Reappearance of embryonic neutral alpha-glucosidase isoenzyme in acid maltase-deficient muscle of Japanese quail.

abstract：:Neuropathic pain is common after traumatic injuries to the cauda equina/conus medullaris and brachial plexus. Clinically, this pain is difficult to treat and its mechanisms are not well understood. Lesions to the ventral roots are common in these injuries, but are rarely considered as potential contributors to pain. W...

journal_title：Experimental neurology

authors： Bigbee AJ,Hoang TX,Havton LA

更新日期：2007-03-01 00:00:00

abstract：:Hamsters were inoculated intracerebrally with the agent of transmissible mink encephalopathy and developed clerical signs of encephalopathy. Photoreceptor degeneration occurred in all animals examined histologically. The changes were similar to those in scrapie, although less extensive. The findings suggest that eithe...

journal_title：Experimental neurology

authors： Buyukmihci NC,Goehring-Harmon F,Marsh RF

更新日期：1987-06-01 00:00:00

abstract：:Ciliary neurotrophic factor (CNTF) and brain-derived neurotrophic factor (BDNF) have been shown both in vitro and in vivo to support the survival and differentiation of developing chick or rat motoneurons. To explore the potential use of these and other neurotrophic factors as therapeutic agents in human motoneuron di...

journal_title：Experimental neurology

authors： Kato AC,Lindsay RM

更新日期：1994-12-01 00:00:00

abstract：:The electromyographic (EMG) activity of the gastrocnemius and tibialis anterior muscles was recorded from normal geriatric subjects and from hemiplegic patients subjected to a continuous back-and-forth movement of the platform on which they stood. The platform oscillated at a fixed frequency of 0.5 Hz. Movement amplit...

journal_title：Experimental neurology

authors： Hocherman S,Dickstein R,Hirschbiene A,Pillar T

更新日期：1988-02-01 00:00:00

abstract：:Electrical stimulation of the trigeminal ganglion has been widely used as a model of nociception, characterizing migraine. This treatment is known to evoke release of neuropeptides and neurotransmitters from nerve fibers of the dura mater. On the basis of immunocytochemical investigations, we found that under normal c...

journal_title：Experimental neurology

authors： Knyihár-Csillik E,Chadaide Z,Okuno E,Krisztin-Péva B,Toldi J,Varga C,Molnár A,Csillik B,Vécsei L

更新日期：2004-04-01 00:00:00

abstract：:An in vitro study of the nuclear magnetic resonance (NMR) response of protons in normal and pathological human skeletal muscle is presented. Muscle biopsies from 34 patients with various neuromuscular diseases and five normal subjects were studied by proton NMR techniques and the results were compared with those of li...

journal_title：Experimental neurology

authors： Borghi L,Savoldi F,Scelsi R,Villa M

更新日期：1983-07-01 00:00:00

abstract：:Falls are a major source of hospitalization, long-term institutionalization, and death in older adults and patients with Parkinson's disease (PD). Limited attentional resources are a major risk factor for falls. In this review, we specify cognitive-behavioral mechanisms that produce falls and map these mechanisms onto...

journal_title：Experimental neurology

authors： Sarter M,Albin RL,Kucinski A,Lustig C

更新日期：2014-07-01 00:00:00

abstract：:Cortical and striatal cultures were prepared from the same embryonic rat brains and maintained in identical culture conditions. In this way, the intrinsic, genetically imprinted differences determine the responses of cortical and striatal neurons in comparative studies. Cortical and striatal neurons differed in their ...

journal_title：Experimental neurology

authors： Kovács AD,Cebers G,Cebere A,Moreira T,Liljequist S

更新日期：2001-03-01 00:00:00

abstract：:The behavioral effects of augmenting dopamine D1 receptor expression in the brain were investigated in mice incorporating additional copies of the mouse D1 receptor gene. Two transgenic lines showed increases in brain D1 receptor binding sites, which were greatest in extrastriatal regions. The full D1 agonist SKF 8129...

journal_title：Experimental neurology

authors： Dracheva S,Xu M,Kelley KA,Haroutunian V,Holstein GR,Haun S,Silverstein JH,Sealfon SC

更新日期：1999-05-01 00:00:00

abstract：:Previous work utilizing the 2-deoxyglucose (2-DG) technique demonstrated that denervation, both direct (enucleation) or indirect (retinal receptor destruction, leaving ganglion cells intact), resulted in a depression followed by an increase in glucose metabolism in the superior colliculus (SC) of the mature hooded rat...

