Essential oil from Lippia microphylla Cham. modulates nitric oxide pathway and calcium influx to exert a tocolytic effect in rat uterus.

abstract：:In this study, Box-Behnken Design was used to optimize the ultrasonic extraction of polysaccharides from quince peels (QPPs) by ascorbic acid and the effect of extraction temperature, extraction time and pH was evaluated. Under optimized conditions of temperature 90 °C, 60 min sonication time and pH = 3.26, the extrac...

journal_title：Natural product research

authors： Dammak MI,Mzoughi Z,Chakroun I,Mansour HB,Le Cerf D,Majdoub H

更新日期：2020-05-01 00:00:00

abstract：:The crystal structure and unambiguous absolute configuration of meleagrin (1) isolated from fungus Emericella dentata Nq45 is reported herein to first time on the bases of single crystal X-ray diffraction. Together with 1, haenamindole (2), isorugulosuvine (3), secalonic acid D (4), ergosterol (5) and cerebroside A (6...

journal_title：Natural product research

authors： Hamed A,Abdel-Razek AS,Araby M,Abu-Elghait M,El-Hosari DG,Frese M,Soliman HSM,Stammler HG,Sewald N,Shaaban M

更新日期：2020-03-19 00:00:00

abstract：:The main purpose of this study was the characterisation of 'Serra da Lousã' heather honey by using novel statistical methodology, relevant principal component analysis, in order to assess the correlations between production year, locality and composition. Herein, we also report its chemical composition in terms of sug...

journal_title：Natural product research

authors： Martins RC,Lopes VV,Valentão P,Carvalho JC,Isabel P,Amaral MT,Batista MT,Andrade PB,Silva BM

更新日期：2008-01-01 00:00:00

abstract：:These are the days when one would go online first seeking home remedies before seeing a doctor. Apple cider vinegar (ACV) is one such popular yet scientifically under-validated remedy. Our results prove the unequivocal antimicrobial activity of ACV to be true at full strength concentrations. However, the activity cann...

journal_title：Natural product research

authors： Gopal J,Anthonydhason V,Muthu M,Gansukh E,Jung S,Chul S,Iyyakkannu S

更新日期：2019-03-01 00:00:00

abstract：:Two new, aramatosides A and B (1 and 2), together with seven known oleanane-type triterpene saponins (3-9) were isolated from the leaves of Aralia armata. Their structures were determined by combination of HR-ESI-MS, 1 D and 2 D NMR spectral data as well as comparison with the previous literature. Compounds 6-9 exhibi...

journal_title：Natural product research

authors： Yen PH,Chuong NTH,Lien GTK,Cuc NT,Nhiem NX,Thanh NTV,Tai BH,Seo Y,Namkung W,Park S,Kim SH,Minh CV,Kiem PV

更新日期：2020-05-22 00:00:00

abstract：:This study was aimed at characterising the secondary metabolites responsible for antibacterial and antioxidant activities of Acalypha wilkesiana. Purification of the defatted methanol leaves extract was guided by the DPPH free radical scavenging assay as well as by evaluation of the antibacterial activity against four...

journal_title：Natural product research

authors： Anokwuru CP,Sinisi A,Samie A,Taglialatela-Scafati O

更新日期：2015-01-01 00:00:00

abstract：:As part of continuing our research on diverse C-7 derivatives of camptothecin (CPT), 16 CPT derivatives bearing piperazinyl-thiourea chemical scaffold and different substituent groups have been designed, synthesized and evaluated in vitro for cytotoxicity against five tumor cell lines (A-549, MDA-MB-231, MCF-7, KB and...

journal_title：Natural product research

authors： Song ZL,Yang GZ,Li JC,Liu YQ,Yang CJ,Goto M,Zhang ZJ,Morris-Natschke SL,Liu H,Lee KH

