99)70342-1
更新日期:1999-07-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/j.gie.2008.09.054
更新日期:2009-03-01 00:00:00
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journal_title:Gastrointestinal endoscopy
pub_type: 杂志文章
doi:10.1016/s0016-5107(85)71956-6
更新日期:1985-02-01 00:00:00