Abstract:
:There is concern in the UK about nonmedical use (NMU) of alprazolam (Xanax). We investigated the epidemiology of alprazolam NMU compared with diazepam using data from the Survey of Non-Medical Use of Prescription Drugs (NMURx) programme (collected 28 September-1 December 2017). The survey included 10 019 respondents and was weighted by age, sex and region to represent 52 927 659 UK adults. The estimated national prevalence of lifetime NMU of alprazolam was 0.32% (95% confidence interval: 0.19-0.46), and 1.30% (1.06-1.54) for diazepam. The prevalence of NMU in the last 90 days was significantly different when split by age category for alprazolam (P < .001), but not for diazepam (P = .262) with alprazolam NMU being more common among younger adults (age 16-24 years: 0.37%; age 25-34 years: 0.14%; 35 years or older: 0.01%). Further research is needed to fully understand the motivations of alprazolam NMU and to monitor whether the popularity of alprazolam will rise.
journal_name
Br J Clin Pharmacoljournal_title
British journal of clinical pharmacologyauthors
Hockenhull J,Amioka E,Black JC,Haynes CM,Dargan PI,Dart RC,Wood DMdoi
10.1111/bcp.13959subject
Has Abstractpub_date
2019-08-01 00:00:00pages
1841-1845issue
8eissn
0306-5251issn
1365-2125journal_volume
85pub_type
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journal_title:British journal of clinical pharmacology
pub_type: 临床试验,杂志文章
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更新日期:1983-01-01 00:00:00
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journal_title:British journal of clinical pharmacology
pub_type: 杂志文章,随机对照试验
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journal_title:British journal of clinical pharmacology
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journal_title:British journal of clinical pharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章
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journal_title:British journal of clinical pharmacology
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1998-09-01 00:00:00
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doi:10.1111/bcp.12459
更新日期:2014-12-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1111/j.1365-2125.2012.04317.x
更新日期:2013-01-01 00:00:00
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journal_title:British journal of clinical pharmacology
pub_type: 临床试验,杂志文章
doi:10.1111/j.1365-2125.1983.tb02319.x
更新日期:1983-01-01 00:00:00
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journal_title:British journal of clinical pharmacology
pub_type: 杂志文章
doi:10.1111/j.1365-2125.1983.tb02213.x
更新日期:1983-11-01 00:00:00
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journal_title:British journal of clinical pharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:British journal of clinical pharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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更新日期:2010-05-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2012-01-01 00:00:00
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更新日期:1986-03-01 00:00:00
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journal_title:British journal of clinical pharmacology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1975-04-01 00:00:00
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更新日期:2010-05-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1111/j.1365-2125.1990.tb05470.x
更新日期:1990-01-01 00:00:00
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pub_type: 临床试验,杂志文章
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更新日期:1981-11-01 00:00:00
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更新日期:2020-12-23 00:00:00
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journal_title:British journal of clinical pharmacology
pub_type: 杂志文章,评审
doi:10.1111/j.1365-2125.1989.tb03585.x
更新日期:1989-01-01 00:00:00