Neuropathic pain in ankylosing spondylitis: a meta-analysis.

Abstract:

AIM:The aim of this study was to compare demographic characteristics, disease activity, functional status, and quality of life between ankylosing spondylitis (AS) with neuropatic pain (NP) and AS without NP (Non-NP). METHODS:The MEDLINE via PubMed, Cochrane, Scopus, and Embase database, from the earliest available date of indexing through December 20, 2018, were searched for comparative studies evaluating NP in AS patients. Two authors performed the data extraction independently. Any discrepancies were resolved by consensus. RESULTS:Four comparative studies were identified. There was no statistically significant difference in terms of age, body mass index, symptom duration, and inflammatory markers, such as erythrocyte sedimentation rate and C‑reactive protein between NP and Non-NP. The sex ratios (F/M) were approximately 1/1 in NP and 1/2 in Non-NP and the proportion of human leukocyte antigen (HLA) B27-positive patients in NP and Non-NP was 65.7% and 83.0%, respectively. NP patients had significantly higher visual analogue scale pain scores, higher Bath Ankylosing Spondylitis Disease Activity Index, higher Bath Ankylosing Spondylitis Functional Index, and lower SF-Item Short Form physical component scores compare to Non-NP patients. CONCLUSION:The current meta-analysis showed that NP patients had significantly higher pain severity, higher disease activity and lower quality of life than Non-NP patients. The sex ratio (F/M) and proportion of HLA-B27 positive patients were different between the two groups. Further well-designed studies are needed to substantiate our results.

journal_name

Z Rheumatol

authors

Kim TW,Son SM,Lee JS

doi

10.1007/s00393-019-0654-3

subject

Has Abstract

pub_date

2020-02-01 00:00:00

pages

95-102

issue

1

eissn

0340-1855

issn

1435-1250

pii

10.1007/s00393-019-0654-3

journal_volume

79

pub_type

杂志文章,meta分析
  • [Bone morphogenetic proteins in the skeletal system].

    abstract::Bone morphogenetic proteins (BMPs) belong to the transforming growth factor-beta superfamily. Their potential for organ and tissue regeneration and repair has been intensively investigated in recent years. Studies on fetal development have demonstrated the important role of these proteins for the development and diffe...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s00393-005-0665-0

    authors: Bramlage CP,Häupl T,Kaps C,Bramlage P,Müller GA,Strutz F

    更新日期:2005-09-01 00:00:00

  • [Essential cryoglobulinemic vasculitis with severe peripheral neuropathy and neurogenic muscular atrophy -- inducing remission by cascade filtration].

    abstract::We report on a 60 year old patient with peripheral neuropathy, neurogenic muscular atrophy, skin ulcers, arthritis and weakness. Detection of cryoglobulins in association with typical clinical symptoms, exclusion of hepatitis C and any other disease led to a rare diagnosis: essential cryoglobulinemic vasculitis. The c...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-002-0389-3

    authors: Strunk J,Taborski U,Neeck G

    更新日期:2002-12-01 00:00:00

  • [The status of Churg-Strauss syndrome among other hypereosinophilic, granulomatous and vasculitic diseases].

    abstract::The Churg-Strauss syndrome is a disorder characterized by hypereosinophilia and systemic vasculitis occurring in patients with asthma and allergic rhinitis. Only few patients are identified as having this syndrome. The three histological criteria are necrotizing vasculitis, tissue infiltration by eosinophils, and extr...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Stockmann G

    更新日期:1988-11-01 00:00:00

  • [Treatment of systemic sclerosis].

    abstract::Systemic sclerosis (SSc, scleroderma) is a multisystem disease with a bad prognosis. No drugs have been shown to cure this disease. In view of its pathogenesis, in which immune responses are presumed to play an important role, immune suppressive therapies are widely applied in the treatment of SSc. Recent placebo-cont...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s00393-006-0075-y

    authors: van den Hoogen FH

    更新日期:2006-07-01 00:00:00

  • [Acetylcholine receptor antibody in D-penicillamine therapy].

    abstract::Since 1978 a 63-year-old woman with rheumatoid arthritis received D-penicillamine (D-PA) in a daily dose of 250-500 mg (mean 300 mg/d). In 1982 the patient complained of diplopia for several days, the ophthalmological and neurological examinations three days later were normal. In July 1983 she developed a myasthenic s...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Kolarz G,Maida EM

