Asymptomatic left posterior mediastinal functional paraganglioma: A case report.

Abstract:

RATIONALE:Paraganglioma refers to a set of neuroendocrine tumors derived from the chromaffin cells of the adrenal diplomatic ganglion. Paragangliomas can be classified as functional or nonfunctional based on the ability to synthesize and release catecholamines. PATIENT CONCERNS:We report a 47-year-old man with a functional paraganglioma in the left posterior mediastinum and highlight the key elements of management of mediastinal paragangliomas. DIAGNOSES:A left posterior mediastinal mass was found by computed tomography (CT) scan and Chest-enhanced CT. Preoperative ultrasound-guided biopsy suggested the possibility of a paraganglioma. A diagnosis of paraganglioma was established by immunohistochemistry. INTERVENTIONS:The patient underwent single-stage resection of the lesion via left thoracotomy after preoperative oral α-adrenoceptor (phenoxybenzamine) therapy and intravenous fluid resuscitation for two weeks. OUTCOMES:The postoperative period was uneventful. The patient exhibited no abnormal blood pressure or recurrence during the 12-month follow-up period. LESSONS SUBSECTIONS AS PER STYLE:Pathological examination alone cannot determine whether it was a benign or malignant paraganglioma, which can be determined by pathological examination combined with distant metastasis. Long-term follow-up is required to assess the treatment effect.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Yue Y,Xin H,Li FQ,Wu JD,Liu JZ,Zhang LN

doi

10.1097/MD.0000000000016383

subject

Has Abstract

pub_date

2019-07-01 00:00:00

pages

e16383

issue

28

eissn

0025-7974

issn

1536-5964

pii

00005792-201907120-00053

journal_volume

98

pub_type

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