Abstract：
:Transcutaneous electrical nerve stimulation (TNS) was used on 20 patients with severe wrist pain due to rheumatoid arthritis. Three different stimulation frequencies were used: high 70 Hz stimulation (70 TNS), low frequency 3 Hz stimulation (3 TNS) and brief trains of stimuli with an internal frequency of 70 Hz and with a repetition rate of 3 Hz (3-70 TNS). The analgesic effect was evaluated on the patient's own estimate of pain relief and by means of a loading test in which the length of time the patient could hold a weight before and after TNS was used. The loading test and the patients' own estimate of pain relief corresponded well. After 70 TNS, 18 patients could double their loading time. The corresponding figure for 3-70 TNS was 16 patients and for 3 TNS 5 patients. The average duration of pain relief after cessation of stimulation was 18 h for 70 TNS and 15 h for 3-70 TNS, while those who responded to 3 TNS experienced pain relief for only 4 h on average.
journal_name
Painjournal_title
Painauthors
Mannheimer C,Carlsson CAdoi
10.1016/0304-3959(79)90051-4subject
Has Abstractpub_date
1979-06-01 00:00:00pages
329-334issue
3eissn
0304-3959issn
1872-6623pii
00006396-197906000-00006journal_volume
6pub_type
杂志文章相关文献
PAIN文献大全abstract：:Although pediatric functional abdominal pain (FAP) has been linked to abdominal pain later in life, childhood predictors of long-term outcomes have not been identified. This study evaluated whether distinct FAP profiles based on patterns of pain and adaptation in childhood could be identified and whether these profile...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2012.03.026
更新日期：2012-09-01 00:00:00
abstract：:There is evidence of greater opioid prescription to individuals in the United States with mental health conditions. Whether these associations generalize beyond the US prescription environment and to familial mental health and socioeconomic status (SES) has not been examined comprehensively. This study estimated assoc...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001643
更新日期：2019-11-01 00:00:00
abstract：:A psychophysical investigation was carried out to examine whether heat hyperalgesia exists within the secondary mechanical hyperalgesia zone surrounding a capsaicin injection site on hairy skin. A non-contact laser stimulator was used to deliver temperature controlled stimuli to sites within and outside the zone of me...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/s0304-3959(96)03199-5
更新日期：1996-12-01 00:00:00
abstract：:Bipolar intrapulpal stimulation was applied to human teeth using the same procedure as in animal experiments. The effects of variation of stimulus parameters on the quality of sensation were studied. A prepain sensation exists which cannot be explained by diffusion of the stimulus to periodontal tissues. When the inte...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(77)90128-2
更新日期：1977-12-01 00:00:00
abstract：:In this study, we examined the relationship between astrocyte activation in the cuneate nucleus (CN) and behavioral hypersensitivity after chronic constriction injury (CCI) of the median nerve. In addition, we also examined the effects of pre-emptive treatment with a number of drugs on astrocyte activation and hyperse...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2009.11.004
更新日期：2010-01-01 00:00:00
abstract：:In the skin surrounding a site of injury, hyperalgesia develops to mechanical stimuli. Two types of secondary hyperalgesia (to light touch and punctate stimuli) have recently been differentiated, based on different durations and sizes of the area involved. We studied secondary hyperalgesia in a subject who had a loss ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(93)90077-3
更新日期：1993-05-01 00:00:00
abstract：:Chronic pain is currently considered a public health problem with high costs to the individual and society. To improve prevention and treatment of chronic pain, epidemiologic studies are mandatory for assessing chronic pain. The aims of this study were to estimate the prevalence of chronic pain in the adult Danish pop...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2012.07.023
更新日期：2012-12-01 00:00:00
abstract：:The aim of the present study was to investigate changes in the plasma calcitonin gene-related peptide (CGRP) concentration and platelet serotonin (5-hydroxytriptamine, 5-HT) content during the immediate headache and the delayed genuine migraine attack provoked by nitroglycerin. Fifteen female migraineurs (without aura...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2003.09.008
