Antioxidant Properties of Solenostemma argel Effervescent Tablets.

abstract：AIM OF THE STUDY:To assess tramadol and O-desmethyltramadol (M1) concentrations and their correlations with analgesia in patients with cancer pain. PATIENTS AND METHODS:Thirty opioid-naive patients with nociceptive pain intensity on VAS (visual analogue scale) > 40 received controlled-release tramadol as the first (15...

journal_title：Current pharmaceutical biotechnology

authors： Leppert W,Mikolajczak P

更新日期：2011-02-01 00:00:00

abstract：:A novel steroidal oxime (SO) was synthesized using an economic method and then characterized by Fourier transform infrared (FTIR) and 1H nuclear magnetic resonance (NMR). When dispersed in pure water, SO can self-assemble into a nano-scale circular structure which was verified by dynamic light scattering (DLS) and tra...

journal_title：Current pharmaceutical biotechnology

authors： Chou TH,Chen CW

更新日期：2015-01-01 00:00:00

abstract：:Until recently, most research efforts aimed at developing anti-cancer tools were focusing on small molecules. Alternative compounds are now being increasingly assessed for their potential anti-cancer properties, including peptides and their derivatives. One earlier limitation to the use of peptides was their limited c...

journal_title：Current pharmaceutical biotechnology

authors： Barras D,Widmann C

更新日期：2011-08-01 00:00:00

abstract：:Even though malnutrition is associated with an adverse prognosis after allogeneic stem cell transplantation, few studies have addressed the question what is the optimal nutritional support for these patients. There is a general agreement that the body weight, body mass index and nutritional intake can be used to guide...

journal_title：Current pharmaceutical biotechnology

authors： Tvedt TH,Reikvam H,Bruserud Ø

更新日期：2016-01-01 00:00:00

abstract：: ...

journal_title：Current pharmaceutical biotechnology

authors： Blum K,Baron D

更新日期：2019-01-01 00:00:00

abstract：:The aim of the present article was to review the role of the placenta function in the transfer of immunosuppressants and monoclonal antibodies used for the treatment of inflammatory bowel disease, as well as the available data regarding the safety of these therapies during pregnancy. Methotrexate can cause congenital ...

journal_title：Current pharmaceutical biotechnology

authors： Chaparro M,Gisbert JP

更新日期：2011-05-01 00:00:00

abstract：:A variety of technologies can be used in the detection of contagious pathogens. In the early stage of an outbreak of a new infectious disease, rtPCR is advantageous over many other assays. The rtPCR can be developed either using low fidelity DNA polymerase or high fidelity DNA polymerase. The application of high fidel...

journal_title：Current pharmaceutical biotechnology

authors： Li K,Xiao L,Liu C,Zhang J,Sirois P

更新日期：2010-01-01 00:00:00

abstract：:Unlike any other cell type, T cells have a unique potential to eliminate cancer cells and to eventually cure cancer patients. As a result, researchers have made extensive efforts over the past three decades to develop therapeutics with the potential to mount T cell responses against cancer cells. One way in which such...

journal_title：Current pharmaceutical biotechnology

authors： Baeuerle PA,Itin C

更新日期：2012-06-01 00:00:00

abstract：:Long-term increase of blood pressure represents one of the most important risk factors triggering many cardiovascular diseases, and via counter-regulatory mechanisms it is itself modulated by them. Adequate perfusion of the respective areas with nutrients requires appropriate production of vasodilatory and vasoconstri...

journal_title：Current pharmaceutical biotechnology

authors： Kristek F

更新日期：2011-09-01 00:00:00

abstract：:The blood-brain barrier (BBB), which impedes drug penetration into the central nervous system, is composed of specific structures formed by brain capillary endothelial cells and sheathed by astrocytic end-feet through basement membrane. Many brain drug delivery strategies have focused on adsorptive-mediated transcytos...

journal_title：Current pharmaceutical biotechnology

authors： Lu W

更新日期：2012-09-01 00:00:00

abstract：:Raman spectroscopy has long been used as a powerful tool for chemical composition analyses. Raman scattering light measurement has the advantage of being able to examine biomolecules in a nondestructive and non-labeling manner. However, molecular imaging of cells and tissues by using Raman microscopy had been hampered...

