Abstract:
OBJECTIVES:After surgical or endovascular revascularization, some ischemic lesions will not heal, while some others will heal at a variable period of time from the intervention, indicating a multifactorial interaction between local and systematic "wound healing-promoting" factors. Our objective was to identify predictors of wound healing following revascularization for chronic limb-threatening ischemia (CLTI). METHODS:A literature review was performed to identify published research concerning clinical, biochemical, and noninvasive methods as predictors of wound healing time and wound-free period after surgical and endovascular revascularization for CLTI. RESULTS:Our review indicated that potential predictors included local wound factors, wound depth, patient's comorbidities, medications, smoking and alcohol abuse, poor vessel runoff, and direct versus indirect revascularization. Among the clinical biomarkers, platelet-derived growth factor, transforming growth factor β, basic fibroblast growth factor, tumor necrosis factor α, interleukin (IL) 1, and IL-6 have been proposed as potential predictors. Furthermore, the potential of noninvasive microcirculation assessment to predict proper wound healing has been the topic of extensive investigation. Among the novel methods, transcutaneous measurement of oxygen partial pressure, skin perfusion pressure, oxygen-to-see method, indocyanine green fluorescence imaging, and multispectral optoacoustic tomography have shown promising results. CONCLUSIONS:The risk factor profile of an ischemic lesion in the lower extremities with a delayed/failed healing response, following a successful revascularization, is not fully clarified. Although many predictors have been assessed so far, further research needs to be done to identify the optimal clinical and biochemical indices and the noninvasive technique assessing the microcirculation that is associated with complete wound healing.
journal_name
Vasc Endovascular Surgjournal_title
Vascular and endovascular surgeryauthors
Antonopoulos CN,Lazaris A,Venermo M,Geroulakos Gdoi
10.1177/1538574419868863subject
Has Abstractpub_date
2019-11-01 00:00:00pages
649-657issue
8eissn
1538-5744issn
1938-9116journal_volume
53pub_type
杂志文章,评审abstract::Insufficient renal artery length for renal sympathetic denervation (RDN) is defined as having a main renal artery shorter than 20 mm in length. Such an anatomy is considered a contraindication for most of the currently available endovascular RDN devices. The concern stems from the need to distribute the ablation point...
journal_title:Vascular and endovascular surgery
pub_type: 信件
doi:10.1177/1538574416629564
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abstract::We describe a case of concomitant fibromuscular dysplasia (FMD) and atherosclerotic internal carotid artery (ICA) disease in a symptomatic patient. Sixty-eight-year-old female presented for evaluation of a transient ischemic attack. Imaging revealed severe proximal >80% ICA stenosis with severe FMD to mid and distal I...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574418819299
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abstract::Ovarian vein thrombosis is a rare but serious condition that may cause sepsis in the postpartum patient or may be associated with thrombosis of the inferior vena cava or renal vein. A 30-year-old woman presented 2 weeks postpartum with sudden onset of dyspnea and rightsided pleuritic chest pain. She was diagnosed with...
journal_title:Vascular and endovascular surgery
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doi:10.1177/1538574406291332
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abstract::The objective of this study was to evaluate the clinical and duplex outcome after carotid endarterectomy (CEA) in recently symptomatic patients aged 80 years or older. Information was assembled from a prospective data collection of all CEAs performed from January 1986 to December 1999. Included were all patients with ...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440203600601
更新日期:2002-11-01 00:00:00
abstract:UNLABELLED:Revascularization of patients with intermittent claudication (IC) is recommended only for selected patients who have chronic pain or disabling disease. However, improvement in the quality of life (QoL) could justify more widespread use. OBJECTIVES:To determine the effect of conservative treatment and revasc...