更新日期：2003-12-01 00:00:00
abstract：:Chronic and acute pre-mastectomy pain as well as prevalence and characteristics of phantom phenomena following mastectomy were investigated by interview in a sample of 39 women who had undergone unilateral breast amputation. Twenty of 39 participants reported phantom sensations in the breast. Nine of the participants ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2003.10.007
更新日期：2004-01-01 00:00:00
abstract：:Few surveys have been performed to define the characteristics and impact of breakthrough pain in the cancer population. In this cross-sectional survey of inpatients with cancer, patients responded to a structured interview (the Breakthrough Pain Questionnaire) designed to characterize breakthrough pain, and also compl...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(99)00006-8
更新日期：1999-05-01 00:00:00
abstract：:To investigate the pathways of noxious information in the spinal cord in humans, we recorded cortical potentials following the stimulation of A-delta fibers using a YAG laser applied to two cutaneous points on the back at the C7 and Th10 level, 4cm to the right of the vertebral spinous process. A multiple source analy...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2006.03.009
更新日期：2006-08-01 00:00:00
abstract：:Cognitive factors are thought to play an important mediational role between pain and consequent levels of suffering, yet there has been little investigation of these issues in older chronic pain patients. The present study sought to examine the reliability and validity of the Pain Locus of Control (PLOC) scale when us...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/S0304-3959(99)00284-5
更新日期：2000-04-01 00:00:00
abstract：:Cognitions and beliefs appear important in predicting adjustment to chronic pain. The current study examines how cognitions and beliefs are related to psychosocial functioning. One hundred and sixty-three chronic pain out-patients were assessed. Regression analyses were performed using scores on the Pain Beliefs and P...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(99)00226-2
更新日期：2000-02-01 00:00:00
abstract：:Two models of the relationship between paraspinal EMG and low back pain have been proposed. Specific predictions arising from these are listed and the literature relating to them reviewed. Recent research on patterns of EMG rather than absolute levels is also discussed. It is concluded that there is no consistent evid...
journal_title：Pain
pub_type： 杂志文章,评审
doi：10.1016/0304-3959(84)90093-9
更新日期：1984-10-01 00:00:00
abstract：:Ziconotide is a nonopioid intrathecal analgesic drug used to manage moderate to severe chronic pain. The aim of this work is to assess the safety and efficacy of intrathecal (IT) combination of ziconotide and morphine in malignant pain refractory to high doses of oral opioids. Patients with malignant pain refractory t...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2011.10.002
更新日期：2012-01-01 00:00:00
abstract：:Peripheral nerve injury produces a persistent neuropathic pain state characterized by spontaneous pain, allodynia and hyperalgesia. In this study, we evaluated the possible involvement of A 2ARs in the development of neuropathic pain and the expression of microglia and astrocytes in the spinal cord after sciatic nerve...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2008.07.012
更新日期：2008-11-15 00:00:00
abstract：:Chemical cauterization of the central cornea with silver nitrate was assessed as a superficial injury model of tissue sensitization accompanying acute inflammation. Adult male Sprague-Dawley rats were anesthetized with halothane gas, and the centers of their right corneas treated with a silver nitrate applicator stick...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(03)00295-1
更新日期：2003-10-01 00:00:00
abstract：:This study reports a 9-18 month follow-up of a randomised controlled trial of pain management programmes for chronic, non-malignant pain. Twenty-two inpatients, 18 outpatients and 12 control subjects completed the follow-up assessments. Significant treatment effects were demonstrated by the inpatient group on pain rat...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0304-3959(92)90110-W
更新日期：1992-07-01 00:00:00
abstract：:Injection of high-dose of morphine into the spinal lumbar intrathecal (i.t.) space of rats elicits a nociceptive behavioural syndrome characterized by periodic bouts of spontaneous agitation and severe vocalization. The induced behavioural response such as vocalization and agitation was observed dose-dependently by i....
