Abstract:
RATIONALE:Infertile men with Y-chromosome microdeletions have been reported to be able to have their own children via intracytoplasmic sperm injection (ICSI). PATIENT CONCERNS:A 27-year-old man with Y-chromosome azoospermia factor c (AZFc) deletions underwent ICSI treatment. The pregnancy showed a high risk for trisomy 21 syndrome (risk value: 1 in 150). DIAGNOSES:The karyotype of the patient was 46, XY, inv (9) (p11q13). His wife had a normal karyotype. Sequence-tagged site-based polymerase chain reaction (PCR) analysis showed that markers sY254 and sY255 were absent. ICSI was performed. Two embryos (6IV, 8II) were transferred to the uterus of the patient's wife. Second-trimester maternal serum triple-screening showed that the pregnancy was high risk for trisomy 21 syndrome (risk value: 1 in 150). Amniocentesis was performed and revealed that the fetal chromosomal karyotype was 46, XX, inv (9) (p11q13). INTERVENTIONS:The couple chose to continue the pregnancy and a healthy girl was born at 39 weeks of gestation. OUTCOMES:An infertile man with AZFc microdeletions can reproduce via ICSI technology. The karyotype inv (9) (p11q13) can be transmitted to offspring. Whether this karyotype has clinical significance, such as causing infertility or variations in prenatal biochemical markers, is unclear. LESSONS:Y-chromosome microdeletions and/or the karyotype inv (9) (p11q13) may cause clinically significant variation in prenatal biochemical markers.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Hu C,Liu X,Li L,Hu X,Zhu H,Geng D,Liu R,Wang Rdoi
10.1097/MD.0000000000016358subject
Has Abstractpub_date
2019-07-01 00:00:00pages
e16358issue
28eissn
0025-7974issn
1536-5964pii
00005792-201907120-00043journal_volume
98pub_type
杂志文章,评审相关文献
MEDICINE文献大全abstract:RATIONALE:Acute chest pain remains one of the most challenging complaints of patients presenting to emergency departments (EDs). The diverse etiologies of chest pain frequently lead to diagnostic and therapeutic challenges. Esophageal perforation is a rare but potentially life-threatening disease. It results in delayed...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018765
更新日期:2020-01-01 00:00:00
abstract:INTRODUCTION:The Klippel-Trenaunay syndrome (KTS) is a rare congenital disorder. The obstetric course of women with KTS varies. Complications include bleeding, disseminated intravascular coagulation (DIC), thromboembolic events, etc. PATIENT CONCERNS:: Here, we report a case of late puerperal hemorrhage of a Chinese pu...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018378
更新日期:2019-12-01 00:00:00
abstract::Acute acquired concomitant esotropia (AACE) is a rare, distinct subtype of esotropia. The purpose of this retrospective study was to describe the clinical characteristics and discuss the classification and etiology of AACE.Charts from 47 patients with AACE referred to our institute between October 2010 and November 20...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002273
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Low back pain and pelvic girth pain are common in pregnancy and women commonly utilize complementary manual therapies such as massage, spinal manipulation, chiropractic, and osteopathy to manage their symptoms. OBJECTIVE:The aim of this systematically review was to critically appraise and synthesize the bes...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000004723
更新日期:2016-09-01 00:00:00
abstract::The outcome of patients with acute type B aortic dissection (BAAD) is largely dictated by whether or not the case is "complicated." The purpose of this study was to investigate the risk factors leading to in-hospital death among patients with BAAD and then to develop a predictive model to estimate individual risk of i...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016462
更新日期:2019-08-01 00:00:00
abstract:RATIONALE:Orofacial granulomatosis (OFG) is a rare disease characterized by noncaseating granulomatous inflammation. The most common clinical presentation is persistent swelling of the soft tissues in the oral and maxillofacial regions. The precise cause of OFG is unknown. Corticosteroids are the first-line and best tr...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008102
更新日期:2017-09-01 00:00:00
abstract:INTRODUCTION:Acute hydrocephalus is a common complication of spontaneous or traumatic intracranial bleeding with extensive subarachnoid hemorrhage (SAH) or ventricular extension. However, it has never been reported to be secondary to pneumocephalus. PATIENT CONCERNS:A 32-year-old man was admitted following a motorcycl...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018654
