Future research demands of the United European Gastroenterology (UEG) and its member societies.

abstract：Background:Hepatic encephalopathy is associated with altered gut microbiota. Proton pump inhibitors increase the risk of small bowel bacterial overgrowth. Objectives:This was a case-control study aimed at exploring the relationship of proton pump inhibitor use with the risk of hepatic encephalopathy during hospitaliza...

journal_title：United European gastroenterology journal

authors： Zhu J,Qi X,Yu H,Yoshida EM,Mendez-Sanchez N,Zhang X,Wang R,Deng H,Li J,Han D,Guo X

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Patients with Crohn's disease (CD) frequently complain of cognitive difficulties such as problems with concentration and clouding of thought, yet this has scarcely been objectively defined and underlying mechanisms remain unknown. OBJECTIVE:The objective of this article is to objectively measure cognitive i...

journal_title：United European gastroenterology journal

authors： van Langenberg DR,Yelland GW,Robinson SR,Gibson PR

更新日期：2017-06-01 00:00:00

abstract：Background:Antibiotic-associated colitis caused by Clostridium difficile (C. difficile) is the most common cause of hospital-acquired diarrhea. The pathogenesis of C. difficile colitis is mediated by bacterial toxins. C. difficile infection (CDI) severity may be determined by the fecal level of these toxins. Objective...

journal_title：United European gastroenterology journal

authors： Cohen NA,Miller T,Na'aminh W,Hod K,Adler A,Cohen D,Guzner-Gur H,Santo E,Halpern Z,Carmeli Y,Maharshak N

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Eosinophilic oesophagitis (EoO) has been associated with allergic disorders as well as aeroallergens. The current literature has shown a possible association between seasonal variation, mainly in the spring, and the incidence of EoO. However, this data was based on small population studies that did not exclu...

journal_title：United European gastroenterology journal

authors： Frederickson NW,Bayman L,Valestin J,Redd M,Lee YJ,Soubra M,Schey R

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND:The incidence of upper gastrointestinal injury by low-dose aspirin (LDA) has increased. OBJECTIVE:We aimed to clarify the risk factors and prevention strategies associated with LDA-induced gastroduodenal ulcer in Japanese patients. METHODS:A retrospective study involving 284 LDA users who underwent oesopha...

journal_title：United European gastroenterology journal

authors： Ito Y,Sasaki M,Noguchi S,Yamaguchi S,Okaniwa N,Tanabe A,Noda H,Yanamoto K,Tamura Y,Kondo Y,Masui R,Izawa S,Iida A,Mizuno M,Ogasawara N,Funaki Y,Kasugai K

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Peroral endoscopic esophageal myotomy (POEM) represents a less invasive alternative, as compared with conventional laparoscopic Heller myotomy for treating achalasia patients. In the last years, a number of prospective and retrospective experiences with POEM use for achalasia have been published. METHODS:Re...

journal_title：United European gastroenterology journal

authors： Barbieri LA,Hassan C,Rosati R,Romario UF,Correale L,Repici A

更新日期：2015-08-01 00:00:00

abstract：Background:Sporadic nonampullary duodenal adenocarcinoma is a rare malignant neoplasm in which poor prognosis is often associated with delayed diagnosis. Objective:A case-control study was designed to evaluate the clinical and endoscopic characteristics of patients with nonampullary duodenal epithelial tumours (NADETs...

journal_title：United European gastroenterology journal

authors： Matsuzaki J,Suzuki H,Shimoda M,Mori H,Fukuhara S,Miyoshi S,Masaoka T,Iwao Y,Kanai Y,Kanai T

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Variable prevalence rates between 2.4 and 35% have been reported for chronic constipation across different countries worldwide, with a low 5% for Germany. OBJECTIVES AND METHODS:We conducted a computer-assisted telephone interview among 15,002 representative individuals in Germany, asking about health-relat...

journal_title：United European gastroenterology journal

authors： Enck P,Leinert J,Smid M,Köhler T,Schwille-Kiuntke J

更新日期：2016-06-01 00:00:00

abstract：Background:The need for a blood transfusion, defined as hemoglobin < 70 g/L, is the measure for assessing the risk levels in patients with upper gastrointestinal bleeding (UGIB). However, not all patients with a low hemoglobin level have a poor prognosis. Objective:We assessed the clinical predictive factors associate...

journal_title：United European gastroenterology journal

authors： Horibe M,Ogura Y,Matsuzaki J,Kaneko T,Yokota T,Okawa O,Nakatani Y,Iwasaki E,Nishizawa T,Hosoe N,Masaoka T,Yahagi N,Namiki S,Kanai T

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Although screening colonoscopy is effective for early detection of colorectal cancer (CRC), screening rates remain low. Multiple factors are thought to be responsible for the low rates of screening colonoscopy, but bowel preparation appears to be a key deterrent. Tolerability issues with bowel preparations m...