    更新日期:1986-05-01 00:00:00

  • [Follow-up studies after bicondylar superficial replacement of rheumatoid knee joint destruction].

    abstract::This study documents prospectively the Knee Society knee- and function score of 28 patients with rheumatoid arthritis with 34 PFC unconstrained total knee arthroplasties from preoperative values on at yearly intervals. The average follow-up period was 3.4 years (range 2-5.5 y). At last follow-up over 80% of the knees ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s003930050035

    authors: König A,Janssen E,Scheidler M,Gohlke F

    更新日期:1997-07-01 00:00:00

  • [Pulmonary manifestations of lupus erythematodes visceralis].

    abstract::Eight patients with SLE were found on clinical and roentgenological grounds or by respiratory function tests to have evidence of lung involvement. Great discrepancies were noted between clinical findings and the results of the respiratory function tests on the one hand and lacking or discrete radiological changes on t...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Görlitz N,Berzon R,Rössner B,Wessel G,Jäckel R

    更新日期:1976-03-01 00:00:00

  • [Systemic sclerosis-clinical picture, diagnosis, and treatment].

    abstract::Systemic sclerosis is a rare rheumatologic disease that is characterised by skin and organ fibrosis as well as vascular changes and the occurrence of specific autoantibodies. It has a high morbidity and mortality while its manifestations show significant heterogeneity in patients. Thus, diagnosis and follow-up of pati...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-019-0639-2

    authors: Becker MO,Distler O,Maurer B

    更新日期:2019-06-01 00:00:00

  • [Lifelong heavy agricultural work and development of arthrosis of the hand--a case study].

    abstract::Heavy physical work load is a known determinant of osteoarthritis of the hip, which may account for the high risk observed among farmers. On the other hand, the data on influence of heavy manual work in the pathogenesis of hand osteoarthritis are still controversial. We examined 25 retired farm laborers who strenuousl...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s003930050193

    authors: Schmid L,Dreier D,Muff B,Allgayer B,Schlumpf U

    更新日期:1999-12-01 00:00:00

  • [Evidence-based treatment recommendations for familial Mediterranean fever : A joint statement by the Society for Pediatric and Adolescent Rheumatology and the German Society for Rheumatology].

    abstract:BACKGROUND:Familial Mediterranean fever (FMF) in Germany is a rare, genetically linked disease of childhood and adolescence, which is characterized by recurrent febrile episodes and clinical signs of peritonitis, pleuritis and arthritis. Treatment with colchicine is effective and well-tolerated in the majority of patie...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s00393-018-0588-1

    authors: Kallinich T,Blank N,Braun T,Feist E,Kiltz U,Neudorf U,Oommen PT,Weseloh C,Wittkowski H,Braun J

    更新日期:2019-02-01 00:00:00

  • [German patient version of the ASAS/EULAR recommendations for the management of ankylosing spondylitis].

    abstract::The evidence-based recommendations on the management of ankylosing spondylitis (AS) have enjoyed a high level of acceptance and circulation in Germany, as well as in other European countries. To make patient participation in the decision-making process regarding their disease easier, as well as to strengthen the physi...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-009-0428-4

    authors: Kiltz U,Feldtkeller E,Braun J

    更新日期:2010-03-01 00:00:00

  • Chondroneutrality of meloxicam in rats with spontaneous osteoarthrosis of the ankle joint.

    abstract::The effect of meloxicam, a new non-steroidal anti-inflammatory drug, on spontaneous osteoarthrosis of the ankle joint in Crl: CDBR rats was investigated. The drug was administered in the feed at doses of 0.4, 0.6 and 0.8 mg/kg/day over a period of 2 years to 50 males and 50 females per dose. 100 male rats and 100 fema...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s003930050017

    authors: Mohr W,Lehmann H,Engelhardt G

    更新日期:1997-01-01 00:00:00

  • Enumeration of T cell subsets and functional suppressor cell assays in patients with rheumatoid arthritis and HLA-B27-associated arthritis.

    abstract::Seronegative rheumatoid arthritis (RA) patients have increased proportions of OKT-4+ (helper) T cells and diminished proportions of OKT-8+ (suppressor/cytotoxic) T cells in the peripheral blood. This phenomenon corresponds to diminished inhibition of B cell activation by peripheral blood lymphocytes (PBL). Seropositiv...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Lemm G,Warnatz H

