Abstract:
:Iodine thyroid blocking (ITB) suppresses the uptake of iodine to the thyroid and reduces internal doses after radioiodine intake; however, its disturbance of thyroid biokinetics causes considerable uncertainty in the use of dosimetric data intended for assessment of unblocked normal thyroid. To more accurately assess internal dose after ITB, practical dosimetry methods were proposed that consider the ITB effect in a dosimetric manner. A method using the ratio of urine excretion to thyroid retention activity was proposed to retrospectively determine individual-specific ITB levels; bioassay functions and dose coefficients corresponding to ITB levels were calculated separately using the latest biokinetic model and fundamental data. Moreover, insensitive measurement points of time, which led to similar results regardless of ITB level, were determined based on the dose per unit content. Proposed insensitive points for inhalation of vapour forms and particulate forms, respectively, were 1.5 days and 2 days after exposure.
journal_name
Radiat Prot Dosimetryjournal_title
Radiation protection dosimetryauthors
Kwon TE,Park M,Jung GH,Chung Y,Ha WH,Jin YWdoi
10.1093/rpd/ncz139subject
Has Abstractpub_date
2019-12-31 00:00:00pages
69-76issue
1eissn
0144-8420issn
1742-3406pii
5499287journal_volume
187pub_type
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