Prognostic value of coronary artery disease-reporting and data system (CAD-RADS) score for cardiovascular events in ischemic stroke.

abstract：:Cytosolic Phospholipase A(2) (cPLA(2)) has been implicated in receptor-mediated release of arachidonic acid from membrane phospholipids, the limiting step in prostacyclin and other eicosanoid production. Its activity is controlled by Ca(++) levels and enzymatically regulated phosphorylation. The purpose of this study ...

journal_title：Atherosclerosis

authors： Gudmundsdóttir IJ,Halldórsson H,Magnúsdóttir K,Thorgeirsson G

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Exercise training (ET) helps treat atherosclerosis. However, many patients stop regular ET for various reasons. The effect of detraining on atherosclerosis is not well studied. We examined the effects of ET vs. short-term detraining on atheromatous matrix-metalloproteinase (MMP) activity in preexist...

journal_title：Atherosclerosis

authors： Kim J,Jang HJ,Schellingerhout D,Kang JW,Choi S,Oh H,Kim EJ,Lee SK,Lee JS,Kwon IC,Kim K,Koh YJ,Ryu WS,Kim DE

更新日期：2020-04-01 00:00:00

abstract：:VPS10P domain receptors are a unique class of sorting receptors that direct intracellular transport of target proteins in neurons and that play central roles in neurodegenerative processes. Surprisingly, genome-wide association studies now implicate the very same receptors in cardiovascular and metabolic disturbances....

journal_title：Atherosclerosis

authors： Schmidt V,Willnow TE

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Risk factors of cardiovascular disease such as lipid aberrations, hypertension, abdominal adiposity and elevations in systemic inflammation, are prominent aetiologies in hyperlipidemia. Supplementation with n-3 PUFA is associated with a reduction in cardiovascular events through its hypotriglyceridemic, anti...

journal_title：Atherosclerosis

authors： Micallef MA,Garg ML

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Whether carotid atherosclerosis is associated with an increased risk for ischemic stroke in patients with atrial fibrillation (AF) on anticoagulant treatment is undefined. To explore this association, patients with AF on treatment with vitamin K antagonists were included in a multicenter, prospectiv...

journal_title：Atherosclerosis

authors： Becattini C,Dentali F,Camporese G,Sembolini A,Rancan E,Tonello C,Manina G,Padayattil S,Agnelli G

更新日期：2018-04-01 00:00:00

abstract：:Serum high density lipoprotein cholesterol (HDL-C), total cholesterol (TC) and triglycerides (TG) were determined, and values of low density lipoprotein cholesterol (LDL-C), HDL-C/TC (%), and the LDL-C/HDL-C (ratio) were calculated in 1101 healthy Chinese men and women, 77 patients with coronary heart disease (CHD), 7...

journal_title：Atherosclerosis

authors： Cai HJ,Li ZX,Yang SM

更新日期：1982-06-01 00:00:00

abstract：:Previous studies have shown that the A to G transition occurring at position -75 bp upstream of the transcriptional start site in the human apolipoprotein A-I gene may affect plasma high density lipoprotein cholesterol (HDL-C) levels and low density lipoprotein cholesterol (LDL-C) response to changes in amount of diet...

journal_title：Atherosclerosis

authors： Mata P,Lopez-Miranda J,Pocovi M,Alonso R,Lahoz C,Marin C,Garces C,Cenarro A,Perez-Jimenez F,de Oya M,Ordovas JM

更新日期：1998-04-01 00:00:00

abstract：OBJECTIVE:Significant sex differences exist in cardiovascular diseases. Although an impact of gonadal hormones is presumed, it is largely unknown whether sexually dimorphic gene expression also plays a role and whether cells themselves show intrinsic sex differences. METHODS:We performed whole genome expression analys...

journal_title：Atherosclerosis

authors： Lorenz M,Koschate J,Kaufmann K,Kreye C,Mertens M,Kuebler WM,Baumann G,Gossing G,Marki A,Zakrzewicz A,Miéville C,Benn A,Horbelt D,Wratil PR,Stangl K,Stangl V

更新日期：2015-05-01 00:00:00

abstract：:The detailed distribution of atherosclerotic lesions in the branching region of the left main coronary artery in man was studied. Tissue cubes of the hearts, containing the left coronary arteries, were removed, and 1.5-mm-thick parallel and consecutive slices were cut perpendicular to the main coronary artery. Histolo...

journal_title：Atherosclerosis

authors： Grøttum P,Svindland A,Walløe L

更新日期：1983-04-01 00:00:00

abstract：OBJECTIVE:C-reactive protein (CRP) gene variation, in particular an rs2794521 variant was recently associated with type 2 diabetes mellitus (T2DM) in Pima Indians. RESEARCH DESIGN AND METHODS:The present investigation was conducted to replicate this previous association, and to further examine the potential associatio...

