Abstract:
:A strain of Staphylococcus aureus (M7) contains a transmissible element determining production of penicillinase, and resistance to cadmium ions, neomycin, streptomycin and kanamycin (CPNS). This element was transferred either in toto or in fragments at low frequency from strain M7. The fragment (NS) possesses features typical of chromosomal genes and the fragment (CP), like (CPNS) itself, exhibits plasmid features. The element (CPNS) is transferred in mixed culture at high frequency, up to 10(-3), between other strains of staphylococci. Lysogenisation of the recipient increases the frequency of transfer. The frequency of transduction of (CPNS), (CP) and (NS) from cell-free lysates corresponds well with the transfer frequency of each of these elements in mixed culture. A possible mechanism for the evolution of (CPNS) is discussed.
journal_name
J Med Microbioljournal_title
Journal of medical microbiologyauthors
Lacey RWdoi
10.1099/00222615-12-3-311subject
Has Abstractpub_date
1979-08-01 00:00:00pages
311-9issue
3eissn
0022-2615issn
1473-5644journal_volume
12pub_type
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