    更新日期:1984-05-01 00:00:00

  • Serum sulfhydryl groups in rheumatoid arthritis.

    abstract::The sulfhydryl groups are chemically active parts of the protein molecule and participate in many important biochemical and metabolic processes. The present material comprised 132 patients with rheumatoid arthritis, 104 patients with other diseases and 44 controls. The patients with rheumatoid arthritis had decreased ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Haataja M,Kalliomäki JL

    更新日期:1977-03-01 00:00:00

  • [Ophthalmological diagnosis in systemic vasculitis].

    abstract::Ocular manifestations of systemic vasculitides are extraordinarily pleomorph and have been described for many decades. In the introduction the special interaction of the immune system and the eye is outlined. Thereafter diagnostic procedures of patients suffering from systemic vasculitides are shown from an ophthalmol...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s003930170048

    authors: Nölle B

    更新日期:2001-08-01 00:00:00

  • [The knee joint in rheumatoid arthritis-current orthopaedic surgical treatment options].

    abstract::The knee joint is often involved in rheumatoid arthritis. Despite ever-improving medical antirheumatic therapies, surgical treatment continues to play an important role in optimal multidisciplinary care. The aim of the present work is to process current orthopedic surgical therapy procedures on the knee joint accordin...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s00393-018-0534-2

    authors: Maderbacher G,Greimel F,Schaumburger J,Grifka J,Baier C

    更新日期:2018-12-01 00:00:00

  • [Systemic sclerosis - diagnosis and classification].

    abstract::Systemic sclerosis (SSc) is a polymorphic and heterogenic systemic disorder with inflammation, fibrosis and vascular damage. Early diagnosis and classification may be difficult if disease expression is oligosymptomatic (undifferentiated), presenting with only Raynaud's phenomenon or limited scleroderma. Scleroderma sp...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s00393-006-0065-0

    authors: Genth E,Krieg T

    更新日期:2006-07-01 00:00:00

  • [Possibilities and limits of daily coping with illness by patients with chronic polyarthritis].

    abstract::A central problem of persons with chronic polyarthritis is the necessary adaptation to deteriorating health in everyday activities. Difficulties and burdens of this adaptation are parts of the study undertaken in the Unna Model, which was part of the research on "Local Services for CP-Patients". In the first part two ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Grunow-Lutter V,Grunow D

    更新日期:1992-01-01 00:00:00

  • [Periprosthetic infections in systemic inflammatory rheumatic disease. Review article on diagnostics and therapy].

    abstract:BACKGROUND:Patients with an inflammatory disease have an elevated risk for periprosthetic joint infections due to impairment of the immune system caused by the disease itself in combination with disease-modifying antirheumatic drugs (DMARD). These infections can cause life-threatening sepsis. Unfortunately recommendati...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s00393-013-1346-z

    authors: Illgner U,Uekötter A,Bause L

    更新日期:2014-06-01 00:00:00

  • [Current status and perspectives of ambulatory rheumatologic health care in Germany : economic structural conditions and motivation of rheumatologists].

    abstract:AIM:To gather information about current structures in rheumatologic ambulatory health care in Germany. Based on the results recommendations on future structures will be evaluated. METHODS:Data collection and statistical analysis via a structured 10-page questionnaire answered by members of the German Association of Rh...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-007-0190-4

    authors: Mittendorf T,Edelmann E,Kekow J,von Hinüber U,Müller-Brodmann W,Graf von der Schulenburg JM

    更新日期:2007-11-01 00:00:00

  • [Role of plasmapheresis and immunoadsorption in salvage therapy of rheumatological diseases].

    abstract::Many rheumatological diseases are either caused by specific known proteins, such as antibodies or mediated by a plethora of cytokines. Both the unspecific immunosuppressive therapy and the specific action of biologics usually require time to be effective; therefore, extracorporeal forms of treatment are increasingly b...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s00393-016-0219-7

    authors: Boser M,Kielstein JT

    更新日期:2016-12-01 00:00:00

  • [The enterprising Irishman Bernard Connor (1666-1698)].