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Nutrients related to serum vitamin D level were previously shown to be significantly associated with the risk of many chronic diseases. This study aimed to assess potential relationships between serum vitamin D level and otitis media (OM) risk. METHODS:PubMed, EMBASE, and Cochrane Library databases were sea...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000004739
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVE:The aim of present study is to quantitatively evaluate the association between different interventions and abstinence rates based on network meta-analysis. METHOD:Following PRISMA guidelines, randomized clinical trials that compared different alcoholic interventions for alcohol use disorders associated with ...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000013566
更新日期:2018-12-01 00:00:00
abstract:RATIONALE:Therapeutic or diagnostic thoracentesis is widely used in different clinical settings. Cardiac injury, a rare complication, could lead to fatal consequences. We describe a case of cardiac tamponade complicating thoracentesis that was recognized and rescued in a timely manner. PATIENT CONCERNS:A 42-year-old w...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019778
更新日期:2020-04-01 00:00:00
abstract::Diarrhea-predominant irritable bowel syndrome (IBS-D) and functional diarrhea (FD) are highly prevalent, and the effectiveness of acupuncture for managing IBS-D and FD is still unknown.The aim of this study was to compare the effectiveness of electroacupuncture with loperamide.It was a prospective, randomized, paralle...
journal_title:Medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/MD.0000000000003884
更新日期:2016-06-01 00:00:00
abstract::Enterovirus (EV) infection is common among children and adolescents. Few studies have investigated the relationship of depression after EV infection. This study explores an association between EV infection and subsequent depression in children and adolescents and assesses the risk of depression after EV infection with...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000005983
更新日期:2017-02-01 00:00:00
abstract:RATIONALE:Multiple primary malignancies can occur in the same organ or in multiple organs or systems. Likewise, they can occur simultaneously or successively. Based on the timing of the diagnosis, they are classified as multiple synchronous (i.e., concurrent) or metachronous (i.e., successive) primary malignancies. The...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011107
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Postoperative pain is caused by surgical trauma and poses a significant challenge for health care providers. Opioid analgesics are commonly used to control postoperative pain. However, these drugs are associated with a number of negative side effects. This review will assess the clinical evidence for and aga...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014016
更新日期:2019-01-01 00:00:00
abstract:RATIONALE:Metastasis to the small intestine from a primary lung cancer is rare, and is associated with a poor prognosis. Early diagnosis of small intestine metastasis is difficult because of the low incidence of clinically apparent symptoms. PATIENT CONCERNS:Clinical data and treatment of a 59-year-old man with small ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007768
更新日期:2017-08-01 00:00:00
abstract::Several studies have investigated the incidence of and risk factors for acute exacerbation (AE) in patients with interstitial lung disease (ILD) after lung resection surgery. However, the incidence and risk factors for AE-ILD after non-pulmonary surgery are not known. The aim of this study was to investigate the incid...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000014296
更新日期:2019-02-01 00:00:00
abstract:RATIONALE:The sciatic nerve runs a predictable course combining L4-S3 nerve roots through the true pelvis and under the greater sciatic notch. There are reports of bony protuberances from the sacrum and ilium in cases of spinal dysraphism; however advanced imaging, treatment, or outcomes are not described. There are no...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009770
更新日期:2018-03-01 00:00:00
abstract::Identification of meaningful cluster modules of differential genes or representative biomarkers related to the stages of ovarian cancer (OC) is pivotal, which may help to detect mechanisms of OC progression and evaluate OC patients' prognosis.We downloaded gene expression data and the corresponding clinical informatio...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011895
更新日期:2018-08-01 00:00:00
abstract::Alpha-fetoprotein (AFP) has not played a large role in the surveillance of hepatocellular carcinoma due to inadequate sensitivity and specificity for active chronic hepatitis or cirrhosis. The aim of this study was to evaluate the diagnostic accuracy of AFP in small hepatocellular carcinomas after hepatitis C virus er...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000901
