Immunostimulatory functions of adoptively transferred MDSCs in experimental blunt chest trauma.

abstract：:On standard electrocardiogram (ECG) PQ interval is known to be moderately heart rate dependent, but no physiologic details of this dependency have been established. At the same time, PQ dynamics is a clear candidate for non-invasive assessment of atrial abnormalities including the risk of atrial fibrillation. We studi...

journal_title：Scientific reports

authors： Toman O,Hnatkova K,Smetana P,Huster KM,Šišáková M,Barthel P,Novotný T,Schmidt G,Malik M

更新日期：2020-02-13 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with aggregation of TAR DNA-binding protein-43 (TDP-43) in neuronal cells and manifests as motor neuron dysfunction &muscle atrophy. The carboxyl-terminal prion-like domain of TDP-43 can aggregate in vitro into toxic β-sheet rich amylo...

journal_title：Scientific reports

authors： Prasad A,Raju G,Sivalingam V,Girdhar A,Verma M,Vats A,Taneja V,Prabusankar G,Patel BK

更新日期：2016-12-21 00:00:00

abstract：:The endo-levanase BT1760 of a human gut commensal Bacteroides thetaiotaomicron randomly cuts a β-2,6-linked fructan, levan, into fructo-oligosaccharides providing a prebiotic substrate for gut microbiota. Here we introduce the crystal structure of BT1760 at resolution of 1.65 Å. The fold of the enzyme is typical for G...

journal_title：Scientific reports

authors： Ernits K,Eek P,Lukk T,Visnapuu T,Alamäe T

更新日期：2019-06-11 00:00:00

abstract：:Most bacterial cells are stressed, and as a result, some become tolerant to antibiotics by entering a dormant state known as persistence. The key intracellular metabolite that has been linked to this persister state is guanosine tetraphosphate (ppGpp), the alarmone that was first linked to nutrient stress. In Escheric...

journal_title：Scientific reports

authors： Chowdhury N,Kwan BW,Wood TK

更新日期：2016-02-03 00:00:00

abstract：:The early detection of cognitive impairment or dementia is in the focus of current research as the amount of cognitively impaired individuals will rise intensely in the next decades due to aging population worldwide. Currently available diagnostic tools to detect mild cognitive impairment (MCI) or dementia are time-co...

journal_title：Scientific reports

authors： Müller S,Herde L,Preische O,Zeller A,Heymann P,Robens S,Elbing U,Laske C

更新日期：2019-03-05 00:00:00

abstract：:The aim of the present study was to evaluate the healthy lifestyle behaviors in hypertensive patients (aware, n = 1364 and not aware, n = 1213) based on 2011 national survey of risk factors of non-communicable disease (SuRFNCD) of Iran. Lifestyle score was calculated based on lifestyle behaviors, including smoking sta...

journal_title：Scientific reports

authors： Akbarpour S,Khalili D,Zeraati H,Mansournia MA,Ramezankhani A,Fotouhi A

更新日期：2018-05-31 00:00:00

abstract：:Soluble starch synthase I (SSI) is a key enzyme in the biosynthesis of plant amylopectin. In this study, the gene named IbSSI, was cloned from sweet potato, an important starch crop. A high expression level of IbSSI was detected in the leaves and storage roots of the sweet potato. Its overexpression significantly incr...

journal_title：Scientific reports

authors： Wang Y,Li Y,Zhang H,Zhai H,Liu Q,He S

更新日期：2017-05-24 00:00:00

abstract：:We investigated the physiological functions of Myo10 (myosin X) using Myo10 reporter knockout (Myo10tm2) mice. Full-length (motorized) Myo10 protein was deleted, but the brain-specific headless (Hdl) isoform (Hdl-Myo10) was still expressed in homozygous mutants. In vitro, we confirmed that Hdl-Myo10 does not induce fi...

journal_title：Scientific reports

authors： Bachg AC,Horsthemke M,Skryabin BV,Klasen T,Nagelmann N,Faber C,Woodham E,Machesky LM,Bachg S,Stange R,Jeong HW,Adams RH,Bähler M,Hanley PJ

更新日期：2019-01-24 00:00:00

abstract：:To study quantitatively replicative senescence as a tumor suppressor mechanism, we investigate the distribution of a growing clonal cell population restricted by Hayflick's limit. We find that in the biologically relevant range of parameters, if the imbalance between cell division and death is moderate or low (high de...

journal_title：Scientific reports

authors： Rodriguez-Brenes IA,Wodarz D,Komarova NL

更新日期：2015-12-09 00:00:00

abstract：:Pharmaceutical applications of methylene blue, especially as photosensitizer, have been limited due to its rapid enzymatic reduction in the biological systems. In this study nano-platelet zirconium phosphate was synthesized and its biocompatibility was evaluated. The synthesized material was considered as drug deliver...

