Heterogeneity of Macrophages in Atherosclerosis.

Abstract:

:Atherosclerosis is a prevalent inflammatory condition and a frequent cause of morbidity and mortality worldwide. Macrophages are among the key immune cells driving lesion formation in the arterial wall. They have therefore evolved as potential targets for therapeutic strategies. Understanding of the different macrophage phenotypes and functions seems to be of pivotal importance for the development of treatments to target these immune cells. This review highlights the complexity of the mononuclear phagocyte system and summarizes important features of macrophage biology contributing to atherosclerosis.

journal_name

Thromb Haemost

authors

Stremmel C,Stark K,Schulz C

doi

10.1055/s-0039-1692665

subject

Has Abstract

pub_date

2019-08-01 00:00:00

pages

1237-1246

issue

8

eissn

0340-6245

issn

2567-689X

journal_volume

119

pub_type

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