99mTc-Radiolabeled TPGS Nanomicelles Outperform 99mTc-Sestamibi as Breast Cancer Imaging Agent.

abstract：:Multimodal nanoprobes are highly demanded for biomedical imaging applications to enhance the reliability of the diagnostic results. Among different types of nano-objects, ultrasmall silica gadolinium nanoparticle (SiGdNP) appears as a safe, effective, and versatile platform for this purpose. In this study, a new metho...

journal_title：Contrast media & molecular imaging

authors： Tran VL,Thakare V,Natuzzi M,Moreau M,Oudot A,Vrigneaud JM,Courteau A,Louis C,Roux S,Boschetti F,Denat F,Tillement O,Lux F

更新日期：2018-11-01 00:00:00

abstract：:An observational study was set up to assess the feasibility of [18F]FPRGD2 PET/CT for imaging patients with multiple myeloma (MM) and to compare its detection rate with low dose CT alone and combined [18F]NaF/[18F]FDG PET/CT images. Four patients (2 newly diagnosed patients and 2 with relapsed MM) were included and un...

journal_title：Contrast media & molecular imaging

authors： Withofs N,Cousin F,De Prijck B,Bonnet C,Hustinx R,Gambhir SS,Beguin Y,Caers J

更新日期：2017-07-27 00:00:00

abstract：Aim:To evaluate reproducibility and stability of radiomic features as effects of the use of different volume segmentation methods and reconstruction settings. The potential of radiomics in really capturing the presence of heterogeneous tumor uptake and irregular shape was also investigated. Materials and Methods:An an...

journal_title：Contrast media & molecular imaging

authors： Gallivanone F,Interlenghi M,D'Ambrosio D,Trifirò G,Castiglioni I

更新日期：2018-09-10 00:00:00

abstract：Purpose:Several meta-analyses have reported data about the diagnostic performance of positron emission tomography or positron emission tomography/computed tomography (PET or PET/CT) with different radiotracers in patients with suspicious lung cancer (LC) or pleural tumours (PT). This review article aims at providing an...

journal_title：Contrast media & molecular imaging

authors： Lococo F,Muoio B,Chiappetta M,Nachira D,Petracca Ciavarella L,Margaritora S,Treglia G

更新日期：2020-04-25 00:00:00

abstract：:Spectral molecular imaging is a new X-ray-based imaging technology providing highly specific 3D imaging at high spatial resolution that has the potential to measure disease activity and response to treatment noninvasively. The ability to identify and quantify components of tissue and biomarkers of disease activity der...

journal_title：Contrast media & molecular imaging

authors： Anderson NG,Butler AP

更新日期：2014-01-01 00:00:00

abstract：:We evaluated the difference in the status of dopamine transporters (DATs) depending on Parkinsonism, cerebellar, and autonomic features using F-18 FP-CIT positron emission tomography (PET) in multiple system atrophy with cerebellar ataxia (MSA-C). We also assessed whether the DAT PET could be useful in the management ...

journal_title：Contrast media & molecular imaging

authors： Jeong YJ,Cheon SM,Kang DY,Kim JW

更新日期：2017-11-29 00:00:00

abstract：Objective:We aimed to propose an automatic method based on Support Vector Machine (SVM) and Dynamic Contrast-Enhanced Magnetic Resonance Imaging (DCE-MRI) to segment the tumor lesions of head and neck cancer (HNC). Materials and Methods:120 DCE-MRI samples were collected. Five curve features and two principal componen...

journal_title：Contrast media & molecular imaging

authors： Deng W,Luo L,Lin X,Fang T,Liu D,Dan G,Chen H

更新日期：2017-09-07 00:00:00

abstract：:A new high-throughput MRI method for screening chemical exchange saturation transfer (CEST) agents is demonstrated, allowing simultaneous testing of multiple samples with minimal attention to sample configuration and shimming of the main magnetic field (B(0)). This approach, which is applicable to diamagnetic, paramag...

