Phage resistance in lactic acid bacteria.

abstract：:An immunological demonstration of alpha-fetoprotein (AFP) in uterine cytosol from immature rats is reported. The identity between serum AFP and the estrogen binding 4.5 S macromolecular complex of uterine cytosol was demonstrated by the use of a specific immunoadsorbent to AFP. Analysis of the sedimentation profile ...

journal_title：Biochimie

authors： Aussel C,Uriel J,Michel G,Baulieu EE

更新日期：1974-01-01 00:00:00

abstract：:Carbonic anhydrases (CAs, EC 4.2.1.1) are metalloenzymes found throughout the phylogenetic tree. The β-class carbonic anhydrases (β-CAs) are the predominating class of CAs in plants. Growing evidence underscores the importance of β-CAs in plant immunity and environmental adaptation in addition to their roles in photos...

journal_title：Biochimie

authors： Wang M,Zhang Q,Liu FC,Xie WF,Wang GD,Wang J,Gao QH,Duan K

更新日期：2014-02-01 00:00:00

abstract：:The structure of the F0 part of ATP synthases from E. coli and Neurospora crassa was analyzed by hydrophobic surface labeling with [125I]TID. In the E. coli F0 all three subunits were freely accessible to the reagent, suggesting that these subunits are independently integrated in the membrane. Labeled amino acid resid...

journal_title：Biochimie

authors： Hoppe J,Sebald W

更新日期：1986-03-01 00:00:00

abstract：:Human immunodeficiency virus (HIV)-infected cells actively release the transcriptional activator (Tat) viral protein that is required for efficient HIV gene transcription. Extracellular Tat is able to enter uninfected cells. We recently reported that internalized Tat escapes endosomes to reach the cytosol and is then ...

journal_title：Biochimie

authors： Beaumelle B,Tóth P,Malak OA,Chopard C,Loussouarn G,Vitale N

更新日期：2017-10-01 00:00:00

abstract：:(-)-Epigallocatechin-3-gallate (EGCG), a well-known chemopreventive factor, induces cancer cells undergoing apoptosis. Over the last several years, we have shown that the mitochondrial NADP(+)-dependent isocitrate dehydrogenase (IDPm) functions as an antioxidant and anti-apoptotic protein by supplying NADPH to antioxi...

journal_title：Biochimie

authors： Kil IS,Jung KH,Nam WS,Park JW

更新日期：2011-10-01 00:00:00

abstract：:Sialidase catalyzes the removal of sialic acids from glycoconjugates. Recently, medaka sialidase Neu1 has been cloned and its enzymatic properties were investigated. Although enzymatic properties of this sialidase, such as optimal pH and substrate specificity, exhibits high similarity with human NEU1, Neu1 physiologic...

journal_title：Biochimie

authors： Ryuzono S,Takase R,Kamada Y,Ikenaga T,Chigwechokha PK,Komatsu M,Shiozaki K

更新日期：2017-04-01 00:00:00

abstract：:The human ribosomal protein SA, known also as a precursor of the cell-surface laminin receptor, LAMR, is a protein of the 40S ribosomal subunit. It is homologous to eubacterial ribosomal protein S2p, but has a eukaryote-specific C-terminal domain (CTD) that is responsible in LAMR for the binding of laminin as well as ...

journal_title：Biochimie

authors： Malygin AA,Babaylova ES,Loktev VB,Karpova GG

更新日期：2011-03-01 00:00:00

abstract：:The oxidation of beta-D-glucose with glucose oxidase generally requires oxygen, which, under normal conditions is present at low concentrations in the reaction medium. Experiments show that glucose oxidase is no longer saturated by oxygen at enzyme concentrations greater than 0.4 mg.ml1. This is due to the decrease in...

journal_title：Biochimie

authors： Boudrant J,Cheftel C

更新日期：1975-01-01 00:00:00

abstract：:Heat shock proteins (Hsps) are involved in several important aspects of the cell proteostasis. Hsp90 interacts with at least a tenth of the cell proteome helping a large number of proteins to fold correctly. Hsp90 function is modulated by several co-chaperones having TPR (tetratricopeptide repeat) domains that allow f...

journal_title：Biochimie

authors： Araujo SA,Martins GH,Quel NG,Aragão AZB,Morea EGO,Borges JC,Houry WA,Cano MIN,Ramos CHI

更新日期：2021-01-06 00:00:00

abstract：:All phytopathogenic fungi have two catalase-peroxidase paralogues located either intracellularly (KatG1) or extracellularly (KatG2). Here, for the first time a secreted bifunctional, homodimeric catalase-peroxidase (KatG2 from the rice blast fungus Magnaporthe grisea) has been produced heterologously with almost 100% ...

