Future research demands of the United European Gastroenterology (UEG) and its member societies.

abstract：Background:The diagnostic yield of coeliac disease could be improved by screening in at-risk groups, but long-term benefits of this approach are obscure. Objective:To investigate health, quality of life and dietary adherence in adult coeliac patients diagnosed in childhood by screening. Methods:After thorough evaluat...

journal_title：United European gastroenterology journal

authors： Kivelä L,Popp A,Arvola T,Huhtala H,Kaukinen K,Kurppa K

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Biologically naïve patients with inflammatory bowel disease treated with vedolizumab (VDZ) are largely underrepresented in real-world cohorts. A multi-centre, observational cohort study was performed on the effectiveness and safety of VDZ in biologically naïve subjects with Crohn's disease (CD) and ulcerativ...

journal_title：United European gastroenterology journal

authors： Macaluso FS,Fries W,Renna S,Viola A,Muscianisi M,Cappello M,Guida L,Siringo S,Camilleri S,Garufi S,Privitera AC,Belluardo N,Giangreco E,Bertolami C,Vassallo R,Rizzuto G,Orlando R,Ventimiglia M,Orlando A,Sicilian Net

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Acute upper abdominal pain is a frequent symptom leading to hospital admission. OBJECTIVE:To determine whether a primary intra- and extraluminal diagnostic approach enabled by endoscopic ultrasound is as effective as a conventional diagnostic algorithm of transabdominal ultrasound followed by oesophagogastr...

journal_title：United European gastroenterology journal

authors： Jung A,Schlag C,Becker V,von Delius S,Lersch C,Jeliazkova P,Herner A,Bajbouj M,Schuster T,Meining A

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Inflammatory conditions affecting the gut may cause motility disturbances, and ulcerative colitis - one of the main disorders among the inflammatory bowel diseases - may display abnormal colonic motility. AIM:To review the abnormalities of the large bowel in ulcerative colitis, by considering the motility, ...

journal_title：United European gastroenterology journal

authors： Bassotti G,Antonelli E,Villanacci V,Baldoni M,Dore MP

更新日期：2014-12-01 00:00:00

abstract：:Fistulas and fibrosis or strictures represent frequent complications in irritable bowel disease (IBD) patients. To date, treatment options for fistulas are limited and surgery is often required. Similarly, no preventive treatment for fibrosis and stricture formation has been established. Frequently, stricture formatio...

journal_title：United European gastroenterology journal

authors： Scharl M,Bruckner RS,Rogler G

更新日期：2016-08-01 00:00:00

abstract：:One of the aims of the Young Talent Group (YTG) is to make United European Gastroenterology (UEG) more attractive for young fellows interested in gastroenterology, and to involve them actively in UEG activities, by collaborating with young GI sections (YGIS) across Europe. Therefore, the YTG launched a survey to colle...

journal_title：United European gastroenterology journal

authors： Ianiro G,Castro V,Dolak W,Ilie M,Holleran G,Salaga M,van Herwaarden Y,Burisch J,UEG Young Talent Group.

更新日期：2017-08-01 00:00:00

abstract：Background and objective:Psychological states may interfere with visceral sensitivity. Here we investigate associations between psychosocial factors and visceral sensitivity in irritable bowel syndrome (IBS). Methods:Two IBS patient cohorts (Cohort 1: n = 231, Rome II; Cohort 2: n = 141, Rome III) underwent rectal bar...

journal_title：United European gastroenterology journal

authors： Grinsvall C,Törnblom H,Tack J,Van Oudenhove L,Simrén M

更新日期：2018-03-01 00:00:00

abstract：Background:Hepatic encephalopathy is associated with altered gut microbiota. Proton pump inhibitors increase the risk of small bowel bacterial overgrowth. Objectives:This was a case-control study aimed at exploring the relationship of proton pump inhibitor use with the risk of hepatic encephalopathy during hospitaliza...

journal_title：United European gastroenterology journal

authors： Zhu J,Qi X,Yu H,Yoshida EM,Mendez-Sanchez N,Zhang X,Wang R,Deng H,Li J,Han D,Guo X

更新日期：2018-10-01 00:00:00

abstract：Introduction:Fecal microbiota transfer (FMT) is highly effective in the treatment and prevention of recurrent Clostridioides difficile infection (rCDI) with cure rates of about 80% after a single treatment. Nevertheless, the reasons for failure in the remaining 20% remain largely elusive. The aim of the present study w...

journal_title：United European gastroenterology journal

authors： Peri R,Aguilar RC,Tüffers K,Erhardt A,Link A,Ehlermann P,Angeli W,Frank T,Storr M,Glück T,Sturm A,Rosien U,Tacke F,Bachmann O,Solbach P,Stallmach A,Goeser F,Vehreschild MJ,German Clinical Microbiome Study Group (GCMSG

更新日期：2019-06-01 00:00:00

abstract：:Ineffective esophageal motility (IEM) is the most frequently encountered esophageal motility disorder. Patients may present with a variety of symptoms, such as dysphagia, heartburn, odynophagia, and regurgitation. Over the past years, the landscape of esophageal motility testing has been revolutionized; however, our c...

