Abstract:
:An amendment to this paper has been published and can be accessed via a link at the top of the paper.
journal_name
Nat Communjournal_title
Nature communicationsauthors
Tebo AG,Gautier Adoi
10.1038/s41467-019-11689-6subject
Has Abstractpub_date
2019-08-14 00:00:00pages
3730issue
1issn
2041-1723pii
10.1038/s41467-019-11689-6journal_volume
10pub_type
已发布勘误abstract::Nano-sized metal particles are attracting much interest in industrial and biomedical applications due to the recent progress and development of nanotechnology, and the surface-modifications by appropriate polymers are key techniques to stably express their characteristics. Herein, we applied cyclic poly(ethylene glyco...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-19947-8
更新日期:2020-11-30 00:00:00
abstract::Mechanical signals play many roles in cell and developmental biology. Several mechanotransduction pathways have been uncovered, but the mechanisms identified so far only address the perception of stress intensity. Mechanical stresses are tensorial in nature, and thus provide dual mechanical information: stress magnitu...
journal_title:Nature communications
pub_type: 杂志文章,评审
doi:10.1038/s41467-019-10207-y
更新日期:2019-05-29 00:00:00
abstract::Emerging evidence suggests that caveolin-1 (Cav1) is associated with pulmonary arterial hypertension. MURC (also called Cavin-4) is a member of the cavin family, which regulates caveolar formation and functions together with caveolins. Here, we show that hypoxia increased Murc mRNA expression in the mouse lung, and th...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12417
更新日期:2016-08-22 00:00:00
abstract::The serotonin transporter (SERT), a member of the neurotransmitter:sodium symporter family, is responsible for termination of serotonergic signaling by re-uptake of serotonin (5-HT) into the presynaptic neuron. Its key role in synaptic transmission makes it a major drug target, e.g. for the treatment of depression, an...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-09675-z
更新日期:2019-04-11 00:00:00
abstract::An amendment to this paper has been published and can be accessed via a link at the top of the paper. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-020-17712-5
更新日期:2020-07-27 00:00:00
abstract::YUCCA (YUC) proteins constitute a family of flavin monooxygenases (FMOs), with an important role in auxin (IAA) biosynthesis. Here we report that Arabidopsis plants overexpressing YUC6 display enhanced IAA-related phenotypes and exhibit improved drought stress tolerance, low rate of water loss and controlled ROS accum...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9041
更新日期:2015-08-28 00:00:00
abstract::Human Ebp1 is a member of the proliferation-associated 2G4 (PA2G4) family and plays an important role in cancer regulation. Ebp1 shares the methionine aminopeptidase (MetAP) fold and binds to mature 80S ribosomes for translational control. Here, we present a cryo-EM single particle analysis reconstruction of Ebp1 boun...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-14603-7
更新日期:2020-02-07 00:00:00
abstract::Interactions between metal nanoparticles and support materials can strongly influence the performance of catalysts. In particular, reducible oxidic supports can form suboxides that can decorate metal nanoparticles and enhance catalytic performance or block active sites. Therefore, tuning this metal-support interaction...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-06903-w
更新日期:2018-10-26 00:00:00
abstract::Clostridium difficile is the leading cause of nosocomial diarrhea and colitis in the industrialized world. Disruption of the protective gut microbiota by antibiotics enables colonization by multidrug-resistant C. difficile, which secrete up to three different protein toxins that are responsible for the gastrointestina...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07705-w
更新日期:2018-12-07 00:00:00
abstract::Aortic dissection and intramural haematoma comprise an aortopathy involving separation of the aortic wall. Underlying mechanisms of the condition remain unclear. Here we show that granulocyte macrophage colony-stimulating factor (GM-CSF) is a triggering molecule for this condition. Transcription factor Krüppel-like fa...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7994
更新日期:2015-04-29 00:00:00
abstract::One-fourth of Plasmodium falciparum proteins have asparagine repeats that increase the propensity for aggregation, especially at elevated temperatures that occur routinely in malaria-infected patients. Here we report that a Plasmodium Asn repeat-containing protein (PFI1155w) formed aggregates in mammalian cells at feb...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms2306
更新日期:2012-01-01 00:00:00
abstract::FeV(O)(OH) species have long been proposed to play a key role in a wide range of biomimetic and enzymatic oxidations, including as intermediates in arene dihydroxylation catalyzed by Rieske oxygenases. However, the inability to accumulate these intermediates in solution has thus far prevented their spectroscopic and c...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-08668-2
更新日期:2019-02-22 00:00:00
abstract::Replacing sluggish oxygen evolution reaction (OER) with hydrazine oxidation reaction (HzOR) to produce hydrogen has been considered as a more energy-efficient strategy than water splitting. However, the relatively high cell voltage in two-electrode system and the required external electric power hinder its scalable ap...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-15563-8
更新日期:2020-04-15 00:00:00
abstract::Multi-drug strategies have been attempted to prolong the efficacy of existing antibiotics, but with limited success. Here we show that the evolution of multi-drug-resistant Escherichia coli can be manipulated in vitro by administering pairs of antibiotics and switching between them in ON/OFF manner. Using a multiplexe...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms15589
更新日期:2017-06-08 00:00:00
abstract::Adaptive optics by direct imaging of the wavefront distortions of a laser-induced guide star has long been used in astronomy, and more recently in microscopy to compensate for aberrations in transparent specimens. Here we extend this approach to tissues that strongly scatter visible light by exploiting the reduced sca...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms8276
更新日期:2015-06-15 00:00:00
abstract::During epithelial morphogenesis, cell contacts (junctions) are constantly remodeled by mechanical forces that work against adhesive forces. E-cadherin complexes play a pivotal role in this process by providing persistent cell adhesion and by transmitting mechanical tension. In this context, it is unclear how mechanica...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-07448-8
更新日期:2018-11-27 00:00:00
abstract::A central question in stem cell biology is the relationship between stem cells and their niche. Although previous reports have uncovered how signaling molecules released by niche cells support stem cell function, the role of the extra-cellular matrix (ECM) within the niche is unclear. Here, we show that upon activatio...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-018-03425-3
更新日期:2018-03-14 00:00:00
abstract::Herbivore-induced volatile organic compounds prime non-attacked plant tissues to respond more strongly to subsequent attacks. However, the key volatiles that trigger this primed state remain largely unidentified. In maize, the release of the aromatic compound indole is herbivore-specific and occurs earlier than other ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7273
更新日期:2015-02-16 00:00:00
abstract::The originally published version of this Article contained errors in Figure 4. In panel b, the square and diamond labels associated with the uppermost survival curve were incorrectly displayed as 'n' and 'u', respectively. These errors have now been corrected in both the PDF and HTML versions of the Article. ...
