Variable opportunities for outcrossing result in hotspots of novel genetic variation in a pathogen metapopulation.

Abstract:

:Many pathogens possess the capacity for sex through outcrossing, despite being able to reproduce also asexually and/or via selfing. Given that sex is assumed to come at a cost, these mixed reproductive strategies typical of pathogens have remained puzzling. While the ecological and evolutionary benefits of outcrossing are theoretically well-supported, support for such benefits in pathogen populations are still scarce. Here, we analyze the epidemiology and genetic structure of natural populations of an obligate fungal pathogen, Podosphaera plantaginis. We find that the opportunities for outcrossing vary spatially. Populations supporting high levels of coinfection -a prerequisite of sex - result in hotspots of novel genetic diversity. Pathogen populations supporting coinfection also have a higher probability of surviving winter. Jointly our results show that outcrossing has direct epidemiological consequences as well as a major impact on pathogen population genetic diversity, thereby providing evidence of ecological and evolutionary benefits of outcrossing in pathogens.

journal_name

Elife

journal_title

eLife

authors

Laine AL,Barrès B,Numminen E,Siren JP

doi

10.7554/eLife.47091

subject

Has Abstract

pub_date

2019-06-18 00:00:00

issn

2050-084X

pii

47091

journal_volume

8

pub_type

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