更新日期:2015-06-01 00:00:00
abstract::Whether statin use has any impact on survival of esophageal cancer patients remains controversial. Therefore, we conducted a meta-analysis focusing on current topic for the first time.We systematically searched the following databases for relevant studies comparing survival between statin users and non-users among eso...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000016480
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Chronic liver disease is traditionally conceived as a risk factor for cardiovascular surgery. Transcatheter aortic valve implantation (TAVI) has recently burgeoned to precede surgical aortic valve replacement (SAVR) in patients with severe aortic stenosis at intermediate to high surgical risk. The evidence r...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000019766
更新日期:2020-04-01 00:00:00
abstract::Semantic and verbal fluency tasks are widely used as a measure of frontal capacities. It has been well described in literature that patients affected by schizophrenic and bipolar disorders present a worse execution in these tasks. Some authors have also noted the importance of educational years. Our objective is to an...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001596
更新日期:2015-09-01 00:00:00
abstract::To summarize the clinical features of eyeball rupture with or without orbital fracture and explore the differences between them.In all, 197 patients were observed, and the following data were recorded: sex, age, time of injury, place of injury, cause of trauma, zone of eye injury, intraocular content prolapse, surgica...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007109
更新日期:2017-06-01 00:00:00
abstract:RATIONALE:Invasive moles occur in the fertile period, with about 95% occurring after previous mole removal and the remaining 5% occurring after several other pregnancies. PATIENT CONCERNS:A 27-year-old patient developed a rare invasive mole two months after a missed abortion. DIAGNOSES:A transvaginal ultrasound scan ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017565
更新日期:2019-10-01 00:00:00
abstract::This study is to investigate the subgingival bacterial diversity and community structure in the Uygur subjects with peri-implantitis.Totally 40 cases of gingival crevicular fluid were collected from Uygur subjects and divided into the Control group (healthy implants) and Case group (peri-implantitis), respectively. DN...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009774
更新日期:2018-02-01 00:00:00
abstract::The aim of the study was to evaluate the prognosis and survival of pediatric subjects with chronic intestinal pseudo-obstruction (CIPO) and investigate the independent risk factors affecting their prognosis.This was a retrospective case series of all pediatric subjects suffering from CIPO and treated at the Pediatric ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012150
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Triple negative breast cancer (TNBC) is high-risk due to its rapid drug resistance and recurrence, metastasis, and lack of targeted therapy. So far, no molecularly targeted therapeutic agents have been clinically approved for TNBC. It is imperative that we discover new targets for TNBC therapy. OBJECTIVES:A...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004321
更新日期:2016-07-01 00:00:00
abstract::Idiopathic acute eosinophilic pneumonia (AEP) is an acute febrile illness that may be mistaken for an infectious pneumonia. Patients are often young and otherwise healthy. Clues to considering this disorder in a differential diagnosis include the acuity and severity of the clinical presentation and an initial chest X-...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/00005792-199611000-00004
更新日期:1996-11-01 00:00:00
abstract:RATIONALE:Proprotein convertase subtilisin/kexin 9 or PCSK9 is a protein whose main function is to regulate the number of low-density lipoprotein receptors (LDLR) present on the cell surface. Loss-of-function mutations in PCSK9 have been related to low LDL-cholesterol levels and a decrease in the risk of cardiovascular...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021754
更新日期:2020-08-21 00:00:00
abstract::Chronic inflammation may promote development of coronary heart disease. Studies on the relationship between chronic pancreatitis (CP) and cardiovascular diseases are scant.We conducted a nationwide retrospective cohort study to determine the risk of acute coronary syndrome (ACS) in patients with CP.We randomly selecte...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003451
更新日期:2016-05-01 00:00:00