journal_title：Current pharmaceutical biotechnology

authors： Harada Y,Takamatsu T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Despite the extended laboratory and clinical study of sepsis, its diagnosis remains a clinical challenge. The initiation of sepsis activates many different biochemical and immunological pathways being expressed by alterations of various molecules in human tissues. The detection and measurement of the concent...

journal_title：Current pharmaceutical biotechnology

authors： Giannakopoulos K,Hoffmann U,Ansari U,Bertsch T,Borggrefe M,Akin I,Behnes M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:`Herbal mixtures` containing synthetic cannabinoid receptor agonists (SCRAs) are promoted as legal alternative to marihuana and are easily available via the Internet. Keeping analytical methods for the detection of these SCRAs up-to-date is a continuous challenge for clinicians and toxicologists due to the h...

journal_title：Current pharmaceutical biotechnology

authors： Hutter M,Broecker S,Kneisel S,Franz F,Brandt SD,Auwarter V

更新日期：2018-01-01 00:00:00

abstract：:Natural compounds represent a significant source for the development of novel medicines. Finding the target proteins for a natural compound is the most important step towards understanding its molecular mechanism for therapeutic usage. In fact, the search for target proteins could be considered the first step of the d...

journal_title：Current pharmaceutical biotechnology

authors： Yao L

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Sexual dysfunction and infertility are conditions with high prevalence in the general population. Nutritional factors have been reported to have an impact on sexual and reproductive health. OBJECTIVE:The aim of this review is to summarize the data on nutritional factors that have influence on male and femal...

journal_title：Current pharmaceutical biotechnology

authors： Silva T,Jesus M,Cagigal C,Silva C

更新日期：2019-01-01 00:00:00

abstract：:The clinical recognition and adequate treatment of women with hyperglycemia during pregnancy is significant in order to reduce neonatal complications correlated with gestational diabetes mellitus (GDM). The traditional management of pregnant patients with GDM in whom diet restriction is not sufficient enough involves ...

journal_title：Current pharmaceutical biotechnology

authors： Kimber-Trojnar Ż,Marciniak B,Patro-Malysza J,Skorzynska-Dziduszko K,Poniedzialek-Czajkowska E,Mierzynski R,Galczynski K,Trojnar M,Leszczynska-Gorzelak B,Oleszczuk J

更新日期：2014-01-01 00:00:00

abstract：:X-ray is a non-thermal technology that has shown good efficacy in reducing pathogenic and spoilage bacteria, viruses and parasites. X-ray hygiene technology resulted in a high microbial loss in numerous food products, such as dairy products, ready-to-eat shrimp, oysters, fresh products, strawberries, shredded iceberg ...

journal_title：Current pharmaceutical biotechnology

authors： Zehi ZB,Afshari A,Noori SMA,Jannat B,Hashemi M

更新日期：2020-01-01 00:00:00

abstract：:Mammalian cell lines are important host cells for the industrial production of pharmaceutical proteins owing to their capacity for correct folding, assembly and post-translational modification. In particular, Chinese hamster ovary (CHO) cells are the most dependable host cells for the industrial production of therapeu...

journal_title：Current pharmaceutical biotechnology

authors： Omasa T,Onitsuka M,Kim WD

更新日期：2010-04-01 00:00:00

abstract：:Data obtained through high-throughput technologies have gradually revealed that a unique stratified epithelial architecture of human skin along with the antioxidant-response pathways provided vital defensive mechanisms against UV radiation. However, it is noteworthy that skin is a major target for toxic insult by UV r...

journal_title：Current pharmaceutical biotechnology

authors： Farooqi AA,Li RN,Huang HW,Ismail M,Yuan SS,Wang HM,Liu JR,Tang JY,Chang HW

更新日期：2015-01-01 00:00:00

abstract：:Recent research has shown that the endogenous gas hydrogen sulphide (H2S) is a signalling molecule of considerable biological potential and has been suggested to be involved in a vast number of physiological processes. In the vascular system, H2S is synthesized from cysteine by cystathionine-γ-lyase (CSE) in smooth mu...

journal_title：Current pharmaceutical biotechnology

authors： Skovgaard N,Gouliaev A,Aalling M,Simonsen U

更新日期：2011-09-01 00:00:00

abstract：:In order to valorize novel biotechnology innovations, there is a need to evaluate ex-ante their market potential. A case in point is biofortification, i.e. the enhancement of the micronutrient content of staple crops through conventional or genetic breeding techniques. In a recent article in Nature Biotechnology, for ...