journal_title：Experimental neurology

authors： Thurlow GA,Cooper RM

更新日期：1989-06-01 00:00:00

abstract：:Huntington's disease (HD) is an inherited progressive neurodegenerative disorder characterized by progressive movement, psychiatric and cognitive disturbances. Previous studies have indicated that HD pathogenesis may be mediated in part by loss of brain derived neurotrophic factor (BDNF). Antidepressants selectively b...

journal_title：Experimental neurology

authors： Peng Q,Masuda N,Jiang M,Li Q,Zhao M,Ross CA,Duan W

更新日期：2008-03-01 00:00:00

abstract：:Given the prevalence and societal impact of autism spectrum disorders (ASD), there is an urgent need to develop innovative preventative strategies and treatments to reduce the alarming number of cases and improve core symptoms for afflicted individuals. Translational efforts between clinical and preclinical research a...

journal_title：Experimental neurology

authors： Bauman MD,Schumann CM

更新日期：2018-01-01 00:00:00

abstract：:The antiretroviral toxic neuropathy, a distal sensory polyneuropathy associated with antiretroviral treatment, is a frequently occurring neurological complication during treatment of patients with AIDS and often leads to discontinuation of antiretroviral therapy. The mechanisms by which antiretroviral drugs contribute...

journal_title：Experimental neurology

authors： Sanna MD,Peroni D,Quattrone A,Ghelardini C,Galeotti N

更新日期：2015-05-01 00:00:00

abstract：:Rats were injected with capsaicin or solvent on the 2nd day of life. Nine weeks later both animal groups were further subdivided: one was untreated and the other group underwent surgery consisting in either (a) removal of one sternohyoid superior muscle or (b) a sham operation. The sternohyoid superior muscles were re...

journal_title：Experimental neurology

authors： Müntener M

更新日期：1985-04-01 00:00:00

abstract：:The extracellular signal-regulated kinase 1 and 2 (ERK) pathway, regulated by phosphorylation on specific amino acids, is emerging as an important signaling cascade in neurones, transducing sensory input into cellular responses. In the mammalian nervous system, the ERK pathway has been found to mediate plasticity even...

journal_title：Experimental neurology

authors： Cruz CD,McMahon SB,Cruz F

更新日期：2006-07-01 00:00:00

abstract：:Oxidative stress has been implicated in several neurodegenerative diseases affecting both neuronal and glial cells. The aim of this study was to investigate the involvement of reactive oxygen species in glutamate-evoked activation of NF-kappaB in primary astrocytes. A prolonged exposure to glutamate (24 h) caused a de...

journal_title：Experimental neurology

authors： Caccamo D,Campisi A,Marini H,Adamo EB,Li Volti G,Squadrito F,Ientile R

更新日期：2005-06-01 00:00:00

abstract：:Graft-induced dyskinesia has emerged as a problematic side effect after transplantation of fetal dopamine cells into the striatum of patients with Parkinson's disease. These adverse effects of dystonic and choreatiform hyperkinesias that persisted even after withdrawal of L-DOPA medication are not yet fully understood...

journal_title：Experimental neurology

authors： García J,Carlsson T,Döbrössy M,Nikkhah G,Winkler C

更新日期：2011-12-01 00:00:00

abstract：:Idiopathic inflammatory myopathies (IIMs), comprising of polymyositis, dermatomyositis, and inclusion-body myositis, are characterized by muscle weakness and various types of inflammatory changes in muscle cells. They also show non-inflammatory changes, including perifascicular atrophy, mitochondrial changes, and amyl...

journal_title：Experimental neurology

authors： Nozaki K,Das A,Ray SK,Banik NL

更新日期：2010-10-01 00:00:00

abstract：:Mutations in the human NOTCH3 gene cause cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), but the pathogenesis of CADASIL has remained unclear. Recently, endocytosis of the Notch ectodermal domain into ligand-expressing cells, called transendocytosis, has come to be...

journal_title：Experimental neurology

authors： Watanabe-Hosomi A,Watanabe Y,Tanaka M,Nakagawa M,Mizuno T

更新日期：2012-01-01 00:00:00

abstract：:Myelin accelerates action potential conduction velocity and provides essential energy support for axons. Unfortunately, myelin and myelinating cells are often vulnerable to injury or disease, resulting in myelin damage, which in turn can lead to axon dysfunction, overt pathology and neurological impairment. Inflammati...