journal_title：United European gastroenterology journal

authors： Scheerens C,Tack J,Rommel N

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Patients with primary oesophageal squamous cell carcinoma are at risk of developing multiple primary tumours in the upper aero digestive tract. To date, most studies are performed in the Asian population. We aimed to evaluate the risk of multiple primary tumours in the upper aero digestive tract and stomach ...

journal_title：United European gastroenterology journal

authors： van de Ven SE,Falger JM,Verhoeven RH,Baatenburg de Jong RJ,Spaander MC,Bruno MJ,Koch AD

更新日期：2020-12-03 00:00:00

abstract：Background:Intestinal microbiota and their metabolites (e.g. short-chain fatty acids (SCFAs)) may influence nonalcoholic fatty liver disease (NAFLD). Objective:The objective of this article is to analyze gut bacterial diversity together with fecal SCFA concentrations and immunophenotyping of peripheral blood in histol...

journal_title：United European gastroenterology journal

authors： Rau M,Rehman A,Dittrich M,Groen AK,Hermanns HM,Seyfried F,Beyersdorf N,Dandekar T,Rosenstiel P,Geier A

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND AND AIM:The efficacy of clipping for preventing delayed bleeding after colorectal endoscopic resection is still controversial. To assess the efficacy of prophylactic clipping, we conducted a meta-analysis of randomized controlled trials. METHODS:We searched PubMed, the Cochrane library, and the Igaku-chuo-z...

journal_title：United European gastroenterology journal

authors： Nishizawa T,Suzuki H,Goto O,Ogata H,Kanai T,Yahagi N

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Prucalopride is a selective, high-affinity, 5-hydroxytryptamine (serotonin) type 4 (5-HT4) receptor agonist with gastrointestinal prokinetic activities. This integrated analysis of data from three double-blind phase III trials (ClinicalTrials.gov: NCT00488137, NCT00483886, NCT00485940) compared the efficacy ...

journal_title：United European gastroenterology journal

authors： Tack J,Quigley E,Camilleri M,Vandeplassche L,Kerstens R

更新日期：2013-02-01 00:00:00

abstract：Background:Barrett's esophagus (BE) is rare in African Americans (AA). However, the risk difference magnitude in histologic BE prevalence between AA and non-Hispanic whites (nHw) has not been quantified to date. Objective:The objective of this article is to determine the degree of histologic BE risk difference between...

journal_title：United European gastroenterology journal

authors： Alkaddour A,Palacio C,Vega KJ

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Peroral endoscopic esophageal myotomy (POEM) represents a less invasive alternative, as compared with conventional laparoscopic Heller myotomy for treating achalasia patients. In the last years, a number of prospective and retrospective experiences with POEM use for achalasia have been published. METHODS:Re...

journal_title：United European gastroenterology journal

authors： Barbieri LA,Hassan C,Rosati R,Romario UF,Correale L,Repici A

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Symptomatically 'silent' gastro-oesophageal reflux disease (GORD) may be underdiagnosed. OBJECTIVE:To determine the prevalence of untreated GORD without heartburn and/or regurgitation in primary care. METHODS:Patients were included if they had frequent upper gastrointestinal symptoms and had not taken a pr...

journal_title：United European gastroenterology journal

authors： Vakil N,Wernersson B,Ohlsson L,Dent J

更新日期：2014-06-01 00:00:00

abstract：:Barrett's oesophagus is a pre-malignant condition associated with the development of oesophageal adenocarcinoma. Currently white light endoscopy and biopsy is the mainstay diagnostic tool. Yet this approach is troubled by issues related to cumbersome biopsy sampling, biopsy sampling errors and cost. Therefore in order...

journal_title：United European gastroenterology journal

authors： Sharma N,Srivastava S,Kern F,Xian W,Ming T,McKeon F,Ho KY

更新日期：2016-12-01 00:00:00

abstract：Background:Sporadic nonampullary duodenal adenocarcinoma is a rare malignant neoplasm in which poor prognosis is often associated with delayed diagnosis. Objective:A case-control study was designed to evaluate the clinical and endoscopic characteristics of patients with nonampullary duodenal epithelial tumours (NADETs...

journal_title：United European gastroenterology journal

authors： Matsuzaki J,Suzuki H,Shimoda M,Mori H,Fukuhara S,Miyoshi S,Masaoka T,Iwao Y,Kanai Y,Kanai T

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The 2016, United European Gastroenterology evidence-based guidelines for the diagnosis and therapy of chronic pancreatitis (HaPanEU) provided evidence-based recommendations for the management of chronic pancreatitis and allowed for the objective evaluation of the quality of care in several doma...

journal_title：United European gastroenterology journal

authors： de Rijk FE,Kempeneers MA,Bruno MJ,Besselink MG,van Goor H,Boermeester MA,van Geenen EJ,van Hooft JE,van Santvoort HC,Verdonk RC,Dutch Pancreatitis Study Group.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Primary bile acid diarrhoea (BAD) is associated with increased bile acid synthesis and low fibroblast growth factor 19 (FGF19). Bile acid sequestrants are used as therapy, but are poorly tolerated and may exacerbate FGF19 deficiency. AIM:The purpose of this study was to evaluate the pharmacological effects ...