journal_title：Atherosclerosis

authors： Zee RY,Germer S,Thomas A,Raji A,Rhees B,Ridker PM,Lindpaintner K,Williams GH,Nathan DM,Martin M

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:CD36 signal transductions have been reported by a variety of lipid moiety of oxidized low-density lipoprotein (oxLDL), however, CD36 signal induced by 7-ketocholesteryl-9-carboxynonanoate (oxLig-1), a lipid moiety of oxLDL has not been elucidated. METHODS AND RESULTS:OxLig-1 leads to activation and recruitm...

journal_title：Atherosclerosis

authors： Li W,Wang D,Chi Y,Wang R,Zhang F,Ma G,Chen Z,Li J,Liu Z,Matsuura E,Liu Q

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:Currently no data exists regarding the outcomes after the novel endothelial progenitor cell capturing stent (EPCcS) placement in bifurcation lesions using a provisional T-stenting. This study evaluates the 1-year clinical outcome in patients treated with the EPCcS for a bifurcation lesion using a provisional ...

journal_title：Atherosclerosis

authors： Beijk MA,Klomp M,Koch KT,Henriques JP,Vis MM,Baan J Jr,Tijssen JG,Piek JJ,de Winter RJ

更新日期：2010-12-01 00:00:00

abstract：:Atherosclerosis is a major underlying cause of ischemic heart diseases, ischemic stroke, and peripheral artery disease. Atherosclerotic plaque progression is characterized by chronic progressive inflammation of the arterial wall, endothelial cell dysfunction, and subendothelial lipoprotein retention. Incretin drugs, g...

journal_title：Atherosclerosis

authors： Gallego-Colon E,Wojakowski W,Francuz T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Micro-particles (MP) are secreted by various cells. Their biological roles in health and in disease remain unknown. Here we describe formation of MP in the process of ABCA1-dependent cholesterol efflux in different cell types. METHODS:The ATP-binding cassette transporter, subfamily A, member 1 (ABC...

journal_title：Atherosclerosis

authors： Hafiane A,Genest J

更新日期：2017-02-01 00:00:00

abstract：:Numerous epidemiological studies have shown that lipoprotein(a) (Lp(a)) is an independent risk factor for the premature development of cardiovascular disease. In spite of such evidence, the structural and functional features of this atherogenic, cholesterol-rich particle are not clearly understood. We have demonstrate...

journal_title：Atherosclerosis

authors： Huby T,Chapman J,Thillet J

更新日期：1997-08-01 00:00:00

abstract：:Investigations to date have demonstrated that the underlying etiology, causes and burden of stroke may be different for women and men. However, data regarding sex differences among young cerebral ischemic stroke patients remains scarce. We conducted this study in 669 young Chinese adults with acute ischemic stroke as ...

journal_title：Atherosclerosis

authors： Zhang B,Pu S,Zhang W,Yang N,Shen G,Yin J,Yi Y,Gao Q,Gao C

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Studying atherosclerotic calcification in vivo requires mouse models with genetic modifications. Previous studies showed that injection of recombinant adeno-associated virus vector (AAV) encoding a gain-of-function mutant PCSK9 into mice promotes atherosclerosis. We aimed to study cardiovascular cal...

journal_title：Atherosclerosis

authors： Goettsch C,Hutcheson JD,Hagita S,Rogers MA,Creager MD,Pham T,Choi J,Mlynarchik AK,Pieper B,Kjolby M,Aikawa M,Aikawa E

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:Sulforaphane, a naturally occurring organosulfur compound in broccoli, has chemopreventive properties in cancer. However, the effects of sulforaphane in vascular diseases have not been examined. We therefore aimed to investigate the effects of sulforaphane on vascular smooth muscle cell (VSMC) proliferation a...

journal_title：Atherosclerosis

authors： Kwon JS,Joung H,Kim YS,Shim YS,Ahn Y,Jeong MH,Kee HJ

更新日期：2012-11-01 00:00:00

abstract：:The change of acid cholesteryl ester hydrolase activity in mononuclear leukocyte following treatment of diabetes mellitus was studied in 21 patients with non-insulin-dependent diabetes mellitus (NIDDM). Enzyme activity before treatment in the patients was significantly lower than that in 14 age-matched healthy subject...

journal_title：Atherosclerosis

authors： Onuma T,Tsutsui M,Boku A,Yanada A,Ochiai S,Takebe K

更新日期：1992-02-01 00:00:00

abstract：:We have used DNA and protein polymorphisms for the third complement component (C3) to assess the potential of DNA markers in the diagnosis and study of familial hypercholesterolaemia (FH), and to confirm the reported linkage between FH and C3. The inheritance of FH and the C3 gene has been studied in 10 families by co...

journal_title：Atherosclerosis

authors： Humphries SE,Donald JA,McFadden JJ,Shull S,Williamson R,Jowett NI,Galton DJ,Julsrud JO,Berg K,Heiberg A