journal_title：United European gastroenterology journal

authors： Moshkowitz M,Fokra A,Itzhak Y,Arber N,Santo E

更新日期：2016-02-01 00:00:00

abstract：Background and aims:The aim of this survey was to find out whether the perspectives of patients with inflammatory bowel disease concerning biosimilars have changed since the publication of our last survey carried out in 2014-2015. Methods:An online survey consisting of 19 questions was made available by the European F...

journal_title：United European gastroenterology journal

authors： Peyrin-Biroulet L,Lönnfors S,Avedano L,Danese S

更新日期：2019-12-01 00:00:00

abstract：Background:Cortiment®MMX® (budesonide MMX®) is currently approved for the induction of remission in mild-to-moderate ulcerative colitis (UC) patients when 5-ASA treatment is not sufficient. Data in real-life settings are lacking. Methods:This was a multicentre observational prospective cohort study conducted in Europe...

journal_title：United European gastroenterology journal

authors： Danese S,Hart A,Dignass A,Fiorino G,Louis E,Bonovas S,D'Haens G,Dotan I,Rogler G,Paridaens K,Peyrin-Biroulet L

更新日期：2019-11-01 00:00:00

abstract：:The human microbiota exerts multiple physiological functions such as the regulation of metabolic and inflammatory processes. High-throughput sequencing techniques such as next-generation sequencing have become widely available in preclinical and clinical settings and have exponentially increased our knowledge about th...

journal_title：United European gastroenterology journal

authors： Ammer-Herrmenau C,Pfisterer N,Weingarten MF,Neesse A

更新日期：2020-10-01 00:00:00

abstract：Background:Dysplasia in Barrett's esophagus (BE) biopsies is associated with low observer agreement among general pathologists. Therefore, expert review is advised. We are developing a web-based, national expert review panel for histological review of BE biopsies. Objective:The aim of this study was to create benchmar...

journal_title：United European gastroenterology journal

authors： van der Wel MJ,Duits LC,Klaver E,Pouw RE,Seldenrijk CA,Offerhaus G,Visser M,Ten Kate F,Tijssen JG,Bergman J,Meijer SL

更新日期：2018-07-01 00:00:00

abstract：Background and aims:In complex endoscopies, the initial attempt is often associated with the highest success and subsequent attempts to achieve the same outcome have a higher failure rate. An attending physician needs to decide how the ultimate success may become compromised by letting a fellow start the procedure. A d...

journal_title：United European gastroenterology journal

authors： Sonnenberg A

更新日期：2017-11-01 00:00:00

abstract：Background:Modulating gut microbiota is a potential treatment for irritable bowel syndrome (IBS). This meta-analysis explored whether fecal microbiota transplantation (FMT) is successful in treating IBS. Methods:A systematic review was performed to find trials on FMT in IBS. Ratios and relative ratios (RR) of improvem...

journal_title：United European gastroenterology journal

authors： Myneedu K,Deoker A,Schmulson MJ,Bashashati M

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Recent reports from western countries have indicated an increased incidence and a decreased mortality in acute pancreatitis. However, the incidence assessment has often been hampered by the inclusion of both first-time and recurrent episodes of acute pancreatitis. METHODS:In this retrospective cohort study,...

journal_title：United European gastroenterology journal

authors： Oskarsson V,Hosseini S,Discacciati A,Videhult P,Jans A,Ekbom A,Sadr-Azodi O

更新日期：2020-05-01 00:00:00

abstract：:Stricturing Crohn's disease (CD) is a significant clinical problem. The presence of a stricture may be suggested by clinical symptoms. Cross-sectional imaging using computed tomography or magnetic resonance enterography is essential in diagnosing strictures as it allows further characterization and evaluation for comp...

journal_title：United European gastroenterology journal

authors： El Ouali S,Click B,Holubar SD,Rieder F

更新日期：2020-04-01 00:00:00

abstract：:Eosinophilic esophagitis (EoE) is an emerging esophageal inflammatory disorder affecting children and young adults. As a relatively new disease, EoE is still burdened by frequent diagnostic and therapeutic pitfalls in clinical practice. This manuscript posits a number of similarities with Crohn's disease, which may he...

journal_title：United European gastroenterology journal

authors： Molina-Infante J,Schoepfer AM,Lucendo AJ,Dellon ES

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to investigate the impact of obesity on disease activity and disease outcome in patients with inflammatory bowel disease. PATIENTS AND METHODS:The impact of obesity on inflammatory bowel disease disease activity and outcome was retrospectively assessed in 3075 patients enrolled ...

journal_title：United European gastroenterology journal

authors： Greuter T,Porchet F,Braga-Neto MB,Rossel JB,Biedermann L,Schreiner P,Scharl M,Schoepfer AM,Safroneeva E,Straumann A,Rogler G,Vavricka SR

更新日期：2020-12-01 00:00:00

abstract：:The European Society of Gastrointestinal Endoscopy (ESGE) and United European Gastroenterology (UEG) have a vision to create a thriving community of endoscopy services across Europe, collaborating with each other to provide high quality, safe, accurate, patient-centered and accessible endoscopic care. Whilst the bound...

