Association of Virologic Failure and Nonnucleoside Reverse Transcriptase Inhibitor Resistance Found in Antiretroviral-Naive Children Infected With Human Immunodeficiency Virus and Given Efavirenz-Based Treatment.

abstract：Background:Trichosporonosis is an emerging and often fatal opportunistic fungal infection in immunocompromised patients, particularly those with hematologic malignancy, but data in children are lacking. Methods:We report here 3 cases of invasive infection caused by Trichosporon asahii in pediatric patients with acute ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Foster CE,Edwards MS,Brackett J,Schady DA,Healy CM,Baker CJ

更新日期：2018-08-17 00:00:00

abstract：BACKGROUND:Children who develop malaria after returning to a setting in which the disease is not endemic are at high risk for critical delays in diagnosis and initiation of antimalarial therapy. We assessed the clinical impact of the implementation of malaria rapid diagnostic testing (RDT) on the management of children...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Enane LA,Sullivan KV,Spyridakis E,Feemster KA

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Scrub typhus, caused by Orientia tsutsugamushi, is a major cause of acute febrile illness in children in the rural tropics. METHODS:We recruited 60 febrile pediatric patients with a positive scrub typhus rapid diagnostic test result and 40 healthy controls from Chiang Rai Province in northern Thailand. Diag...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wangrangsimakul T,Greer RC,Chanta C,Nedsuwan S,Blacksell SD,Day NPJ,Paris DH

更新日期：2020-04-30 00:00:00

abstract：BACKGROUND:Parechovirus A (PeV-A) is an important cause of sepsis and meningoencephalitis in neonates and young infants. Thus, identifying the source of PeV-A is essential for prevention; however, little is known regarding the spread of PeV-A among family members of PeV-A-infected neonates and young infants. METHODS:I...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Izumita R,Deuchi K,Aizawa Y,Habuka R,Watanabe K,Otsuka T,Saitoh A

更新日期：2019-12-27 00:00:00

abstract：OF KEY POINTS:Although relatively rare, invasive meningococcal disease continues to be a health concern, especially in young children. This systematic review clearly delineates both the near- and long-term morbidities that can occur after, and persist beyond, the period of acute illness. BACKGROUND:Although rare, inva...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Strifler L,Morris SK,Dang V,Tu HA,Minhas RS,Jamieson FB,Deeks SL,Crowcroft NS,Sander B

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Rotavirus is the most common cause of infectious diarrhea in children worldwide. Recent studies have described changes in the burden of all-cause gastroenteritis; however, there are limited data on the clinical and economic impact of rotavirus vaccine on cases of laboratory-confirmed rotavirus disease. METH...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Guerra AH,Stockmann C,Pavia AT,Hersh AL,Thorell EA,Weng HY,Korgenski K,Byington CL,Ampofo K

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:In theory, active surveillance of methicillin-resistant Staphylococcus aureus (MRSA) reduces MRSA spread by identifying all MRSA-colonized patients and placing them under contact precautions. In October 2007, Illinois mandated active MRSA surveillance in all intensive care units, including neonatal intensive...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Lyles RD,Trick WE,Hayden MK,Lolans K,Fogg L,Logan LK,Shulman ST,Weinstein RA,Lin MY,Centers for Disease Control and Prevention, Prevention Epicenters Program.

更新日期：2016-12-01 00:00:00

abstract：Background:Children undergoing CIC frequently have positive urine culture results and receive many antimicrobial agents. Subsequently, this population is at high risk for infections caused by antimicrobial-resistant bacteria. Resistant pathogens, such as vancomycin-resistant Enterococcus (VRE), carbapenem-resistant Ent...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Forster CS,Courter J,Jackson EC,Mortensen JE,Haslam DB

更新日期：2017-11-24 00:00:00

abstract：BACKGROUND:The transmission of human immunodeficiency virus (HIV) among youth through high-risk behaviors continues to increase. Retention in Care is associated with positive clinical outcomes and a decrease in HIV transmission risk behaviors. We evaluated the clinical and demographic characteristics of non-perinatally...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Farmer C,Yehia BR,Fleishman JA,Rutstein R,Mathews WC,Nijhawan A,Moore RD,Gebo KA,Agwu AL,HIV Research Network.