journal_title:Vascular and endovascular surgery
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doi:10.1177/1538574410376602
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abstract::Acute renal artery occlusion is a rare but threatening problem; optimal therapeutic treatment remains a challenge, and ultimate outcomes are still to be defined. In the last decades, several reports or short-case experiences have been reported describing the use of selective infusion of lytic agents into renal artery ...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574408314445
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abstract::We report a case of an abdominal aortic aneurysm (AAA) that underwent inflammatory transformation which we treated medically with corticosteroids. Medical therapy resulted in resolution of presenting symptoms and observed inflammatory changes. We review the clinical features, associated pathology, diagnostic, and ther...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
doi:10.1177/1538574413510616
更新日期:2014-01-01 00:00:00
abstract::We report the clinical details, imaging findings, and management for a 39-year-old female presenting with recurrent episodes of pain in abdomen due to systemic lupus erythematous vasculitis associated with spontaneous isolated inferior mesenteric dissection. Spontaneous mesenteric artery dissection is an uncommon caus...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574418773472
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abstract::Endovascular repair offers minimally invasive management of otherwise complex thoracic aneurysms. Here, a case is reported of a 74-year-old man, a known hypertensive and ex-smoker, who underwent fiberoptic bronchoscopy for gradually progressing intermittent hoarseness of voice, which revealed incomplete left vocal cor...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574407305460
更新日期:2007-12-01 00:00:00
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journal_title:Vascular and endovascular surgery
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doi:10.1177/1538574420941298
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journal_title:Vascular and endovascular surgery
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doi:10.1177/1538574410365731
更新日期:2010-07-01 00:00:00
abstract::The increasing number of patients requiring hemodialysis and the limited number of access sites have resulted in an increase in multiple graft revisions to maintain access for hemodialysis. Venous outflow or anastomotic stenoses in vascular grafts tend to recur and contribute to the difficulty in maintaining a functio...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574406291803
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abstract:OBJECTIVE:The baroreceptor at the carotid body plays an important role in hemodynamic autoregulation. Manipulation of the baroreceptor during carotid endarterectomy (CEA) or radial force from carotid artery angioplasty and/or stenting (CAS) may cause both intraoperative and postoperative hemodynamic instability. The pu...
journal_title:Vascular and endovascular surgery
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doi:10.1177/1538574419828088
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journal_title:Vascular and endovascular surgery
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doi:10.1177/1538574412445600
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abstract::Inadvertent complications of jugular vein catheterization are not uncommon, however, a persistent symptomatic carotid-jugular fistula has been rarely reported. A 72-year-old male with infected surgical wound after coxofemoral disarticulation for sarcoma presented with symptoms of acute right heart failure. A fistula b...
journal_title:Vascular and endovascular surgery
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doi:10.1177/1538574416675675
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abstract::Prosthetic devices that come into contact with blood ultimately fail secondary to thrombus formation. This limits the utility of a variety of materials used to surgically treat cardiovascular disease, including vascular grafts and stents, as well as sensors and catheters placed within the circulatory system. Moreover,...
journal_title:Vascular and endovascular surgery
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journal_title:Vascular and endovascular surgery
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doi:10.1177/153857440503900403
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abstract::Lower extremity vascular injuries following trauma are rare events that require prompt identification and management in order to prevent ischemia and limb loss. Endovascular approaches, rather than traditional open procedures, are increasingly used to treat a wide range of vascular disease. The use of endovascular rep...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
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journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
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journal_title:Vascular and endovascular surgery
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abstract::The aim of this study was to report the results of high-energy endovenous laser treatment to measure the relationship between the fluence and the outcome in terms of recanalization. In 97 patients, 129 great saphenous veins were treated with endovenous laser treatment, using a 980-nm diode laser. Follow-up visits were...
journal_title:Vascular and endovascular surgery
pub_type: 临床试验,杂志文章
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journal_title:Vascular and endovascular surgery
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journal_title:Vascular and endovascular surgery
pub_type: 社论,评审
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journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
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abstract::Patients with end-stage renal disease (ESRD) who present with critical limb ischemia (CLI) have become an increasingly common and complex treatment problem for vascular surgeons. Dialysis patients have high short-term mortality rates regardless of whether revascularization is pursued. ESRD patients with CLI can be man...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
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abstract:BACKGROUND/PURPOSE:This study analyzes the safety and efficacy of carotid angioplasty/stenting (CAS) with embolic protection devices in high surgical risk (HSR) patients. PATIENT POPULATION/METHODS: This study includes 100 consecutive HSR patients, who were followed prospectively, and had carotid duplex ultrasounds at ...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
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journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
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更新日期:2003-03-01 00:00:00
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journal_title:Vascular and endovascular surgery
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更新日期:2018-04-01 00:00:00
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journal_title:Vascular and endovascular surgery
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journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440203600104
更新日期:2002-01-01 00:00:00