Abstract:
:Objective: The study investigates how IVC and ET affect hypertensive phenotype in ISIAH rats. Methods: ISIAH rats born as the result of ET and IVC were compared with naturally conceived controls. Results: Embryo transfer from hypertensive ISIAH rats to normotensive recipient dams caused lower SBP and DBP in the female offspring. When ET was accompanied with in vitro culture in R1ECM, not only the female offspring, but also males demonstrated alleviation of hypertension. Conclusions: IVC at the preimplantation embryo stage affected the manifestation of hypertension in the adult ISIAH offspring.
journal_name
Hypertens Pregnancyjournal_title
Hypertension in pregnancyauthors
Igonina TN,Ragaeva DS,Petrova OM,Rozkova IN,Brusentsev EY,Amstislavsky SYdoi
10.1080/10641955.2019.1647232subject
Has Abstractpub_date
2019-11-01 00:00:00pages
208-216issue
4eissn
1064-1955issn
1525-6065journal_volume
38pub_type
杂志文章abstract:OBJECTIVE:The aim of this study was to evaluate maternal and fetal outcome of the subsequent pregnancy of primiparous women with a history of early-onset intrauterine growth restriction (IUGR), prompting delivery before 34 weeks of gestation, without concomitant maternal hypertensive disease. DESIGN:Retrospective coho...
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更新日期:2011-01-01 00:00:00
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journal_title:Hypertension in pregnancy
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journal_title:Hypertension in pregnancy
pub_type: 杂志文章
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journal_title:Hypertension in pregnancy
pub_type: 杂志文章
doi:10.1080/10641950802233064
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journal_title:Hypertension in pregnancy
pub_type: 杂志文章
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journal_title:Hypertension in pregnancy
pub_type: 杂志文章
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journal_title:Hypertension in pregnancy
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pub_type: 杂志文章
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journal_title:Hypertension in pregnancy
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pub_type: 杂志文章,评审
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journal_title:Hypertension in pregnancy
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journal_title:Hypertension in pregnancy
pub_type: 杂志文章,随机对照试验
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更新日期:2018-05-01 00:00:00
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更新日期:2002-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2005-01-01 00:00:00
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journal_title:Hypertension in pregnancy
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pub_type: 杂志文章
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doi:10.1080/10641950600912976
更新日期:2006-01-01 00:00:00