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:The 2017-2018 influenza season was of high severity. Circulating influenza strains change periodically, making it important to determine vaccine effectiveness on an annual basis, especially for susceptible populations. The primary aim of our study was to estimate the effectiveness of the influenza vaccine am...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Powell LN,Bégué RE

更新日期：2020-09-17 00:00:00

abstract：BACKGROUND:Respiratory viruses cause significant morbidity and death in infants; 99% of such deaths occur in resource-limited settings. Risk factors for initial and repeated respiratory viral infections in young infants in resource-limited settings have not been well described. METHODS:From 2011 to 2014, a birth cohor...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Boonyaratanakornkit J,Englund JA,Magaret AS,Bu Y,Tielsch JM,Khatry SK,Katz J,Kuypers J,Shrestha L,LeClerq SC,Steinhoff MC,Chu HY

更新日期：2020-02-28 00:00:00

abstract：:Among newborns with congenital cytomegalovirus (CMV) infection from China, there was no difference in CMV viral load in saliva specimens dried and stored at room temperature compared with those kept wet and stored cold, even after longer storage time for the former than the later (74 vs 58 days, P = .02). ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Xu A,Wang S,Zhang W,Wang X,Wang T,Liu X,Wang H,Ma W,Amin M,Dollard S,Wang C

更新日期：2018-08-17 00:00:00

abstract：:E-consults replace "curbside" interactions, facilitate provider-specialist communication, document within the medical record, and track relative value units (RVUs). Pediatric infectious diseases (PID) E-consults commonly relate to vaccines, exposures, diagnoses, and treatments. The documented RVU effort of 197 consecu...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Gonzalez BE,Sabella C,Esper FP,Daniels HL,Saracusa C,Boutros J,Foster CB

更新日期：2020-05-05 00:00:00

abstract：BACKGROUND:In November 2020, the US Food and Drug Administration (FDA) provided Emergency Use Authorizations (EUA) for two novel virus-neutralizing monoclonal antibody therapies, bamlanivimab, and REGN-COV2 (casirivimab plus imdevimab), for the treatment of mild to moderate COVID-19 in adolescents and adults in specifi...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wolf J,Abzug MJ,Wattier RL,Sue PK,Vora SB,Zachariah P,Dulek DE,Waghmare A,Olivero R,Downes KJ,James SH,Pinninti SG,Yarbrough A,Aldrich ML,MacBrayne CE,Soma VL,Grapentine SP,Oliveira CR,Hayes M,Kimberlin DW,Jones S

更新日期：2021-01-03 00:00:00

abstract：BACKGROUND:Single-nucleotide polymorphisms (SNPs) in the fucosyltransferase genes FUT2 and FUT3 have been associated with susceptibility to various infectious and inflammatory disorders. FUT variations influence the expression of human histo-blood group antigens (HBGAs) (H-type 1 and Lewis), which are highly expressed ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： King JR,Varadé J,Hammarström L

更新日期：2019-12-27 00:00:00

abstract：Key points:The effectiveness of pentavalent rotavirus vaccine against rotavirus-associated hospitalization was more than 90% 4 years after introduction into the national immunization program in Finland. A major impact on hospitalization for all-cause gastroenteritis was observed also. Background:Rotavirus vaccination ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Hemming-Harlo M,Vesikari T,Uhari M,Renko M,Salminen M,Torcel-Pagnon L,Hartwig S,Simondon F,Bricout H

更新日期：2017-11-24 00:00:00

abstract：:Coronavirus disease (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians in China reported what is believed to be the first adult case of a SARS-CoV-2 infection associated with acute Guillain-Barré syndrome (GBS), followed by 5 adult Italian patients and anoth...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Khalifa M,Zakaria F,Ragab Y,Saad A,Bamaga A,Emad Y,Rasker JJ

更新日期：2020-09-17 00:00:00

abstract：Background:Pseudomonas aeruginosa is a common cause of healthcare-associated infection. Multidrug-resistant (MDR) (>3 classes) and carbapenem-resistant (CR) P aeruginosa are significant threats globally. We used a large reference-laboratory database to study the epidemiology of P aeruginosa in children in the United St...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Logan LK,Gandra S,Mandal S,Klein EY,Levinson J,Weinstein RA,Laxminarayan R,Prevention Epicenters Program, US Centers for Disease Control and Prevention.

更新日期：2017-11-24 00:00:00

abstract：:Across 12 consecutive influenza seasons in Utah, medically-attended visits for laboratory-confirmed influenza infection peaked first among older children (12-18 years). Peak activity in older children preceded that of children 0-4 years by more than 2 days and that of peak activity among adults ≥65 years by more than ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Stockmann C,Pavia AT,Hersh AL,Spigarelli MG,Castle B,Korgenski K,Byington CL,Ampofo K

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The objective was to describe respiratory syncytial virus (RSV) hospitalizations in Alberta, Canada over a 13-year period with an emphasis on the incidence and risk factors for repeat hospitalizations attributable to new RSV infections. METHODS:This was a retrospective database analysis. The Alberta Health ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Wong K,Robinson JL,Hawkes MT

更新日期：2020-07-24 00:00:00

abstract：BACKGROUND:The clinical and economic outcomes associated with pediatric antimicrobial stewardship programs (ASPs) and other supplemental antimicrobial stewardship (AS) interventions have not been well described or reviewed. METHODS:We performed a systematic review using PubMed to identify studies with any of the follo...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Smith MJ,Gerber JS,Hersh AL

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:P1093 is an ongoing phase I/II multicenter open-label study of dolutegravir plus an optimized background regimen in age-defined pediatric cohorts; here we report the long-term safety and virologic efficacy outcomes for the oldest cohort. METHODS:The study enrolled human immunodeficiency virus type 1 (HIV-1)...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Viani RM,Ruel T,Alvero C,Fenton T,Acosta EP,Hazra R,Townley E,Palumbo P,Buchanan AM,Vavro C,Singh R,Graham B,Anthony P,George K,Wiznia A,P1093 Study Team .

