Methylglyoxal-Induced Retinal Angiogenesis in Zebrafish Embryo: A Potential Animal Model of Neovascular Retinopathy.

abstract：:There is growing evidence that chronic inflammation plays a role in both the development and progression of diabetic retinopathy. There is also evidence that molecules produced as a result of hyperglycemia can activate microglia. However the exact contribution of microglia, the resident immune cells of the central ner...

journal_title：Journal of ophthalmology

authors： Grigsby JG,Cardona SM,Pouw CE,Muniz A,Mendiola AS,Tsin AT,Allen DM,Cardona AE

更新日期：2014-01-01 00:00:00

abstract：:Purpose. To measure the chemotherapeutic effects of focal melphalan (intravitreal and subconjunctival) on tumor burden, hypoxia, and vasculature in LHBETATAG murine retinoblastoma model. Methods. LHBETATAG transgenic mice were treated with a single 1 mcg intravitreal injection of melphalan, 100 mcg subconjunctival inj...

journal_title：Journal of ophthalmology

authors： Shah NV,Pham DG,Murray TG,Decatur C,Hernandez E,Shah NN,Cavalcante M,Houston SK

更新日期：2014-01-01 00:00:00

abstract：Objective:This study aims to describe the clinical manifestations and outcomes in a cohort of older Chinese patients. Method:A retrospective study of patients aged ≥ 45 years who had a first episode of optic neuritis (ON) between May 2008 and November 2012. Clinical features at onset and last follow-up were analyzed w...

journal_title：Journal of ophthalmology

authors： Wang J,Zhou H,Qin L,Peng C,Zhao J,Teng D,Lin D,Ai N,Xu Q,Wei S

更新日期：2017-01-01 00:00:00

abstract：:Aim. To examine subscale and total scores of NEI-VFQ questionnaire of type 2 diabetes patients at different diabetic retinopathy (DRP) stages. Methods. A total number of 201 patients have been included. Prior to ophthalmological examination all patients participated in the NEI-VFQ questionnaire. The patients were divi...

journal_title：Journal of ophthalmology

authors： Akkaya S,Düzova S,Şahin Ö,Kazokoğlu H,Bavbek T

更新日期：2016-01-01 00:00:00

abstract：:Fifty-two eyes of 52 patients with treatment-naïve macular edema associated with perfused branch retinal vein occlusion were retrospectively reviewed. Twenty-seven cases received PRN intravitreal bevacizumab, and 25 cases were treated by PRN intravitreal aflibercept with monthly follow-ups for 12 months. Both afliberc...

journal_title：Journal of ophthalmology

authors： Wang JK,Su PY,Hsu YR,Chen YJ,Chen FT,Tseng YY

更新日期：2016-01-01 00:00:00

abstract：:Purpose. To evaluate the relationship between internal carotid artery (ICA) stenosis and subfoveal choroidal thickness (SFCT) in the elderly population. Methods. A total of 42 eyes of 21 patients with more than 70% ICA stenosis (Group 1) on one side and less than 70% stenosis (Group 2) on the other side were recruited...

journal_title：Journal of ophthalmology

authors： Akçay Bİ,Kardeş E,Maçin S,Ünlü C,Özgürhan EB,Maçin A,Bozkurt TK,Ergin A,Surmeli R

更新日期：2016-01-01 00:00:00

abstract：:Glaucoma is one of the leading causes of blindness worldwide. Recent studies suggest that intraocular pressure (IOP) fluctuations, peaks, and rhythm are important factors in disease advancement. Yet, current glaucoma management remains hinged on single IOP measurements during clinic hours. To overcome this limitation,...

journal_title：Journal of ophthalmology

authors： Xu SC,Gauthier AC,Liu J

更新日期：2016-01-01 00:00:00

abstract：Purpose:To evaluate intraoperative complications and utilization of adjunctive devices between microscope and intracameral illuminations during cataract surgery in the elderly over 75 years. Design:A retrospective, consecutive, interventional case series Participants. Two hundred eighty-six eyes of 184 patients older ...

journal_title：Journal of ophthalmology

authors： Kim YJ,Park SJ,Lee JY,Lee DY,Nam DH

更新日期：2019-01-10 00:00:00

abstract：Purpose:To examine the current knowledge about the age-related processes in the anterior segment of the eye at a biological, clinical, and molecular level. Methods:We reviewed the available published literature that addresses the aging process of the anterior segment of the eye and its associated molecular and physiol...

journal_title：Journal of ophthalmology

authors： Hernandez-Zimbron LF,Gulias-Cañizo R,Golzarri MF,Martínez-Báez BE,Quiroz-Mercado H,Gonzalez-Salinas R

更新日期：2017-01-01 00:00:00

abstract：Purpose:To evaluate early changes in visual function and visual quality parameters after Descemet membrane endothelial keratoplasty (DMEK) and to compare the outcomes with healthy controls. Methods:Thirteen patients who underwent DMEK and 14 controls were evaluated. All subjects underwent visual function evaluation, i...