journal_title:Nature communications
pub_type: 杂志文章,已发布勘误
doi:10.1038/s41467-017-02205-9
更新日期:2018-01-10 00:00:00
abstract::Phase transitions in amorphous alloys under pressure are an important fundamental problem. Here we report on a first-principles study that reproduces the recently discovered pressure-induced crystallization of amorphous Ce100-xAlx (x<25) alloys and reveals an atomistic transformation mechanism. Contrary to common beli...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms7493
更新日期:2015-03-09 00:00:00
abstract::The high photon flux and femtosecond pulse duration of hard X-ray free-electron lasers have spurred a large variety of novel and fascinating experiments in physical, chemical and biological sciences. Many of these experiments depend fundamentally on a clean, well-defined wavefront. Here we explore the wavefront proper...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms1950
更新日期:2012-07-10 00:00:00
abstract::Considerable progress in the fabrication of quasicrystals demonstrates that they can be realized in a broad range of materials. However, the development of chemistries enabling direct experimental observation of early quasicrystal growth pathways remains challenging. Here, we report the synthesis of four surfactant-di...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-017-00351-8
更新日期:2017-08-15 00:00:00
abstract::Van Allen radiation belts consist of relativistic electrons trapped by Earth's magnetic field. Trapped electrons often drift azimuthally around Earth and display a butterfly pitch angle distribution of a minimum at 90° further out than geostationary orbit. This is usually attributed to drift shell splitting resulting ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms9590
更新日期:2015-10-05 00:00:00
abstract::Autophagosomes are double-membrane vesicles that sequester cytoplasmic material for lysosomal degradation. Their biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. This process depends on the regulated activation of the Atg1-kinase complex. However, the underlying molecular mechan...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10338
更新日期:2016-01-12 00:00:00
abstract::Most chemical vapor deposition methods for transition metal dichalcogenides use an extremely small amount of precursor to render large single-crystal flakes, which usually causes low coverage of the materials on the substrate. In this study, a self-capping vapor-liquid-solid reaction is proposed to fabricate large-gra...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-020-17517-6
更新日期:2020-07-23 00:00:00
abstract::The insulin/IGF-1 signalling (IIS) pathway plays an important role in the regulation of larval diapause, the long-lived growth arrest state called dauer arrest, in Caenorhabditis elegans. In this nematode, 40 insulin-like peptides (ILPs) have been identified as putative ligands of the IIS pathway; however, it remains ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms10573
更新日期:2016-02-03 00:00:00
abstract::Identification of the optimal quantum metrological protocols in realistic many particle quantum models is in general a challenge that cannot be efficiently addressed by the state-of-the-art numerical and analytical methods. Here we provide a comprehensive framework exploiting matrix product operators (MPO) type tensor...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/s41467-019-13735-9
更新日期:2020-01-14 00:00:00
abstract::The laboratory mouse is the workhorse of immunology, used as a model of mammalian immune function, but how well immune responses of laboratory mice reflect those of free-living animals is unknown. Here we comprehensively characterize serological, cellular and functional immune parameters of wild mice and compare them ...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14811
更新日期:2017-05-03 00:00:00
abstract::Despite a high degree of homology, insulin receptor (IR) and IGF-1 receptor (IGF1R) mediate distinct cellular and physiological functions. Here, we demonstrate how domain differences between IR and IGF1R contribute to the distinct functions of these receptors using chimeric and site-mutated receptors. Receptors with t...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms14892
更新日期:2017-03-27 00:00:00
abstract::The nitrogen-vacancy (NV) centre in diamond is emerging as a promising platform for solid-state quantum information processing and nanoscale metrology. Of interest in these applications is the manipulation of the NV charge, which can be attained by optical excitation. Here, we use two-colour optical microscopy to inve...
journal_title:Nature communications
pub_type: 杂志文章
doi:10.1038/ncomms12660
更新日期:2016-08-30 00:00:00