    abstract::In the thesis of the Irish physician Bernard Connor (1666-1698) from 1693 in Rheims he describes the torso of a man whose bones were joined together due to ankylosing spondylitis which is considered to be the first example of such skeletal findings. This communication must however be seen in connection with earlier an...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 传,历史文章,杂志文章

    doi:10.1007/s00393-010-0657-6

    authors: Keitel W

    更新日期:2012-06-01 00:00:00

  • [Significance of interleukin 1 and related monokines in the pathogenesis of chronic polyarthritis].

    abstract::Activated monocytes/macrophages secrete monokines, regulatory proteins which are capable of initiating and maintaining immune processes as well as having an effect on other non immunocompetent cells. In rheumatoid arthritis the monokine Interleukin-1 (IL-1) was detected in the synovial fluid. IL-1 activates immunocomp...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Hermann E,Müller W

    更新日期:1985-09-01 00:00:00

  • [Epidemiology and patient management in the area of spondyloarthritis].

    abstract::Within the group of inflammatory rheumatic diseases, spondyloarthropathy is the most common diagnosis after rheumatoid arthritis. Its prevalence was long underestimated. Ankylosing spondylitis (AS) and undifferentiated spondyloathropathy (uSpA) are the most common subgroups in western countries. There are still diffic...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章,评审

    doi:10.1007/s003930200004

    authors: Haibel H,Rudwaleit M,Braun J,Sieper J

    更新日期:2002-02-01 00:00:00

  • [Diagnostic and prognostic significance of serologic studies in Yersinia arthritis].

    abstract::Commonly-used serological methods for the determination of Yersinia antibodies are based on the presence of agglutinins, which are frequently absent or of low titer when arthritis begins. Stool cultures are usually negative at that time, so many Yersinia infections are underdiagnosed. On the other hand, significant ag...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Grasedyck K,Heesemann J

    更新日期:1987-07-01 00:00:00

  • [Scleromyxedema. A chronic progressive systemic disease].

    abstract:BACKGROUND:Scleromyxedema is a rare connective tissue disease that may affect numerous internal organs in addition to the skin. The disease is almost exclusively associated with monoclonal gammopathy. MATERIAL AND METHODS:This retrospective study summarizes the clinical characteristics of four patients with scleromyxe...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-012-0997-5

    authors: Kreuter A,Stücker M,Kolios AG,Altmeyer P,Möllenhoff K

    更新日期:2012-08-01 00:00:00

  • [A new measuring device for computer-assisted imaging of the form and flexibility of the spine].

    abstract::Our aim is to present a new method to examine spinal mobility and spine shape excluding torsional scoliosis. In comparison to measuring devices of the spine used so far, this noninvasive and easy to use method documents altered patterns of intervertebral mobility of the lumbar and thoracic spine. This may lead to a br...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:

    authors: Hauns B,Ovenhausen K,Hase P,Lorenzen W,Mennet P,Stratz T,Müller W

    更新日期:1994-05-01 00:00:00

  • [SAPHO syndrome].

    abstract::The SAPHO syndrome, an acronym for synovitis, acne, pustulosis, hyperostosis and osteitis, is a rare disease which affects bones, joints and the skin. The main osteoarticular features are hyperostosis and osteitis. Osteoarticular symptoms predominantly occur on the anterior chest wall but the spine and the peripheral ...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-014-1460-6

    authors: Heldmann F,Kiltz U,Baraliakos X,Braun J

    更新日期:2014-10-01 00:00:00

  • [Personalized medicine in cytokine-targeted therapy].

    abstract::Personalized healthcare tries to predict the effectiveness and safety in individual therapeutic approaches by defining individual patient characteristics (biomarkers), while stratification uses diagnostic patterns for groups of patients for prediction of therapeutic response with less adverse reactions caused by the d...

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-011-0886-3

    authors: Behrens F,Köhm M

    更新日期:2013-02-01 00:00:00

  • Successful combination therapy using adalimumab and 5-aminosalicylic acid for a resistant case of intestinal Behçet's disease.

    abstract::Behçet's disease (BD) is a recurrent, multisystemic, inflammatory blood vessel disorder that can result in mouth, genital, and skin ulcers; arthritis; and eye and intestinal inflammation. We describe a 21-year-old Korean female patient with intestinal BD refractory to conventional medical treatment and biologic drugs....

    journal_title:Zeitschrift fur Rheumatologie

    pub_type: 杂志文章

    doi:10.1007/s00393-020-00816-0

    authors: Kim HJ,Kim KT,Lee SG,Kim Y

    更新日期:2020-09-01 00:00:00