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(03)00296-3
更新日期：2003-12-01 00:00:00
abstract：:Pain and thermal sensitivity thresholds in healthy volunteers were examined for diurnal variations. The subjects were 11 men aged between 22 and 27 years (means = 23.5, S.D. = 1.5). Data were collected for 2 days, with 7 measurements per day. To ensure the pain specificity of the results the subliminal modality, i.e.,...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(89)90120-6
更新日期：1989-01-01 00:00:00
abstract：:Training in relaxation is a prominent component in multi-disciplinary approaches to the management of chronic pain, although its specific potency in modulating pain has not yet been established. Using a within-session design, the specific effects of relaxation induction were evaluated in a group of benign chronic pain...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(88)90065-6
更新日期：1988-02-01 00:00:00
abstract：:Neuroimaging studies of patients with chronic pain have shown that neurotransmitter abnormalities, including increases in glutamate and decreases in GABA, could be responsible for the cortical hyperactivity and hyperalgesia/allodynia observed in some pain conditions. These finding are particularly evident in the insul...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000000615
更新日期：2016-10-01 00:00:00
abstract：:The purpose of this study was to describe and quantify changes in the movement and EMG patterns caused by tonic noxious pressure on the periosteum of the zygoma during electrically induced rhythmic jaw movements in the decerebrate rabbit. Eight New Zealand rabbits were anesthetized with urethane. EMG electrodes were p...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(95)00028-Q
更新日期：1995-11-01 00:00:00
abstract：:Biopsychosocial models of chronic pain that recognize psychological and environmental factors as important aspects of adjustment to pain have been proposed for understanding chronic pain and related suffering in persons with multiple sclerosis (MS), but such models have not been empirically tested. The objective of th...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2006.07.017
更新日期：2007-01-01 00:00:00
abstract：:Although it is well known that cannabinoids produce antinociception in acute pain models, there is less information on the ability of cannabinoids to alleviate hyperalgesia. In the present study, we determined whether cannabinoids attenuated the development of hyperalgesia produced by intraplantar injection of capsaic...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(98)00263-2
更新日期：1999-05-01 00:00:00
abstract：:The opiate antagonist naloxone has been reported to cause pain relief. Therefore, the effect was determined of naloxone, injected intravenously, on the activity in single neurones of the dorsomedial part of the ventral nucleus (VDM) in the thalamus of rats under urethane anaesthesia elicited by electrical stimulation ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(88)90144-3
更新日期：1988-12-01 00:00:00
abstract：:Tricyclic antidepressants (TCAs) have been found to be useful in the management of a variety of chronic pain conditions, although there is little published regarding the potential efficacy of this class of drug as an adjunct for the control of acute postoperative pain and related symptoms. Twenty-eight patients underg...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0304-3959(93)90166-M
更新日期：1993-03-01 00:00:00
abstract：:Venlafaxine hydrochloride (Effexor) is a structurally novel antidepressant that inhibits reuptake of 5-hydroxytryptamine and noradrenaline, but unlike the older antidepressants, has few side-effects. The objective of this study was to determine whether venlafaxine relieves thermal hyperalgesia in rats with neuropathic...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(96)03223-X
更新日期：1996-11-01 00:00:00
abstract：:This study determined whether opiates alter vascular components of inflammation (hyperthermia, edema and plasma extravasation) in addition to the suppression of hyperalgesia. Rats were administered carrageenan into one hind paw and saline into the other hind paw, followed by i.p. injection of morphine (0.2-5.0 mg/kg) ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(90)90054-H
更新日期：1990-10-01 00:00:00
abstract：:Acute microinjection of mu-, delta-, or kappa-opioid receptor (MOPr, DOPr, KOPr) agonists into the rostral ventromedial medulla (RVM) produces antinociception. Thermal antinociception produced by MOPr and DOPr agonists is potentiated during inflammation [Hurley RW, Hammond DL. The analgesic effects of supraspinal mu a...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2007.07.010
更新日期：2008-06-01 00:00:00