journal_title：Scientific reports

authors： Hosseinzadeh R,Khorsandi K

更新日期：2019-10-17 00:00:00

abstract：:Over-exploitation of groundwater and marked changes in climate over the years have imposed immense pressure on the global groundwater resources. As demand of potable water increases across the globe for human consumption, agriculture and industrial uses, the need to evaluate the groundwater potential and productivity ...

journal_title：Scientific reports

authors： Arulbalaji P,Padmalal D,Sreelash K

更新日期：2019-02-14 00:00:00

abstract：:Flattening of a carbon nanotube results in the formation of a carbon nanoribbon with well-defined edges. In addition, a switching of the flattening direction by about a right angle yields a carbon nanotetrahedron at the switching point in a nanoribbon. Here, we report that chains of carbon nanotetrahedra/nanoribbons a...

journal_title：Scientific reports

authors： Kohno H,Hasegawa T

更新日期：2015-02-12 00:00:00

abstract：:The structure of metallic glasses is a long-standing question because the lack of long-range order makes diffraction based techniques difficult to be applied. Here, we used scanning tunneling microscopy with large tunneling resistance of 6 GΩ at low temperature in order to minimize forces between probe and sample and ...

journal_title：Scientific reports

authors： Pawlak R,Marot L,Sadeghi A,Kawai S,Glatzel T,Reimann P,Goedecker S,Güntherodt HJ,Meyer E

更新日期：2015-08-13 00:00:00

abstract：:Stress is one of major factors that cause sleep problems. Hypocretin represents a stress-related neuropeptide and is well known in maintaining physiological wakefulness. The hypocretinergic neurons originate in the lateral hypothalamic area (LHA) and transmit to several brain regions, including the median raphe nuclei...

journal_title：Scientific reports

authors： Hsiao YT,Lo Y,Yi PL,Chang FC

更新日期：2019-06-03 00:00:00

abstract：:Glucose homeostasis is regulated by insulin, which is produced in the β-cells of the pancreas. The synthesis of insulin is controlled by several transcription factors including PDX-1, USF1 and USF2. Both, PDX-1 and USF1 were identified as substrates for protein kinase CK2. Here, we have analysed the interplay of PDX-1...

journal_title：Scientific reports

authors： Spohrer S,Groß R,Nalbach L,Schwind L,Stumpf H,Menger MD,Ampofo E,Montenarh M,Götz C

更新日期：2017-11-27 00:00:00

abstract：:Transport of mesoscale particles due to driving flow fields or external forces on a periodic surface appears in many areas. Geometrical and physical characteristics of particles affect the velocities of the particles in these periodic landscapes. In this paper, we present a numerical simulation based on solving the La...

journal_title：Scientific reports

authors： Madadi E,Biagooi M,Mohammadjafari F,Nedaaee Oskoee S

更新日期：2020-10-26 00:00:00

abstract：:Living organisms in drying environments build anisotropic structures and exhibit directionality through self-organization of biopolymers. However, the process of macro-scale assembly is still unknown. Here, we introduce a dissipative structure through a non-equilibrium process between hydration and deposition in the d...

journal_title：Scientific reports

authors： Okeyoshi K,Okajima MK,Kaneko T

更新日期：2017-07-21 00:00:00

abstract：:Metal sulfide (MS, nickel sulfide/copper sulfide) hollow spheres with hierarchical, ultrathin shell structures have been constructed by a facile method. The as-formed MS hollow structures are shown to be uniform in sizes with hierarchical ultrathin shells, which could facilitate the transport of electrolyte ions. Elec...

journal_title：Scientific reports

authors： Chen Z,Zhao M,Lv X,Zhou K,Jiang X,Ren X,Mei X

更新日期：2018-01-08 00:00:00

abstract：:A sensitive and specific liquid chromatographic/tandem mass spectrometric (LC-MS/MS) method was developed and validated for quantifying total and unbound docetaxel drug concentrations in plasma. Calibration curves for unbound and total docetaxel were linear over the respective ranges of 0.108~10.8 and 0.54~216 ng/mL. ...

journal_title：Scientific reports

authors： Sheu MT,Wu CY,Su CY,Ho HO

更新日期：2017-11-06 00:00:00

abstract：:Mammalian cytokinetic abscission is mediated by the ESCRT membrane fission machinery. While much has been clarified on the topology and kinetics of abscission through high-resolution microscopy, key questions regarding the mechanism of abscission remain open. Here we apply cryogenic soft-X-ray tomography to elucidate ...