journal_title：Current pharmaceutical biotechnology

authors： De Steur H,Blancquaert D,Gellynck X,Lambert W,Van Der Straeten D

更新日期：2012-12-01 00:00:00

abstract：:Most cancer patients will experience moderate to severe pain and/or neuropathy during the course of their disease. Recent improvements in the primary treatment of cancer have increased the life span of cancer patients, but not necessarily their quality of life (QoL). The pain and suffering cancer patients experience m...

journal_title：Current pharmaceutical biotechnology

authors： Knopp KL,Nisenbaum ES,Arneric SP

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is a primary liver cancer with high mortality. Paeoniflorin is a pinane monoterpene picroside with anti-tumor effect isolated from Chinese peony root and white peony root. OBJECTIVE:To investigate the underlying mechanism of paeoniflorin (PF) regulating hepatocellular carcinom...

journal_title：Current pharmaceutical biotechnology

authors： Zhou Y,Liu X,Gao Y,Tan R,Wu Z,Zhong Q,Zeng F

更新日期：2020-10-09 00:00:00

abstract：BACKGROUND:Burn is still an important global public health challenge. Wound colonization of antibiotic resistant bacteria such as Acinetobacter baumannii can lead to high morbidity and mortality in burn patients. The aim of this study was to evaluate the inhibitory effect of tazobactam on efflux pump, which can cause a...

journal_title：Current pharmaceutical biotechnology

authors： Azimi L,Tahbaz SV,Alaghehbandan R,Alinejad F,Lari AR

更新日期：2020-01-01 00:00:00

abstract：:Charged-hydrophobic mixed mode chromatography methods have been applied to antibody purification for decades and have focused more recently on the specific task of aggregate removal. They exploit various combinations of alkyl and aromatic hydrophobic groups with positively and/or negatively charged residues. Charge an...

journal_title：Current pharmaceutical biotechnology

authors： Gagnon P

更新日期：2009-06-01 00:00:00

abstract：:Whole-cell bio-chips for functional sensing integrate living cells on miniaturized platforms made by micro-system-technologies (MST). The cells are integrated, deposited or immersed in a media which is in contact with the chip. The cells behavior is monitored via electrical, electrochemical or optical methods. In this...

journal_title：Current pharmaceutical biotechnology

authors： Shacham-Diamand Y,Belkin S,Rishpon J,Elad T,Melamed S,Biran A,Yagur-Kroll S,Almog R,Daniel R,Ben-Yoav H,Rabner A,Vernick S,Elman N,Popovtzer R

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Although the stability of proteins is of significance to maintain protein function for therapeutical applications, this remains a challenge. Herein, a general method of preserving protein stability and function was developed using gelatin films. METHODS:Enzymes immobilized onto films composed of gelatin and...

journal_title：Current pharmaceutical biotechnology

authors： Zhang L,Shen Y,Lu W,Guo L,Xiang M,Zhang D

更新日期：2020-01-01 00:00:00

abstract：:In recent years, many systems biology approaches have been used with various cancers. The materials described here can be used to build bases to discover novel cancer therapy targets in connection with computer-aided drug design (CADD). A deeper understanding of the mechanisms of cancer will provide more choices and c...

journal_title：Current pharmaceutical biotechnology

authors： Wong YH,Chiu CC,Lin CL,Chen TS,Jheng BR,Lee YC,Chen J,Chen BS

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Large-scale population studies showed that the SNP rs1764391 of Connexin37 gene also known as Cx37 gene may play a pivotal role in the occurrence and development of acute myocardial infarction (AMI). Published results, however, are highly controversial. OBJECTIVE:This study aimed to examine the association ...

journal_title：Current pharmaceutical biotechnology

authors： Li J,Qin R,Wang W,Huang Z,Huang DL,Li T,Wang F,Zeng XT,Sun ZY,Liu XF,Huang F,Guo T

更新日期：2020-01-01 00:00:00

abstract：:Apolipoprotein M (apoM) has been suggested to play a role in reverse cholesterol transport. Here we studied the influence of liver X-receptor (LXR) agonist on the transcriptional regulation of apoM. Studies were performed in murine liver and intestinal mucosal cells in vivo and in human intestinal Caco-2 cells in vitr...

journal_title：Current pharmaceutical biotechnology

authors： Calayir E,Becker TM,Kratzer A,Ebner B,Panzenböck U,Stefujl J,Kostner GM

更新日期：2008-12-01 00:00:00