journal_title：Journal of ophthalmology

authors： Satue M,Idoipe M,Gavin A,Romero-Sanz M,Liarakos VS,Mateo A,Garcia-Martin E,Blasco-Martinez A,Sanchez-Perez A

更新日期：2018-09-23 00:00:00

abstract：:Background. The effect of angiotensin converting enzyme inhibitors (ACEi) on regression of retinopathy in type 2 diabetics is still ill defined. Methods. We compared the incidence of retinopathy regression in 90 hypertensive type 2 diabetics randomized to at least 3-year blinded ACEi with trandolapril (2 mg/day) or no...

journal_title：Journal of ophthalmology

authors： Ruggenenti P,Iliev I,Filipponi M,Tadini S,Perna A,Ganeva M,Ene-Iordache B,Cravedi P,Trevisan R,Bossi A,Remuzzi G

更新日期：2010-01-01 00:00:00

abstract：:The retinal degeneration 11 (rd11) mouse is a new animal model with rapid photoreceptor degeneration. The long-term efficacy of gene therapy has a direct relationship with the onset of photoreceptor degeneration or apoptosis, whereas the degeneration or apoptosis patterns of photoreceptors are still unclear in rd11 mi...

journal_title：Journal of ophthalmology

authors： Zhang H,Li X,Dai X,Han J,Zhang Y,Qi Y,He Y,Liu Y,Chang B,Pang JJ

更新日期：2017-01-01 00:00:00

abstract：Purpose:Bilateral choroidal ganglioneuroma is extremely rare, and no cases have been described in the literature. Multimodal images are crucial for its diagnosis. Here, we evaluated multimodal images in the early stage of choroidal ganglioneuroma. Methods:A 6-year-old boy was recruited who had experienced gradually pr...

journal_title：Journal of ophthalmology

authors： Jiang Z,Zhang T,Liu X,Liang D,Zhong Y,Chan CC,Ding X

更新日期：2020-05-11 00:00:00

abstract：:The functional visual acuity test which is the average of the visual acuities measured during a specific time frame (standard, 60 seconds) has been used recently to assess the visual function in various conditions. The availability of a shorter version of the functional visual acuity test promises to be patient friend...

journal_title：Journal of ophthalmology

authors： Hidaka Y,Masui S,Nishi Y,Ayaki M,Kaido M,Mimura M,Tsubota K,Negishi K

更新日期：2019-09-10 00:00:00

abstract：Purpose:The aim of this study was to assess the effects of residual anterior lens epithelial cell (LEC) removal by anterior capsule polishing on the effective lens position (ELP) and axial position stability of the intraocular lens (IOL) after cataract surgery via postoperative measurement of the anterior chamber depth...

journal_title：Journal of ophthalmology

authors： Bang SP,Yoo YS,Jun JH,Joo CK

更新日期：2018-08-19 00:00:00

abstract：Purpose:To ascertain wet AMD (wAMD) management patterns in Spain. Methods:A two-round Delphi study conducted through a questionnaire-based survey designed from literature review and validated by an independent Steering Committee. Results:Forty-nine retina specialists experienced in wAMD participated by answering the ...

journal_title：Journal of ophthalmology

authors： García-Layana A,García-Arumí J,Figueroa MS,Arias Barquet L,Ruíz-Moreno JM,Monclús-Arbona L,The Spanish Amd Multicenter Group

更新日期：2019-09-30 00:00:00

abstract：:Purpose. To evaluate the relationship between the macular ganglion cell complex (mGCC) thickness, which is the sum of the retinal nerve fiber, ganglion cell, and inner plexiform layers, measured with a spectral-domain optical coherence tomograph and the optic nerve head topography measured with a confocal scanning las...

journal_title：Journal of ophthalmology

authors： Takagi ST,Kita Y,Takeyama A,Tomita G

更新日期：2011-01-01 00:00:00

abstract：Purpose:The iStent provides a direct pathway for aqueous outflow from the anterior chamber to Schlemm's canal in patients with open-angle glaucoma (OAG). We performed a meta-analysis to evaluate the effectiveness of iStent as a standalone operation in patients with OAG in reducing the intraocular pressure (IOP) and the...

journal_title：Journal of ophthalmology

authors： Chen YY,Lai YJ,Yen YF,Huang LY

更新日期：2020-05-24 00:00:00

abstract：:Purpose. To evaluate the effectiveness and safety of perfluorohexyloctane (F6H8) for intraoperative flattening of the retina and of F6H8/silicone oil (SO) 1000 cSt as a postoperative tamponade for inferior retinal detachment with inferior proliferative vitreoretinopathy. Methods. This is a retrospective review of 22 p...

journal_title：Journal of ophthalmology

authors： Tosi GM,Marigliani D,Bacci T,Romeo N,Balestrazzi A,Martone G,Caporossi T

更新日期：2014-01-01 00:00:00

abstract：Objective:To calculate the Q values from the human anterior corneal surface with the tangential radius of curvature and analyze its distribution characteristics in different age and refractive status groups. Methods:Tangential power maps of the anterior cornea from Orbscan II were acquired for 201 subjects' right eyes...