journal_title：Experimental neurology

authors： Goldstein EZ,Church JS,Hesp ZC,Popovich PG,McTigue DM

更新日期：2016-09-01 00:00:00

abstract：:Triggering receptor expressed on myeloid cells-2 (TREM2) was a newly identified receptor expressed on microglia. Several observations support the hypothesis that TREM2 variation may confer susceptibility to Parkinson's disease (PD). Therefore, in this paper, we explored the role of TREM2 in the 1-methyl-4-phenyl-1,2,3...

journal_title：Experimental neurology

authors： Ren M,Guo Y,Wei X,Yan S,Qin Y,Zhang X,Jiang F,Lou H

更新日期：2018-04-01 00:00:00

abstract：:It has been suggested that the increased transient expression of immediate-early gene transcription factors seen in nerve cells following an afterdischarge may initiate longer lasting or permanent changes in gene expression which underly the development of kindling. Since the development of kindling is sensitive to ph...

journal_title：Experimental neurology

authors： Hughes P,Singleton K,Dragunow M

更新日期：1994-08-01 00:00:00

abstract：:In the intraluminal suture model of middle cerebral artery occlusion (MCAO) in the rat, lesions of the masticator muscles associated with impaired functional outcome occur. We evaluated the role of external carotid artery (ECA) transection. We assessed whether isolated interruption of an arterial or a venous connectio...

journal_title：Experimental neurology

authors： Dittmar MS,Vatankhah B,Fehm NP,Retzl G,Schuierer G,Bogdahn U,Schlachetzki F,Horn M

更新日期：2005-10-01 00:00:00

abstract：:The kindling phenomenon, i.e., the progressive development of focal and secondarily generalized seizures upon repeated electrical stimulation of a limbic brain region, occurs in various species, but with marked differences in kindling rate between species and also within the same species. In rats, differences in kindl...

journal_title：Experimental neurology

authors： Löscher W,Cramer S,Ebert U

更新日期：1998-12-01 00:00:00

abstract：:The threshold current required for the excitation of visual cortex neurons in the vicinity (approximately 1 mm) of an intracortical stimulating electrode was measured as a function of the stimulus pulse duration in the anesthetized cat. For cortical neurons with latencies of activation from 0.4 to 3.4 ms and for stimu...

journal_title：Experimental neurology

authors： Ronner SF,Lee BG

更新日期：1983-08-01 00:00:00

abstract：:Functional regeneration of brainstem-spinal pathways occurs in the developing chick when the spinal cord is severed prior to embryonic day (E) 13. Functional spinal cord regeneration is not observed in animals injured after E13. This developmental transition from a permissive to a restrictive repair period may be due ...

journal_title：Experimental neurology

authors： Borisoff JF,Pataky DM,McBride CB,Steeves JD

更新日期：2000-11-01 00:00:00

abstract：:Seizures were induced in immature 18-day-old rats by i.p. administration of homocysteine (11 mmol/kg) and the effects of selected antagonists of NMDA receptors [MK-801 (0.5 mg/kg), AP7 (0.33 mmol/kg), CGP 40116 (10 mg/kg)] and non-NMDA receptors [GDEE (4 mmol/kg), NBQX (two doses, 30 mg/kg each)] were studied. The eff...

journal_title：Experimental neurology

authors： Folbergrová J

更新日期：1997-06-01 00:00:00

abstract：:Crush of sciatic nerve in rabbits supported by morphologic and electrophysiologic data was used to evaluate the effects of ACTH4-10 on nerve fiber regeneration. Treated animals showed a statistically significant higher regeneration rate than did control rabbits. Fiber density and mean diameters of myelinated nerve fib...

journal_title：Experimental neurology

authors： Girlanda P,Muglia U,Vita G,Dattola R,Santoro M,Toscano A,Venuto C,Roberto ML,Baradello A,Romano M

更新日期：1988-02-01 00:00:00

abstract：:The amount of myelination in vivo and in vitro depends on the number of oligodendrocyte progenitors, their differentiation, and on the neuron function. It has been shown that continuous administration of FGF2, a mitotic and neuroprotective factor, allows oligodendrocyte progenitors to proliferate, but prevents them fr...

journal_title：Experimental neurology

authors： Magy L,Keita M,Richard L,Piaser M,Vallat JM

更新日期：2003-05-01 00:00:00

abstract：:Cholinergic neurons in the basal forebrain magnocellular complex (BFMC) respond to nerve growth factor (NGF) during development and in adult life, and it has been suggested that the administration of NGF might ameliorate some of the abnormalities that occur in neurological disorders associated with degeneration of thi...

journal_title：Experimental neurology

authors： Koliatsos VE,Applegate MD,Knüsel B,Junard EO,Burton LE,Mobley WC,Hefti FF,Price DL

更新日期：1991-05-01 00:00:00