更新日期：2020-04-30 00:00:00

abstract：:Little information on the efficacy and pharmacokinetics of letermovir among immunocompromised children is currently available. We describe here the use of letermovir in a 2-year-old immunocompromised child with ganciclovir-resistant cytomegalovirus disease who required extracorporeal membrane oxygenation. Detailed inf...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Pérez Marín M,Decosterd LA,Andre P,Buclin T,Mercier T,Murray K,Rizzi M,Meylan P,Jaton-Ogay K,Opota O,Gengler C,Perez MH,Natterer J,Asner SA

更新日期：2020-02-28 00:00:00

abstract：Background:Data on long-term toxicity of antiretroviral therapy (ART) in HIV-infected children are sparse. PENPACT-1 was an open-label trial in which HIV-infected children were assigned randomly to receive protease inhibitor (PI)- or nonnucleoside reverse-transcriptase inhibitor (NNRTI)-based ART. Methods:We examined ...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Melvin AJ,Warshaw M,Compagnucci A,Saidi Y,Harrison L,Turkova A,Tudor-Williams G,PENPACT-1 (PENTA 9\/PACTG 390\/ANRS 103) Study Team.

更新日期：2017-09-01 00:00:00

abstract：:The reduction in human immunodeficiency virus (HIV) transmission through breastmilk with maternal combination antiretroviral therapy (cART) has led many pregnant women living with HIV and healthcare providers to question exclusive formula feeding in resource-rich settings. Here, we describe cART prophylaxis in 3 breas...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Nashid N,Khan S,Loutfy M,MacGillivray J,Yudin MH,Campbell DM,Barozzino T,Baqi M,Read SE,Bitnun A

更新日期：2020-04-30 00:00:00

abstract：BACKGROUND:Previous studies of cerebrospinal fluid (CSF) shunt infection treatment have been limited in size and unable to compare patient and treatment characteristics by infecting organism. Our objective was to describe variation in patient and treatment characteristics for children with first CSF shunt infection, st...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Simon TD,Kronman MP,Whitlock KB,Browd SR,Holubkov R,Kestle JRW,Kulkarni AV,Langley M,Limbrick DD,Luerssen TG,Oakes J,Riva-Cambrin J,Rozzelle C,Shannon CN,Tamber M,Wellons Iii JC,Whitehead WE,Mayer-Hamblett N,Hydroceph

更新日期：2019-07-01 00:00:00

abstract：:Considerable progress has been made in the prevention, diagnosis, and management of pediatric patients with invasive fungal disease (IFD). The reported decreasing trend in the incidence of invasive candidiasis (IC) over the past 15 years in both neonates and children has been encouraging. Nevertheless, due to the grow...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Pana ZD,Roilides E,Warris A,Groll AH,Zaoutis T

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Egypt has the highest prevalence of hepatitis C virus (HCV) infection. Anti-HCV antibodies were detectable in 3% of children in Upper Egypt. Our aim was to evaluate the efficacy of ledipasvir/sofosbuvir for chronic HCV genotype 4 in adolescents with/without hematological disorders and to determine the effect...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Makhlouf NA,Abdelmalek MO,Ibrahim ME,Abu-Faddan NH,Kheila AE,Mahmoud AA

更新日期：2020-02-15 00:00:00

abstract：:Coronaviruses contribute to the burden of respiratory diseases in children, frequently manifesting in upper respiratory symptoms considered to be part of the "common cold." Recent epidemics of novel coronaviruses recognized in the 21st century have highlighted issues of zoonotic origins of transmissible respiratory vi...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Ogimi C,Kim YJ,Martin ET,Huh HJ,Chiu CH,Englund JA

更新日期：2020-04-30 00:00:00

abstract：Background:Pertussis is an important cause of hospitalization and death in infants too young to be vaccinated (aged <2 months). Limited data on infant pertussis have been reported from Central America. The aim of this study was to characterize acute respiratory illnesses (ARIs) attributable to Bordetella pertussis amon...

journal_title：Journal of the Pediatric Infectious Diseases Society

authors： Phadke VK,McCracken JP,Kriss JL,Lopez MR,Lindblade KA,Bryan JP,Garcia ME,Funes CE,Omer SB

更新日期：2018-12-03 00:00:00