journal_title：Journal of ophthalmology

authors： Xia Z,Lin C,Huang X,Ying J,Shi M,Zheng S

更新日期：2018-04-17 00:00:00

abstract：:Purpose. This study investigated the effects of oral propolis on the progression of galactose-induced sugar cataracts in rats and the in vitro effects of propolis on high-glucose-induced reactive oxygen species (ROS) and cell death in cultured rat lens cells (RLECs). Methods. Galactose-fed rats and RLECs cultured in h...

journal_title：Journal of ophthalmology

authors： Shibata T,Shibata S,Shibata N,Kiyokawa E,Sasaki H,Singh DP,Kubo E

更新日期：2016-01-01 00:00:00

abstract：AIM:To discuss the clinical characteristics of immune-related dry eye. METHODS:Simple dry eye (SDE) group: we selected 224 patients of simple dry eye with no systemic lesions. Immune-related dry eye (IRDE) group: we selected 207 patients of dry eye complicated with immune system diseases, including 70 cases of Sjögren...

journal_title：Journal of ophthalmology

authors： Wang H,Wang PB,Chen T,Zou J,Li YJ,Ran XF,Li QX

更新日期：2017-01-01 00:00:00

abstract：:Background. The vision with diffractive toric multifocal intraocular lenses after cataract surgery in long eyes has not been studied previously. Objectives. To report visual performance after bilateral implantation of a diffractive toric multifocal intraocular lens in high myopes. Methods. Prospective, observational c...

journal_title：Journal of ophthalmology

authors： Chang JS,Chan VK,Ng JC,Law AK

更新日期：2016-01-01 00:00:00

abstract：:Purpose. To evaluate visual and safety outcomes of 23-gauge (G) pars plana vitrectomy (PPV) with application of perfluorocarbon liquid (PFCL) for intraoperative protection of the macula during intraocular foreign body (IOFB) removal. Methods. Retrospective study of 42 patients who underwent 23 G PPV for IOFB removal f...

journal_title：Journal of ophthalmology

authors： Rejdak R,Choragiewicz T,Moneta-Wielgos J,Wrzesinska D,Borowicz D,Forlini M,Jünemann AG,Nowomiejska K

更新日期：2017-01-01 00:00:00

abstract：:Objective. To describe the clinicoradiological and histopathological findings in a case of lacrimal gland enlargement secondary to lymphomatoid granulomatosis (LG) and to review the literature. Design. Case report and systematic literature review. Methods. A 75-year-old woman presented with right ptosis. Computerised ...

journal_title：Journal of ophthalmology

authors： Pradeep TG,Cannon P,Dodd T,Selva D

更新日期：2010-01-01 00:00:00

abstract：Purpose:To investigate the correlation between decentration index (index of height decentration, IHD) automatically calculated by the Pentacam HR software and the manually calculated inferior minus superior (I-S) value. Setting:Al Watany Eye Hospital, Cairo, Egypt. Methods:In a retrospective study, history taking, cl...

journal_title：Journal of ophthalmology

authors： Wahba SS,Roshdy MM,Fikry RR,Abdellatif MK,Abodarahim AM

更新日期：2018-10-02 00:00:00

abstract：:Current data permit only speculations regarding sex differences in the prevalence of infectious uveitis between women and men because uveitis case surveys do not uniformly report gender data. Differences in prevalence that are reported in the literature could relate to simple differences in the number of women and men...

journal_title：Journal of ophthalmology

authors： Davis JL

更新日期：2014-01-01 00:00:00

abstract：:Purpose. To compare anterior chamber depth (ACD), representing the distance between the anterior corneal surface and anterior lens surface measurements between the Galilei Dual Scheimpflug Analyzer and the IOLMaster. Methods. A retrospective review of 65 individual patient eyes with normal anterior segments, and no pr...

journal_title：Journal of ophthalmology

authors： Patel RP,Pandit RT

更新日期：2012-01-01 00:00:00

abstract：:Genome-wide association study (GWAS) analysis identified three new susceptibility loci for PACG. In this study, we aimed to investigate whether these three loci in PLEKHA7, COL11A1, and PCMTD1-ST18 are associated with PAC and ocular biometric characteristics, such as axial length (AL), anterior chamber depth (ACD), an...

journal_title：Journal of ophthalmology

authors： Shi H,Zhu R,Hu N,Shi J,Zhang J,Jiang L,Jiang H,Guan H

更新日期：2013-01-01 00:00:00

abstract：Purpose:To evaluate the outcomes of femtosecond laser-assisted implantation of a 355-degree intracorneal ring (ICR) (Keraring) in patients with keratoconus in the three-year follow-up. Setting:Future Femtolaser Center, Sohag, Egypt. Design:Prospective interventional case series. Patients and Methods:A prospective ca...

journal_title：Journal of ophthalmology

authors： Abdellah MM,Ammar HG

更新日期：2019-10-09 00:00:00