Abstract：
:Tic20 is an important translocon protein that plays a role in protein transport in the chloroplast. The sequence of Tic20 was determined in the lower brown alga Saccharina japonica. Structural analysis of SjTic20 revealed a noncanonical structure consisting of an N-terminal non-cyanobacterium-originated EF-hand domain (a helix-loop-helix structural domain) and a C-terminal cyanobacterium-originated Tic20 domain. Subcellular localization and transmembrane analysis indicated that SjTic20 featured an "M"-type Nin-Cin-terminal orientation, with four transmembrane domains in the innermost membrane of the chloroplast in the microalga Phaeodactylum tricornutum, and the EF-hand domain was entirely extruded into the chloroplast stroma. Our study provides information on the structure, localization, and topological features of SjTic20, and further functional analysis of SjTic20 in S. japonica is needed.
journal_name
Int J Mol Scijournal_title
International journal of molecular sciencesauthors
Chen Z,Wang X,Li S,Yao J,Shao Z,Duan Ddoi
10.3390/ijms20164000subject
Has Abstractpub_date
2019-08-16 00:00:00issue
16issn
1422-0067pii
ijms20164000journal_volume
20pub_type
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