journal_title：Contrast media & molecular imaging

authors： Liu G,Gilad AA,Bulte JW,van Zijl PC,McMahon MT

更新日期：2010-05-01 00:00:00

abstract：:Various contrast agents (Magnevist, Gadovist and Multihance) loaded into polymeric nanocapsules were synthesized by the inverse miniemulsion technique. The relaxivity of the resultant contrast agents was assessed at 1.5 T magnetic field strength. The ionic relaxivity of the contrast agents could at least be maintained...

journal_title：Contrast media & molecular imaging

authors： Sharma S,Paiphansiri U,Hombach V,Mailänder V,Zimmermann O,Landfester K,Rasche V

更新日期：2010-03-01 00:00:00

abstract：:The development of molecular probes and novel imaging modalities, allowing better resolution and specificity, is associated with an increased potential for molecular imaging of atherosclerotic plaques especially in basic and pre-clinical research applications. In that context, a photoacoustic molecular probe based on ...

journal_title：Contrast media & molecular imaging

authors： Rouleau L,Berti R,Ng VW,Matteau-Pelletier C,Lam T,Saboural P,Kakkar AK,Lesage F,Rhéaume E,Tardif JC

更新日期：2013-01-01 00:00:00

abstract：:Developing agents with 'seek, treat and see' capability is critical for personalized molecular medicine. Those agents will specifically target the disease markers for diagnosis and apply the biologically effective dose for treatment. Retinoids regulate a multitude of biological processes. In addition, retinoic acid ca...

journal_title：Contrast media & molecular imaging

authors： Wang W,Qiu X,Zhang F,Sun J,Cameron AG,Wendt JA,Mawad ME,Ke S

更新日期：2011-07-01 00:00:00

abstract：:Various studies have shown that various cell types can be labeled with iron oxide particles and visualized by magnetic resonance imaging (MRI). However, reported protocols for cell labeling show a large variation in terms of labeling dose and incubation time. It is therefore not clear how different labeling protocols ...

journal_title：Contrast media & molecular imaging

authors： van Tiel ST,Wielopolski PA,Houston GC,Krestin GP,Bernsen MR

更新日期：2010-09-01 00:00:00

abstract：:Monodisperse mesoporous silica (mSiO(2) ) coated superparamagnetic iron oxide (Fe(3) O(4) @mSiO(2) ) nanoparticles (NPs) have been developed as a potential magnetic resonance imaging (MRI) T(2) contrast agent. To evaluate the effect of surface coating on MRI contrast efficiency, we examined the proton relaxivities of ...

journal_title：Contrast media & molecular imaging

authors： Ye F,Laurent S,Fornara A,Astolfi L,Qin J,Roch A,Martini A,Toprak MS,Muller RN,Muhammed M

更新日期：2012-09-01 00:00:00

abstract：:Self-aggregation of dyes even at low concentrations poses a considerable challenge in preparing sufficiently bright molecular probes for in vivo imaging, particularly in the conjugation of near infrared cyanine dyes to polypeptides with multiple labeling sites. Such self-aggregation leads to a significant energy trans...

journal_title：Contrast media & molecular imaging

authors： Zhegalova NG,He S,Zhou H,Kim DM,Berezin MY

更新日期：2014-09-01 00:00:00

abstract：:Advances in regenerative medicine are rapidly transforming healthcare. A cornerstone of regenerative medicine is the introduction of cells that were grown or manipulated in vitro. Key questions that arise after these cells are re-introduced are: whether these cells are localized in the appropriate site; whether cells ...

journal_title：Contrast media & molecular imaging

authors： Modo M,Kolosnjaj-Tabi J,Nicholls F,Ling W,Wilhelm C,Debarge O,Gazeau F,Clement O

更新日期：2013-11-01 00:00:00

abstract：:Magnetic fluid hyperthermia (MFH) with chemically synthesized nanoparticles is currently used in clinical trials as it destroys tumor cells with an extremely localized deposition of thermal energy. In this paper, we investigated an MFH protocol based on magnetic nanoparticles naturally produced by magnetotactic bacter...