更新日期：2020-07-01 00:00:00

abstract：:The oral squamous cell carcinoma (OSCC) is the eighth more common cancer in men. The development of new and more efficient drugs is needed. Plants of the genus Piper are popularly used in the treatment of many diseases. This study evaluated the antitumor effect of extract, fraction and isolated compounds from leaves o...

journal_title：Natural product research

authors： Fonseca ACCD,de Queiroz LN,Sales Felisberto J,Jessé Ramos Y,Mesquita Marques A,Wermelinger GF,Pontes B,de Lima Moreira D,Robbs BK

更新日期：2020-10-14 00:00:00

abstract：:An HPLC/DAD/ESI-MSn method was established to characterise flavonoids in the seeds of Sophora alopecuroides L. All the flavonoids exhibited abundant [M-H]- ions, which triggered data-dependent multistage mass spectrometry fragmentations. Characteristic UV spectra were used to confirm flavonoid subtypes. In total, 22 f...

journal_title：Natural product research

authors： Yang WZ,Ye G,Meng AH,Sabir G,Qiao X,Guo DA,Ye M

更新日期：2013-03-01 00:00:00

abstract：:A minor new withanolide, named plantagiolide F, was isolated from the whole plant of Tacca plantaginea (Hance). The structure of plantagiolide F was elucidated on the basis of spectroscopic methods including extensive 1- and 2-D NMR experiments. ...

journal_title：Natural product research

authors： Yang JY,Chen CX,Zhao RH,Hao XJ,Liu HY

更新日期：2011-01-01 00:00:00

abstract：:Phytochemical investigation of the methylenechloride/methanol extract of the aerial parts of Stachys aegyptiaca afforded a new neoclerodane-type diterpene with a new side chain 1, in addition to two known diterpenes 2 and 3 and a known flavonoid glycoside 4. The structures of the compounds were determined by comprehen...

journal_title：Natural product research

authors： Mohamed Ael-H,Mohamed NS

更新日期：2014-01-01 00:00:00

abstract：:Moringa oleifera Lam. family Moringaceae is well known for a wide range of biological activities and a complex phytochemical composition. The current study investigates tissue culture protocols for Moringa oleifera leaves and seeds. For static culture initiation, Murashige and skooge (MS) as a basal medium with hormon...

journal_title：Natural product research

authors： Mustafa R,El-Naggar EMB,Svajdlenka E,Omran G,ELFiky F,El-Hawiet A

更新日期：2020-03-25 00:00:00

abstract：:Juniperus chinensis cv. Kaizuca has extensive pharmacological activities. The cone oils exhibited protein tyrosine phosphatase 1B inhibitory activity in vitro. The IC50 value was 4.49 ± 0.04 μg/mL. A total of 17 compounds were characterised from the cone oils by GC-MS. In order to explain the activity against protein ...

journal_title：Natural product research

authors： Fang C,Gu D,Yang J,Li M,Liu H,Yang Y

更新日期：2018-11-01 00:00:00

abstract：:The essential oils of sage leaves (Salvia aucheri Bentham var. canescens Boiss. & Heldr.), growing wild in South Anatolia, were extracted by hydrodistillation and analysed by GC and GC-MS. The percentage yields of the essential oils from sage leaves harvested at different years were 1.0%, 1.3%, 1.3%, 1.0%, 1.4%, 1.5% ...

journal_title：Natural product research

authors： Figueredo G,Chalchat JC,Chalard P,Özcan MM,Al Juhaimi FY

更新日期：2012-01-01 00:00:00

abstract：:The structure of pregnane oligoglycosides, namely rocinine (1) and marsdinine (11), which have been isolated from the chloroform soluble extract of the dried stem of Marsdenia roylei, were elucidated using MS, (1)H NMR, (13)C NMR, (1)H-(1)H COSY, HSQC and TOCSY experiments as well as chemical degradation and derivatis...

