Properties of an unusual genetic element in Staphylococcus aureus.

Abstract:

:A strain of Staphylococcus aureus (M7) contains a transmissible element determining production of penicillinase, and resistance to cadmium ions, neomycin, streptomycin and kanamycin (CPNS). This element was transferred either in toto or in fragments at low frequency from strain M7. The fragment (NS) possesses features typical of chromosomal genes and the fragment (CP), like (CPNS) itself, exhibits plasmid features. The element (CPNS) is transferred in mixed culture at high frequency, up to 10(-3), between other strains of staphylococci. Lysogenisation of the recipient increases the frequency of transfer. The frequency of transduction of (CPNS), (CP) and (NS) from cell-free lysates corresponds well with the transfer frequency of each of these elements in mixed culture. A possible mechanism for the evolution of (CPNS) is discussed.

journal_name

J Med Microbiol

authors

Lacey RW

doi

10.1099/00222615-12-3-311

subject

Has Abstract

pub_date

1979-08-01 00:00:00

pages

311-9

issue

3

eissn

0022-2615

issn

1473-5644

journal_volume

12

pub_type

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