journal_title：United European gastroenterology journal

authors： Appleby RN,Bajor A,Gillberg PG,Graffner H,Simrén M,Ung KA,Walters J

更新日期：2017-04-01 00:00:00

abstract：Background:Cortiment®MMX® (budesonide MMX®) is currently approved for the induction of remission in mild-to-moderate ulcerative colitis (UC) patients when 5-ASA treatment is not sufficient. Data in real-life settings are lacking. Methods:This was a multicentre observational prospective cohort study conducted in Europe...

journal_title：United European gastroenterology journal

authors： Danese S,Hart A,Dignass A,Fiorino G,Louis E,Bonovas S,D'Haens G,Dotan I,Rogler G,Paridaens K,Peyrin-Biroulet L

更新日期：2019-11-01 00:00:00

abstract：Introduction:Endoscopic mucosal resection and endoscopic submucosal dissection are demanding procedures. This study aims to establish face, content and expert validity of the live porcine model in performing endoscopic mucosal resection, endoscopic submucosal dissection, complication management and to assess it as a tr...

journal_title：United European gastroenterology journal

authors： Küttner-Magalhães R,Dinis-Ribeiro M,Bruno MJ,Marcos-Pinto R,Rolanda C,Koch AD

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Sphingosine kinase 1 (SphK1)/sphingosine-1-phosphate (S1P)/sphingosine-1-phosphate receptors (S1PRs) signaling plays a key role in inflammatory responses. Lei et al. showed that SphK1 inhibition presented a hepatoprotective effect on acute liver damage via decreasing hepatic high-mobility group box 1 (HMGB1)...

journal_title：United European gastroenterology journal

authors： Tian T,Tian W,Yang F,Zhao R,Huang Q,Zhao Y

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:The risk of esophageal adenocarcinoma (EAC) in non-dysplastic Barrett's esophagus (NDBE) is considered to be approximately 0.3% per year or even lower, according to population-based studies. Data from countries with low EAC incidence are scarce. Our principal aim was to determine the incidence of high-grade ...

journal_title：United European gastroenterology journal

authors： Pereira AD,Chaves P

更新日期：2016-06-01 00:00:00

abstract：Background:Modulating gut microbiota is a potential treatment for irritable bowel syndrome (IBS). This meta-analysis explored whether fecal microbiota transplantation (FMT) is successful in treating IBS. Methods:A systematic review was performed to find trials on FMT in IBS. Ratios and relative ratios (RR) of improvem...

journal_title：United European gastroenterology journal

authors： Myneedu K,Deoker A,Schmulson MJ,Bashashati M

更新日期：2019-10-01 00:00:00

abstract：Background:Very few data regarding the use of infliximab in children with very early-onset inflammatory bowel disease (VEO-IBD) have been reported. Objective:We aimed to assess the efficacy and the safety of infliximab in children with VEO-IBD compared with older children. Methods:Children treated with infliximab wer...

journal_title：United European gastroenterology journal

authors： Bramuzzo M,Arrigo S,Romano C,Filardi MC,Lionetti P,Agrusti A,Dipasquale V,Paci M,Zuin G,Aloi M,Strisciuglio C,Miele E,Pastore M,Martelossi S,Alvisi P,SIGENP IBD Working Group.

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of this study was to determine the mortality and re-bleeding rates, and the risk factors involved, in a cohort of patients with previous diverticular bleeding (DB). METHODS:In 2007, data on 2462 patients with lower gastrointestinal (GI) bleeding were collected prospectively at several Frenc...

journal_title：United European gastroenterology journal

authors： Lorenzo D,Gallois C,Lahmek P,Lesgourgues B,Champion C,Charpignon C,Faroux R,Bour B,Remy AJ,Naouri C,Picon M,Poncin E,Macaigne G,Seyrig JA,Bernardini D,Bellaïche G,Grasset D,Henrion J,Heluwaert F,Piperaud R,Bordes

更新日期：2017-02-01 00:00:00

abstract：Background:Hepatorenal syndrome (HRS) is associated with a poor prognosis. In HRS type 1, loss of renal function is rapidly progressive, while HRS type 2 is characterised by chronic ascites and more moderately elevated renal parameters. While treatment with terlipressin/albumin is well established in type 1, its effect...

journal_title：United European gastroenterology journal

authors： Nguyen-Tat M,Jäger J,Rey JW,Nagel M,Labenz C,Wörns MA,Galle PR,Marquardt JU

更新日期：2019-05-01 00:00:00

abstract：Objective:The objective of this article is to evaluate the relationship between off-hours hospital admission (weekends, public holidays or nighttime) and mortality for upper gastrointestinal hemorrhage (UGIH). Methods:Medline, Embase, Scopus, and the Chinese Biomedical Literature were searched through December 2016 to...

journal_title：United European gastroenterology journal

authors： Xia XF,Chiu PWY,Tsoi KKF,Chan FKL,Sung JJY,Lau JYW

更新日期：2018-04-01 00:00:00