journal_title：Natural product research

authors： Gupta V,Kumar A,Khare A,Khare NK

更新日期：2009-01-01 00:00:00

abstract：:Cathepsin B (catB) is a cysteine protease involved in tumour progression and represents a potential therapeutic target in cancer. Among the 15 evaluated extracts from cerrado biome, Myrcia lingua Berg. (Myrtaceae) extract demonstrated to be a source of compounds with potential to inhibit catB. Using bioactivity-guided...

journal_title：Natural product research

authors： Ramalho SD,de Sousa LR,Burger MC,Lima MI,da Silva MF,Fernandes JB,Vieira PC

更新日期：2015-01-01 00:00:00

abstract：:Phytochemical investigation of Eucommia ulmoides Oliver staminate flowers provided twenty-seven compounds, including 11 triterpenes (1-11), 4 fatty acids (12-15), 1 coumarin (16), 1 chromone (17), 7 flavonoids (18-24) and 3 cyclopeptide alkaloids (25-27). Compounds 4-6, 8-9, 11-15, 17 and 25-27 were reported for the f...

journal_title：Natural product research

authors： Li R,Nie L,Wang Q,Ouyang D,Zhang L,Yuan Y,Hong Y,Wang J,Hu X

更新日期：2020-12-12 00:00:00

abstract：:Fungi are important organisms related to the production of antibiotics, many of which are commercially available and used in the clinic to treat infections. Infectious diseases represent a leading cause of death worldwide, being a severe threat to public health, especially with the rise of multi-resistant microorganis...

journal_title：Natural product research

authors： Teles AP,Ataliba GS,Takahashi JA

更新日期：2013-01-01 00:00:00

abstract：:Tryptamine derivatives such as tryptamine and bacillamides were strong algicidal compounds promising in controlling harmful algae blooms, but their bioactivity and application researches were hindered by extremely low natural production rates. This study found an induced production of algicidal tryptamine derivatives ...

journal_title：Natural product research

authors： Yu L,Hu Z,Ma Z

更新日期：2015-01-01 00:00:00

abstract：:A new isoflavone, 4'-prenyloxyvigvexin A (1) and a new pterocarpan, (6aR,11aR)-3,8-dimethoxybitucarpin B (2) were isolated from the leaves of Lonchocarpus bussei and the stem bark of Lonchocarpus eriocalyx, respectively. The extract of L. bussei also gave four known isoflavones, maximaisoflavone H, 7,2'-dimethoxy-3',4...

journal_title：Natural product research

authors： Adem FA,Kuete V,Mbaveng AT,Heydenreich M,Koch A,Ndakala A,Irungu B,Yenesew A,Efferth T

更新日期：2019-09-01 00:00:00

abstract：:Camptothecin (CPT), the derivatives of which are used clinically for the treatment of metastatic colon cancer, is isolated from intact plants that can be subjected to environmental fluctuations. In vitro cultures may be an alternate and continuous source for year-round production of CPT. Since CPT production by undiff...

journal_title：Natural product research

authors： Kamble S,Gopalakrishnan R,Eapen S

更新日期：2011-10-01 00:00:00

abstract：:A new isoflavonoid, excelsanone (2), was isolated from the ethyl acetate extract of Erythrina excelsa stem bark, together with three known compounds namely 6,8-diprenylgenistein (3), β-sitosterol (1) and sitosteryl-β-D-glucopyranoside (4). Their structures were elucidated using spectroscopic methods (HR-ESI-MS, NMR an...

journal_title：Natural product research

authors： Gbaweng AJY,Daïrou H,Zingué S,Emmanuel T,Tchinda AT,Frédérich M,Mbafor JT

更新日期：2020-03-01 00:00:00

abstract：:This study investigated the flavonoid constituents of a traditional Chinese medical plant Ziziphora clinopodioides Lam. by using ultra-performance liquid chromatography coupled with quadruple time-of-flight mass spectrometry and screened the active components in regulating autophagy.Normal rat kidney (NRK) cells trans...