更新日期：1984-09-01 00:00:00

abstract：:Cholesterol lowering in both primary and secondary prevention has been clearly demonstrated to lower coronary morbidity and, in secondary prevention, to lower coronary mortality as well. Putative dangers of cholesterol lowering remain unproven. Population studies linking low cholesterol to noncoronary mortalities do n...

journal_title：Atherosclerosis

authors： LaRosa JC

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:Serum C-reactive protein (CRP) is a strong risk predictor of cardiovascular events, and tissue factor (TF) plays a central role in thrombus formation of advanced atherosclerotic plaques. Aim of the present study was to quantify in situ CRP and TF in coronary atherectomy specimens associated with acute corona...

journal_title：Atherosclerosis

authors： Andrié RP,Bauriedel G,Braun P,Höpp HW,Nickenig G,Skowasch D

更新日期：2009-01-01 00:00:00

abstract：:Monocytes and macrophages synthesize tissue factor (TF) which plays a role in thrombogenicity in coronary artery disease. This study was conducted to investigate the effect of Rho/Rho-kinase inhibition on the synthesis of TF in cultured human monocytes. 3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibit...

journal_title：Atherosclerosis

authors： Nagata K,Ishibashi T,Sakamoto T,Ohkawara H,Shindo J,Yokoyama K,Sugimoto K,Sakurada S,Takuwa Y,Nakamura S,Teramoto T,Maruyama Y

更新日期：2002-07-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of pioglitazone on endothelial and adipose tissue dysfunction in newly detected IGT patients with CAD. METHODS AND DESIGN:Participants (n=25) were randomized to treatment with either placebo or pioglitazone (30 mg/day) for 12 weeks. Before and after treatment we evaluated endothelia...

journal_title：Atherosclerosis

authors： Rizza S,Cardellini M,Porzio O,Pecchioli C,Savo A,Cardolini I,Senese N,Lauro D,Sbraccia P,Lauro R,Federici M

更新日期：2011-03-01 00:00:00

abstract：:The effects of the artificial triglyceride-phospholipid emulsion (10% intralipid) on HDL subfraction were studied in vivo. After a 14-h fast, subjects received intralipid via a 4-h infusion. Serum lipoproteins were analyzed before and at 4 and 6 h after the start of the infusion. At 4-h the following acute changes by ...

journal_title：Atherosclerosis

authors： Sakuma N,Lin C,Matsumoto Y,Ikeuchi R,Ichikawa T,Hirata H,Noguchi Y,Fujinami T

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Atherosclerosis develops with age and is partially controlled by genetics. Research to date has identified common variants with small effects on atherosclerosis related traits. We aimed to use family-based genome-wide linkage analysis to identify chromosomal regions potentially harboring rare varian...

journal_title：Atherosclerosis

authors： Kuipers AL,Wojczynski MK,Barinas-Mitchell E,Minster RL,Wang L,Feitosa MF,Kulminski A,Thyagarajan B,Lee JH,Province MA,Newman AB,Zmuda JM,Long-Life Family Study.

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Moderate red wine has been shown to reduce cardiovascular disease (CVD) risk, however the effects on certain CVD risk factors are unclear. In this study we have investigated the effects of dealcoholised red wine (DRW) and full-complement red wine (RW) on several cardiovascular risk factors in mildly hypercho...

journal_title：Atherosclerosis

authors： Naissides M,Mamo JC,James AP,Pal S

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:Vasa vasorum (VV) have been implicated to play a role in the pathogenesis of atherosclerosis. This study was designed to describe the distribution of VV density in different vascular beds in humans and to investigate the association between VV density and the known distribution of atherosclerosis in human art...

journal_title：Atherosclerosis

authors： Hildebrandt HA,Gossl M,Mannheim D,Versari D,Herrmann J,Spendlove D,Bajanowski T,Malyar NM,Erbel R,Lerman LO,Lerman A

更新日期：2008-07-01 00:00:00

abstract：:The cell-adhesion molecule CD44 likely participates in atherosclerosis development. We have shown previously that pro-inflammatory cytokines affect CD44 expression. Therefore, this work examined the role of elevated CD44 levels in human macrophages. Macrophages from human atherosclerotic subjects (n=15) showed elevate...

journal_title：Atherosclerosis

authors： Hägg D,Sjöberg S,Hultén LM,Fagerberg B,Wiklund O,Rosengren A,Carlsson LM,Borén J,Svensson PA,Krettek A

更新日期：2007-02-01 00:00:00

abstract：:In previous works, it has been evidenced that lipoperoxidative injury to macrophages caused by oxidatively modified low-density lipoprotein (O-LDL) plays an important role in foam cell formation, and that PSK, a protein bound polysaccharide extracted from the class Basidiomycetes Coriolus Versicolor, can protect macro...

journal_title：Atherosclerosis

authors： Yuan C,Mei Z,Liu S,Yi L

更新日期：1996-08-02 00:00:00