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A case of congenital long QT syndrome, type 8, undergoing laparoscopic hysterectomy with general anesthesia.

Abstract：

OBJECTIVE:Patients with Long QT syndrome (LQTS) P may present with torsades de pointes, ventricular tachycardia (VT), or ventricular fibrillation (VF) and are at risk of sudden cardiac death. MATERIALS AND METHODS:A 38 y/o female patient with uterus myoma developed VF during laparoscopic assisted vaginal hysterectomy surgery. Defibrillation was delivered and the electrocardiogram (ECG) returned to sinus rhythm after CPR. RESULTS:Patient survived and implantable cardioverter-defibrillator was implanted and received beta-blocker therapy. ECG obtained in out-patient clinic still showed QT interval prolongation, but revealed no prolongation few months after persistent beta-blocker therapy. LQTS type 8 (CACNA1C E768del mutation) was identified by genetic DNA sequencing study. CONCLUSIONS:Patients with concealed LQTS may have normal QT interval unless exposing to stress or specific stimuli. Unexpected ventricular arrhythmia may happen during any medical management. We should avoid triggers of QT prolongation, and get familiar with management of the episode.

journal_name

Taiwan J Obstet Gynecol

journal_title

Taiwanese journal of obstetrics & gynecology

authors

Chang SL,Chang CT,Hung WT,Chen LK

doi

10.1016/j.tjog.2019.05.031

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

552-556

issue

4

eissn

1028-4559

issn

1875-6263

pii

S1028-4559(19)30135-4

journal_volume

58

pub_type

杂志文章

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