journal_title：Contrast media & molecular imaging

authors： Mannucci S,Tambalo S,Conti G,Ghin L,Milanese A,Carboncino A,Nicolato E,Marinozzi MR,Benati D,Bassi R,Marzola P,Sbarbati A

更新日期：2018-07-11 00:00:00

abstract：Objective:To qualitatively and quantitatively compare the contrast-enhanced magnetic resonance angiography (MRA) and magnetic resonance imaging (MRI) in one-stop shop of abdominal imaging with Gadobutrol and Gd-DTPA at equimolar doses of gadolinium. Materials and Methods:This was a prospective designed, multiple cente...

journal_title：Contrast media & molecular imaging

authors： Liu X,Li Z,Zhang W,Yang C,Diao Y,Duan T,Fu Y,Ren J,Bin S

更新日期：2019-12-02 00:00:00

abstract：:Purpose. To investigate the value of SUV metrics and radiomic features based on the ability of 18F-FDG PET/CT in differentiating between breast lymphoma and breast carcinoma. Methods. A total of 67 breast nodules from 44 patients who underwent 18F-FDG PET/CT pretreatment were retrospectively analyzed. Radiomic paramet...

journal_title：Contrast media & molecular imaging

authors： Ou X,Wang J,Zhou R,Zhu S,Pang F,Zhou Y,Tian R,Ma X

更新日期：2019-02-25 00:00:00

abstract：:Overexpression of the chemokine-4 receptor (CXCR4) in brain tumors is associated with high cancer cell invasiveness. Recently, we reported the preclinical evaluation of 99mTc-CXCR4-L (cyclo-D-Tyr-D-[NMe]Orn[EDDA-99mTc-6-hydrazinylnicotinyl]-Arg-NaI-Gly) as a SPECT radioligand capable of specifically detecting the CXCR...

journal_title：Contrast media & molecular imaging

authors： Vallejo-Armenta P,Santos-Cuevas C,Soto-Andonaegui J,Villanueva-Pérez RM,González-Díaz JI,García-Pérez FO,Arrellano-Zarate A,Luna-Gutiérrez M,Azorín-Vega E,Ocampo-García B,Ferro-Flores G

更新日期：2020-04-27 00:00:00

abstract：:The aim of this work was to investigate the MRI findings on tumor xenografts induced in nude mice by the inoculation of human pancreatic cancer cells labeled with superparamagnetic iron oxide (SPIO), and to monitor the kinetics of SPIO distribution in tumor xenografts. The labeled cancer cells were subcutaneously inoc...

journal_title：Contrast media & molecular imaging

authors： Wu CY,Pu Y,Liu G,Shao Y,Ma QS,Zhang XM

更新日期：2012-01-01 00:00:00

abstract：:Optical fluorescence imaging has been developed as an aid to intraoperative diagnosis to improve surgical and endoscopic procedures. Compared with other intraoperative imaging methods, it is lower in cost, has a high safety margin, is portable and easy to use. γ-glutamyl hydroxymethyl rhodamine green (gGlu-HMRG) is a ...

journal_title：Contrast media & molecular imaging

authors： Harada T,Nakamura Y,Sato K,Nagaya T,Choyke PL,Seto Y,Kobayashi H

更新日期：2016-11-01 00:00:00

abstract：:The purpose was to investigate whether MnCl(2) can serve as an MRI contrast agent to detect chronic cryoinjury infarction in pigs in vivo and whether MnCl(2) causes significant hemodynamic disturbances. Hearts were subjected to a topical 2 min cryothermia to establish myocardial infarction (MI). Thereafter GdDTPA-enha...

journal_title：Contrast media & molecular imaging

authors： Yang Y,de Gervai PD,Sun J,Gruwel ML,Kupriyanov V

更新日期：2011-11-01 00:00:00

abstract：:Glioblastoma multiforme is the most aggressive form of brain tumor. Early and accurate diagnosis of glioma and its borders is an important step for its successful treatment. One of the promising targets for selective visualization of glioma and its margins is connexin 43 (Cx43), which is highly expressed in reactive a...