journal_title：United European gastroenterology journal

authors： Rutter MD,Senore C,Bisschops R,Domagk D,Valori R,Kaminski MF,Spada C,Bretthauer M,Bennett C,Bellisario C,Minozzi S,Hassan C,Rees C,Dinis-Ribeiro M,Hucl T,Ponchon T,Aabakken L,Fockens P

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Primary bile acid diarrhoea (BAD) is associated with increased bile acid synthesis and low fibroblast growth factor 19 (FGF19). Bile acid sequestrants are used as therapy, but are poorly tolerated and may exacerbate FGF19 deficiency. AIM:The purpose of this study was to evaluate the pharmacological effects ...

journal_title：United European gastroenterology journal

authors： Appleby RN,Bajor A,Gillberg PG,Graffner H,Simrén M,Ung KA,Walters J

更新日期：2017-04-01 00:00:00

abstract：Background:Endoscopic mucosal resection is well-established for resecting flat or sessile benign colon polyps. The novel underwater endoscopic mucosal resection eschews submucosal injection prior to endoscopic mucosal resection. Reports about underwater endoscopic mucosal resection were limited to small series of singl...

journal_title：United European gastroenterology journal

authors： Cadoni S,Liggi M,Gallittu P,Mura D,Fuccio L,Koo M,Ishaq S

更新日期：2018-04-01 00:00:00

abstract：:The statements produced by the Consensus Conference on Diverticular Disease promoted by GRIMAD (Gruppo Italiano Malattia Diverticolare, Italian Group on Diverticular Diseases) are reported. Topics such as epidemiology, risk factors, diagnosis, medical and surgical treatment of diverticular disease (DD) in patients wit...

journal_title：United European gastroenterology journal

authors： Cuomo R,Barbara G,Pace F,Annese V,Bassotti G,Binda GA,Casetti T,Colecchia A,Festi D,Fiocca R,Laghi A,Maconi G,Nascimbeni R,Scarpignato C,Villanacci V,Annibale B

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Detection of cholangiocarcinoma (CC) remains a diagnostic challenge particularly in patients with primary sclerosing cholangitis (PSC). We recently established diagnostic peptide marker models in bile and urine to detect CC. Our aim was to combine both models to reach a higher diagnostic accuracy of CC diagn...

journal_title：United European gastroenterology journal

authors： Voigtländer T,Metzger J,Schönemeier B,Jäger M,Mischak H,Manns MP,Lankisch TO

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Multiple medications are associated with an increased risk of incident hepatic encephalopathy. Despite this known risk, medications such as opioids, benzodiazepines, gabapentin/pregabalin, and/or proton pump inhibitors are increasingly prescribed to persons with cirrhosis. Deprescribing is a promisi...

journal_title：United European gastroenterology journal

authors： Williams S,Louissaint J,Nikirk S,Bajaj JS,Tapper EB

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:The risk of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infection and clinical outcomes of coronavirus disease (COVID-19) in inflammatory bowel disease are unclear. METHODS:We searched PubMed and Embase with the keywords: inflammatory bowel disease, Crohn's disease, ulcerative colit...

journal_title：United European gastroenterology journal

authors： Singh AK,Jena A,Kumar-M P,Sharma V,Sebastian S

更新日期：2020-11-19 00:00:00

abstract：Background:Hepatorenal syndrome (HRS) is associated with a poor prognosis. In HRS type 1, loss of renal function is rapidly progressive, while HRS type 2 is characterised by chronic ascites and more moderately elevated renal parameters. While treatment with terlipressin/albumin is well established in type 1, its effect...

journal_title：United European gastroenterology journal

authors： Nguyen-Tat M,Jäger J,Rey JW,Nagel M,Labenz C,Wörns MA,Galle PR,Marquardt JU

更新日期：2019-05-01 00:00:00

abstract：Background:Very few data regarding the use of infliximab in children with very early-onset inflammatory bowel disease (VEO-IBD) have been reported. Objective:We aimed to assess the efficacy and the safety of infliximab in children with VEO-IBD compared with older children. Methods:Children treated with infliximab wer...

journal_title：United European gastroenterology journal

authors： Bramuzzo M,Arrigo S,Romano C,Filardi MC,Lionetti P,Agrusti A,Dipasquale V,Paci M,Zuin G,Aloi M,Strisciuglio C,Miele E,Pastore M,Martelossi S,Alvisi P,SIGENP IBD Working Group.

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIM:The efficacy of clipping for preventing delayed bleeding after colorectal endoscopic resection is still controversial. To assess the efficacy of prophylactic clipping, we conducted a meta-analysis of randomized controlled trials. METHODS:We searched PubMed, the Cochrane library, and the Igaku-chuo-z...

journal_title：United European gastroenterology journal

authors： Nishizawa T,Suzuki H,Goto O,Ogata H,Kanai T,Yahagi N

更新日期：2017-10-01 00:00:00