journal_title：Biochimie

authors： Zámocký M,Droghetti E,Bellei M,Gasselhuber B,Pabst M,Furtmüller PG,Battistuzzi G,Smulevich G,Obinger C

更新日期：2012-03-01 00:00:00

abstract：:So far, no efficient affinity chromatography for CCK receptor purification has been reported that prevented obtention of sequenceable amounts of purified receptor. In this work, 10% of plasma membrane receptor sites were specifically cross-linked with the photoreactive cleavable agonist 125I-ASD-[Thr28, Ahx31]-CCK-25-...

journal_title：Biochimie

authors： Dufresne M,Poirot S,Jimenez J,Vaysse N,Fourmy D

更新日期：1992-02-01 00:00:00

abstract：:In septic shock patients, alterations of plasma phospholipid fatty acid profile have never been described. The purpose of this monocentric, non-interventional, observational prospective study was to describe this fatty acid profile in the early phase of septic shock in intensive care unit. Thirty-seven adult patients ...

journal_title：Biochimie

authors： Rival T,Cinq-Frais C,Silva-Sifontes S,Garcia J,Riu B,Salvayre R,Genestal M,Caspar-Bauguil S

更新日期：2013-11-01 00:00:00

abstract：:Since the initial identification of leptin as the product of the ob gene in 1994, the signaling pathways by which this hormone alters cell physiology have been the subject of extensive investigations. The fact that leptin can induce nitric oxide (NO) production was first demonstrated in studies of the pituitary gland ...

journal_title：Biochimie

authors： Joffin N,Niang F,Forest C,Jaubert AM

更新日期：2012-10-01 00:00:00

abstract：:Sticholysin II (StII) is a pore-forming toxin of biomedical interest that belongs to the actinoporin protein family. Sticholysins are currently under examination as an active immunomodulating component of a vaccinal platform against tumoral cells and as a key element of a nucleic acids delivery system to cell cytosol....

journal_title：Biochimie

authors： Soto C,Bergado G,Blanco R,Griñán T,Rodríguez H,Ros U,Pazos F,Lanio ME,Hernández AM,Álvarez C

更新日期：2018-05-01 00:00:00

abstract：:Lipolytic activities of Yarrowia lipolytica LIP2 lipase (YLLIP2), human pancreatic (HPL) and dog gastric (DGL) lipases were first compared using lecithin-stabilized triacylglycerol (TAG) emulsions (Intralipid) at various pH and bile salt concentrations. Like DGL, YLLIP2 was able to hydrolyze TAG droplets covered by a ...

journal_title：Biochimie

authors： Bénarouche A,Point V,Carrière F,Cavalier JF

更新日期：2014-07-01 00:00:00

abstract：:Plant serine proteases have been widely used in food science and technology as well as in medicine. In this sense, several plant serine proteases have been proposed as potential anti-coagulants and anti-platelet agents. Previously, we have reported the purification and identification of a plant serine protease from So...

journal_title：Biochimie

authors： Pepe A,Frey ME,Muñoz F,Fernández MB,Pedraza A,Galbán G,García DN,Daleo GR,Guevara MG

更新日期：2016-06-01 00:00:00

abstract：:A major tolerance mechanism that functions to replicate damaged genomic DNA across lesions that have escaped elimination by repair mechanism is translesion DNA synthesis (TLS). DNA polymerase kappa (Pol kappa), a specialised low-fidelity DNA polymerase which is able to perform DNA synthesis across several damaged base...

journal_title：Biochimie

authors： Bavoux C,Hoffmann JS,Cazaux C

更新日期：2005-07-01 00:00:00

abstract：:Plasmalogens (Pls) represent a specific subclass of glycerophospholipids characterized by the presence of a vinyl-ether bond at the sn-1 position of glycerol. Pls are quantitatively important in membranes of neuronal tissues, including the brain and the retina, where they can represent until almost two-third of ethano...

journal_title：Biochimie

authors： Saab S,Mazzocco J,Creuzot-Garcher CP,Bron AM,Bretillon L,Acar N

更新日期：2014-12-01 00:00:00

abstract：:Triple-negative breast cancer (TNBC) is a heterogeneous group of breast cancer with one common feature: distinctly metastatic nature with higher rate of relapse and shorter survival compared with other subtypes of breast cancer. The epithelial to mesenchymal transition (EMT) is highly associated with cancer metastasis...

journal_title：Biochimie

authors： Liang L,Liu X,He J,Shao Y,Liu J,Wang Z,Xia L,Han T,Wu P

更新日期：2019-07-01 00:00:00

abstract：:Because of the ability of photosensitizers to induce specific photochemical reactions in vivo, leading to cell injury and death, many such molecules have been considered as therapeutic agents. Among them two classes of sensitizers, i.e. furocoumarins (psoralens) and porphyrins, are currently used for the photochemothe...