journal_title：Scientific reports

authors： Sherman S,Kirchenbuechler D,Nachmias D,Tamir A,Werner S,Elbaum M,Elia N

更新日期：2016-06-10 00:00:00

abstract：:Prostate cancer (PCa) is the most common malignancy and second leading cause of cancer-related deaths in American men. Proliferating cells have higher need for nutrients and oxygen, triggering angiogenesis that plays a critical role in tumor growth, progression and metastasis. Consequently, immense focus has converged...

journal_title：Scientific reports

authors： da Silva RF,Dhar D,Raina K,Kumar D,Kant R,Cagnon VHA,Agarwal C,Agarwal R

更新日期：2018-06-22 00:00:00

abstract：:We report, for the first time, the generation of high-order harmonics in a spectral range between 200 eV and 1 keV with an unusual spectral property: only every 4(th) (4i + 1, i∈ℵ) harmonic line appears, whereas the usual high-harmonic spectra consist of every odd (2i + 1) harmonic. We attribute this unique property t...

journal_title：Scientific reports

authors： Seres J,Seres E,Landgraf B,Ecker B,Aurand B,Kuehl T,Spielmann C

更新日期：2014-02-28 00:00:00

abstract：:The temperature dependence of the resistivity (ρ) of Ag-doped Bi2Se3 (AgxBi2-xSe3) shows insulating behavior above 35 K, but below 35 K, ρ suddenly decreases with decreasing temperature, in contrast to the metallic behavior for non-doped Bi2Se3 at 1.5-300 K. This significant change in transport properties from metalli...

journal_title：Scientific reports

authors： Uesugi E,Uchiyama T,Goto H,Ota H,Ueno T,Fujiwara H,Terashima K,Yokoya T,Matsui F,Akimitsu J,Kobayashi K,Kubozono Y

更新日期：2019-03-29 00:00:00

abstract：:By means of first principles calculation and experiments, a detailed mechanism is proposed to include the stages of slip, adjustment, and expansion for the HCP → FCC phase transformation with the prismatic relation of [Formula: see text] and [Formula: see text] in titanium. It is revealed that the formation of four FC...

journal_title：Scientific reports

authors： Yang JX,Zhao HL,Gong HR,Song M,Ren QQ

更新日期：2018-01-31 00:00:00

abstract：:Alcohol use disorder (AUD) is a chronic and relapsing disease with a substantial genetic influence. Given the recent discovery of the association of PPM1G methylation with alcohol use disorder (AUD) from a genome-wide methylation study, we sought to verify and extend the previous work of AUD-related impulsivity in a K...

journal_title：Scientific reports

authors： Park CI,Kim HW,Hwang SS,Kang JI,Kim SJ

更新日期：2020-03-26 00:00:00

abstract：:We derive the stationary probability distribution for a non-equilibrium system composed by an arbitrary number of degrees of freedom that are subject to Gaussian colored noise and a conservative potential. This is based on a multidimensional version of the Unified Colored Noise Approximation. By comparing theory with ...

journal_title：Scientific reports

authors： Maggi C,Marconi UM,Gnan N,Di Leonardo R

更新日期：2015-05-29 00:00:00

abstract：:Leukemia cells are superior to hematopoietic cells with a normal differentiation potential in buffering cellular stresses, but the underlying mechanisms for this leukemic advantage are not fully understood. Using CRISPR/Cas9 deletion of the canonical autophagy-essential gene Atg7, we found that erythroleukemia K562 ce...

journal_title：Scientific reports

authors： Wang J,Fang Y,Yan L,Yuan N,Zhang S,Xu L,Nie M,Zhang X,Wang J

更新日期：2016-04-19 00:00:00

abstract：:The Hauraki Gulf, a shallow embayment in north-eastern New Zealand, provides an interesting environment for ecological soundscape research. It is situated on a tectonic plate boundary, contains one of the busiest ports in the southern hemisphere and is home to a diverse range of soniferous animals. The underwater soun...

journal_title：Scientific reports

authors： Putland RL,Constantine R,Radford CA

更新日期：2017-07-18 00:00:00

abstract：:Breast cancer in young women is typically with higher proportion of adverse pathological features. Breast cancer with BRCA1 mutation is often early-onset, and is usually associated with triple negative phenotpe. In this study, we aim to analyze the clinicopathological characteristics and prognosis in young breast canc...

journal_title：Scientific reports

authors： Wei JT,Huang WH,Du CW,Qiu SQ,Wei XL,Liu J,Zhang GJ

更新日期：2014-06-19 00:00:00

abstract：:Vaginal microbiota is an important early source of bacterial colonization for newborns. However, only a few small studies have investigated the composition of vaginal microbiota during labor. In this work, we analyzed vaginal swabs collected at 36 weeks gestation and at the onset of labor from 256 women participating ...

journal_title：Scientific reports

authors： Avershina E,Slangsvold S,Simpson MR,Storrø O,Johnsen R,Øien T,Rudi K

更新日期：2017-12-14 00:00:00