journal_title：Contrast media & molecular imaging

authors： Abakumova T,Abakumov M,Shein S,Chelushkin P,Bychkov D,Mukhin V,Yusubalieva G,Grinenko N,Kabanov A,Nukolova N,Chekhonin V

更新日期：2016-01-01 00:00:00

abstract：:Physicians and scientists use a broad spectrum of terms to classify contrast media (CM)-induced adverse reactions. In particular, the designation of hypersensitivity reactions is quite varied. Consequently, comparisons of different papers dealing with this subject are difficult or even impossible. Moreover, general de...

journal_title：Contrast media & molecular imaging

authors： Böhm I,Heverhagen JT,Klose KJ

更新日期：2012-11-01 00:00:00

abstract：Background:To evaluate the clinical and prognostic value of PET/CT with combination of 68Ga-DOTATATE and 18F-FDG in gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs). Method:83 patients of GEP-NENs who underwent 68Ga-DOTATATE and 18F-FDG PET/CT were enrolled between June 2013 and December 2016. Well-different...

journal_title：Contrast media & molecular imaging

authors： Zhang P,Yu J,Li J,Shen L,Li N,Zhu H,Zhai S,Zhang Y,Yang Z,Lu M

更新日期：2018-02-26 00:00:00

abstract：:Barium sulfate and lead oxide contrast media are frequently used for cadaver-based angiography studies. These contrast media have not previously been compared to determine which is optimal for the visualisation and measurement of blood vessels. In this study, the lower limb vessels of 16 embalmed Wistar rats, and four...

journal_title：Contrast media & molecular imaging

authors： Kingston MJ,Perriman DM,Neeman T,Smith PN,Webb AL

更新日期：2016-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:The purpose of this pilot study was to establish the ability of dynamic contrast enhanced computed tomography (DCE-CT) to detect changes in tumor blood flow (BF) and oxygenation induced by vasoactive substances in rats. MATERIALS AND METHODS:Under ultrasound guidance, a fiber-optic probe was g...

journal_title：Contrast media & molecular imaging

authors： Pollard RE,Larson RF

更新日期：2011-01-01 00:00:00

abstract：:Sialic acid-binding immunoglobulin-like lectin 9 (Siglec-9) is a ligand of inflammation-inducible vascular adhesion protein-1 (VAP-1). We compared 68Ga-DOTA- and 18F-fluorodeoxyribose- (FDR-) labeled Siglec-9 motif peptides for PET imaging of inflammation. Methods. Firstly, we examined 68Ga-DOTA-Siglec-9 and 18F-FDR-S...

journal_title：Contrast media & molecular imaging

authors： Virtanen H,Silvola JMU,Autio A,Li XG,Liljenbäck H,Hellberg S,Siitonen R,Ståhle M,Käkelä M,Airaksinen AJ,Helariutta K,Tolvanen T,Veres TZ,Saraste A,Knuuti J,Jalkanen S,Roivainen A

更新日期：2017-12-31 00:00:00

abstract：:Chemical exchange saturation transfer (CEST) imaging is an emerging MRI technique relying on the use of endogenous or exogenous molecules containing exchangeable proton pools. The heterogeneity of the water resonance frequency offset plays a key role in the occurrence of artifacts in CEST-MR images. To limit this draw...

journal_title：Contrast media & molecular imaging

authors： Stancanello J,Terreno E,Castelli DD,Cabella C,Uggeri F,Aime S

更新日期：2008-07-01 00:00:00

abstract：:Melanoma is the most dangerous form of skin cancer and its incidence is rising each year. Because the current methods of diagnosis based on the visual aspect of the tumor show limitations, several new techniques are emerging to help in this diagnosis, amongst which are magnetic resonance imaging (MRI) and electron par...

journal_title：Contrast media & molecular imaging

authors： Godechal Q,Mignion L,Karroum O,Magat J,Danhier P,Morandini R,Ghanem GE,Leveque P,Gallez B

更新日期：2014-03-01 00:00:00