journal_title：Biochimie

authors： Moreno G

更新日期：1986-06-01 00:00:00

abstract：:Kinetic parameters characterizing the catalytic activities of enzymes are typically investigated in dilute solutions. However, in reality, these reactions occur in cells that, in addition to water and ions, are full of other macromolecules including proteins, nucleic acids, lipids, and metabolites. Such a crowded envi...

journal_title：Biochimie

authors： Popielec A,Ostrowska N,Wojciechowska M,Feig M,Trylska J

更新日期：2020-09-01 00:00:00

abstract：:The structural difference of flavonoids strongly affects the binding process with plasma proteins. This work in here mainly concerns about the molecular property-binding affinity relationship of dietary flavonoids for common rat plasma proteins (CRPP). The magnitudes of binding constants between flavonoids and CRPP we...

journal_title：Biochimie

authors： Xiao J,Cao H,Chen T,Yang F,Liu C,Xu X

更新日期：2011-02-01 00:00:00

abstract：:Labeling of 21-kDa material was observed when bovine brain soluble fraction was incubated with [adenylate-32P]NAD+ in the presence of GTP. The 21-kDa substrate, slightly smaller than C3 substrate in size, was labeled even without C3 exoenzyme. GTP could be replaced by nucleoside triphosphates other than ATP while ATP ...

journal_title：Biochimie

authors： Badruzzaman M,Miyaoka T,Terashima M,Yamada K,Ohno T,Yamamori C,Tsuchiya M,Shimoyama M

更新日期：1997-07-01 00:00:00

abstract：:Protein-induced DNA bridging and looping is a common mechanism for various and essential processes in bacterial chromosomes. This mechanism is preserved despite the very different bacterial conditions and their expected influence on the thermodynamic and kinetic characteristics of the bridge formation and stability. O...

journal_title：Biochimie

authors： Tardin C

更新日期：2017-11-01 00:00:00

abstract：:The expression of serotonin (5-HT) in the retina was first reported in the sixties. The detection of vesicular monoamine transporter and serotonin receptors in several retinal cells confirm that 5-HT is playing a neuromodulatory role in this structure. Whereas signaling pathways activated by 5-HT receptor binding has ...

journal_title：Biochimie

authors： Masson J

更新日期：2019-06-01 00:00:00

abstract：:We have synthesized and examined a number of fully and partly self-complementary palindromic oligodeoxynucleotides for their ability to assume in solution a unimolecular hairpin structure. The main results obtained by a combined optical and electrophoresis investigation show that: (i) DNA folding needs not be driven b...

journal_title：Biochimie

authors： Xodo LE,Manzini G,Quadrifoglio F,van der Marel G,van Boom JH

更新日期：1989-07-01 00:00:00

abstract：:Innate immune system is the first line of host defense against invading microorganisms. It relies on a limited number of germline-encoded pattern recognition receptors that recognize conserved molecular structures of microbes, referred to as pathogen-/microbe-associated molecular patterns (PAMPs/MAMPs). Bacterial cell...

journal_title：Biochimie

authors： Ray A,Cot M,Puzo G,Gilleron M,Nigou J

更新日期：2013-01-01 00:00:00

abstract：:In man the brain represents about 2% of the body weight, but contains 25% of the body's cholesterol. Cholesterol itself does not cross the blood-brain barrier and is synthesised in situ. Excess cholesterol from brain is exported in the form of oxysterols, or metabolised to steroids, which in contrast to cholesterol ca...

journal_title：Biochimie

authors： Wang Y,Karu K,Griffiths WJ

更新日期：2007-02-01 00:00:00

abstract：:Recent work has shown that a DBF4 analog in yeast may be a target of nitrogen-containing bisphosphonates. DBF4 is an essential protein kinase required for DNA replication from primary eukaryotes to humans and appears to play a critical role in the S-phase checkpoint. It is also required for cell migration and cell sur...

journal_title：Biochimie

authors： Mansouri M,Mirzaei SA,Lage H,Mousavi SS,Elahian F

更新日期：2014-04-01 00:00:00

abstract：:Skin aging is characterized by different features including wrinkling, atrophy of the dermis and loss of elasticity associated with damage to the extracellular matrix protein elastin. The aim of this study was to investigate the aging process of skin elastin at the molecular level by evaluating the influence of intrin...

journal_title：Biochimie

authors： Mora Huertas AC,Schmelzer CE,Hoehenwarter W,Heyroth F,Heinz A

更新日期：2016-09-01 00:00:00