journal_title：Natural product research

authors： Zhang XM,An DQ,Guo LL,Yang NH,Zhang H

更新日期：2019-09-01 00:00:00

abstract：:Two diketopiperazines were isolated from a culture of the marine-derived actinomycete Streptomyces sp. ZZ446. Their structures were elucidated as maculosin (1) and maculosin-O-α-L-rhamnopyranoside (2) based on their NMR and HRESIMS data, specific rotation, and chemical degradation. Maculosin-O-α-L-rhamnopyranoside (2)...

journal_title：Natural product research

authors： Chen S,Zhang D,Chen M,Zhang Z,Lian XY

更新日期：2020-04-01 00:00:00

abstract：:Endophytic fungi represent ubiquitous microbial organisms able to live in the tissues of different plants around the world and represent a prolific source of bioactive metabolites. In the present study, the endophytic fungus Aspergillus calidoustus was isolated from the medicinal plant Acanthospermum australe (Asterac...

journal_title：Natural product research

authors： de Carvalho CR,Vieira Mde L,Cantrell CL,Wedge DE,Alves TM,Zani CL,Pimenta RS,Sales Junior PA,Murta SM,Romanha AJ,Rosa CA,Rosa LH

更新日期：2016-01-01 00:00:00

abstract：:(+) Benzomalvins E (1) and (-) Benzomalvins E (2), a pair of epimeric derivatives, together with three known benzomalvins (3-5), were isolated from solid cultures of a interrhizospheric fungus Penicillium sp. SYPF 8411. The planar structure of (+) Benzomalvins E (1) has been previously reported. While, the absolute co...

journal_title：Natural product research

authors： Feng QM,Feng Y,Zhang TY,Wang HF,Zhang MY,Wu YY,Chen G,Zhang YX,Pei YH

更新日期：2020-07-01 00:00:00

abstract：:In this study, the effects of Benzoinum and Styrax on Escherichia coli (E. coli) growth were investigated by microcalorimetry. Using a TAM Air Isothermal Calorimeter, ampoule method, the power-time curves of E. coli growth at 37°C affected by Benzoinum and Styrax were measured. By analysing some quantitative thermokin...

journal_title：Natural product research

authors： Wang J,Cheng D,Zeng N,Xia H,Fu Y,Yan D,Zhao Y,Xiao X

更新日期：2011-02-01 00:00:00

abstract：:The proposed work, aims to provide a "green" and cutting-edge technique for the mordanting and dyeing of polyester fabric with natural henna dye using the advanced technology of micro waves. For providing a complete "green" and ecofriendly dyeing process, lemon was used as a natural bio mordant with micro waves and re...

journal_title：Natural product research

authors： Arain RA,Ahmad F,Khatri Z,Peerzada MH

更新日期：2021-01-01 00:00:00

abstract：:In this computational study, geometric factors are calculated by applying semi-empirical methods (PM3) that support experimental evidence from this lab where bryostatins can bind trivalent iron with six Fe-O bonds forming an octahedral geometry. The geometric factors are calculated for all 20 structures (Fe3+ bound to...

journal_title：Natural product research

authors： Manning TJ,Thomas J,Osiro S,Smith J,Abadi G,Noble L,Phillips D

更新日期：2008-03-20 00:00:00

abstract：:Two new flavonoid glycosides, kaempferol 3-O-α-L-rhamnopyranosyl (1→6) (3''-acetyl)-β-D-galactopyranoside 1 and kaempferol 3-O-α-L-arabinopyranosyl-5-O-α-L-rhamnopyranoside 2, along with six known ones 3-8 were isolated from the flowers of Vicia faba L. (Fabaceae). Methanol extract and the isolated compounds were test...

journal_title：Natural product research

authors： Allam AE,Nafady AM,Nakagawa T,Takemoto N,Shimizu K

更新日期：2018-08-01 00:00:00