当前位置： SCI文献检索 > Scientific Reports期刊下所有文献 > A Joint Modeling Approach for Childhood Meat, Fish and Egg Consumption and the Risk of Advanced Islet Autoimmunity.

A Joint Modeling Approach for Childhood Meat, Fish and Egg Consumption and the Risk of Advanced Islet Autoimmunity.

Abstract：

:Several dietary factors have been suspected to play a role in the development of advanced islet autoimmunity (IA) and/or type 1 diabetes (T1D), but the evidence is fragmentary. A prospective population-based cohort of 6081 Finnish newborn infants with HLA-DQB1-conferred susceptibility to T1D was followed up to 15 years of age. Diabetes-associated autoantibodies and diet were assessed at 3- to 12-month intervals. We aimed to study the association between consumption of selected foods and the development of advanced IA longitudinally with Cox regression models (CRM), basic joint models (JM) and joint latent class mixed models (JLCMM). The associations of these foods to T1D risk were also studied to investigate consistency between alternative endpoints. The JM showed a marginal association between meat consumption and advanced IA: the hazard ratio adjusted for selected confounding factors was 1.06 (95% CI: 1.00, 1.12). The JLCMM identified two classes in the consumption trajectories of fish and a marginal protective association for high consumers compared to low consumers: the adjusted hazard ratio was 0.68 (0.44, 1.05). Similar findings were obtained for T1D risk with adjusted hazard ratios of 1.13 (1.02, 1.24) for meat and 0.45 (0.23, 0.86) for fish consumption. Estimates from the CRMs were closer to unity and CIs were narrower compared to the JMs. Findings indicate that intake of meat might be directly and fish inversely associated with the development of advanced IA and T1D, and that disease hazards in longitudinal nutritional epidemiology are more appropriately modeled by joint models than with naive approaches.

journal_name

Sci Rep

journal_title

Scientific reports

authors

Syrjälä E,Nevalainen J,Peltonen J,Takkinen HM,Hakola L,Åkerlund M,Veijola R,Ilonen J,Toppari J,Knip M,Virtanen SM

doi

10.1038/s41598-019-44196-1

subject

Has Abstract

pub_date

2019-05-23 00:00:00

pages

7760

issue

1

issn

2045-2322

pii

10.1038/s41598-019-44196-1

journal_volume

9

pub_type

杂志文章

相关文献

Scientific Reports文献大全
  • A Direct Comparison of Two Densely Sampled HIV Epidemics: The UK and Switzerland.

    abstract：:Phylogenetic clustering approaches can elucidate HIV transmission dynamics. Comparisons across countries are essential for evaluating public health policies. Here, we used a standardised approach to compare the UK HIV Drug Resistance Database and the Swiss HIV Cohort Study while maintaining data-protection requirement...

    journal_title：Scientific reports

    pub_type： 杂志文章,多中心研究

    doi：10.1038/srep32251

    authors： Ragonnet-Cronin ML,Shilaih M,Günthard HF,Hodcroft EB,Böni J,Fearnhill E,Dunn D,Yerly S,Klimkait T,Aubert V,Yang WL,Brown AE,Lycett SJ,Kouyos R,Brown AJ

    更新日期：2016-09-19 00:00:00

  • Artificial photosynthesis of oxalate and oxalate-based polymer by a photovoltaic reactor.

    abstract：:A photovoltaic reactor was designed for artificial photosynthesis, based on the reactions involved in high energy hydrogen atoms, which were produced from water electrolysis. Water and CO2, under the conditions studied, were converted to oxalate (H2C2O4) and a polymer. This was the first time that the oxalates and oxa...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep03572

    authors： Nong G,Chen S,Xu Y,Huang L,Zou Q,Li S,Mo H,Zhu P,Cen W,Wang S

    更新日期：2014-01-06 00:00:00

  • Microstructural deformation observed by Mueller polarimetry during traction assay on myocardium samples.

    abstract：:Despite recent advances, the myocardial microstructure remains imperfectly understood. In particular, bundles of cardiomyocytes have been observed but their three-dimensional organisation remains debated and the associated mechanical consequences unknown. One of the major challenges remains to perform multiscale obser...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-76820-w

    authors： Tueni N,Vizet J,Genet M,Pierangelo A,Allain JM

    更新日期：2020-11-25 00:00:00

  • Impact of pore anisotropy on the thermal conductivity of porous Si nanowires.

    abstract：:Porous materials display enhanced scattering mechanisms that greatly influence their transport properties. Metal-assisted chemical etching (MACE) enables fabrication of porous silicon nanowires starting from a doped Si wafer by using a metal template that catalyzes the etching process. Here, we report on the low therm...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-30223-0

    authors： Ferrando-Villalba P,D'Ortenzi L,Dalkiranis GG,Cara E,Lopeandia AF,Abad L,Rurali R,Cartoixà X,De Leo N,Saghi Z,Jacob M,Gambacorti N,Boarino L,Rodríguez-Viejo J

    更新日期：2018-08-24 00:00:00

  • Purification, Characterization and Mechanistic Evaluation of Angiotensin Converting Enzyme Inhibitory Peptides Derived from Zizyphus Jujuba Fruit.

    abstract：:The synthetic Angiotensin Converting Enzyme (ACE) inhibitors have side effects and hence demands for natural ACE inhibitors have been rising. The aim of this study is to purify and introduce natural ACE inhibitors extracted from Zizyphus jujuba fruits. Proteins from Zizyphus jujuba were lysed by trypsin, papain and th...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-60972-w

    authors： Memarpoor-Yazdi M,Zare-Zardini H,Mogharrab N,Navapour L

    更新日期：2020-03-04 00:00:00

  • Identification of gene mutation in patients with osteogenesis imperfect using high resolution melting analysis.

    abstract：:Osteogenesis imperfecta (OI), a congenital bone disorder, is caused by mutations in COL1A1 and COL1A2 genes, leading to deficiency of type I collagen. The high resolution melting (HRM) analysis has been used for detecting mutations, polymorphisms and epigenetic alteration in double-stranded DNAs. This study was to eva...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep13468

    authors： Wang J,Ren X,Bai X,Zhang T,Wang Y,Li K,Li G

    更新日期：2015-08-26 00:00:00

  • Acute fluoxetine exposure alters crab anxiety-like behaviour, but not aggressiveness.

    abstract：:Aggression and responsiveness to noxious stimuli are adaptable traits that are ubiquitous throughout the animal kingdom. Like vertebrate animals, some invertebrates have been shown to exhibit anxiety-like behaviour and altered levels of aggression that are modulated by the neurotransmitter serotonin. To investigate wh...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep19850

    authors： Hamilton TJ,Kwan GT,Gallup J,Tresguerres M

    更新日期：2016-01-25 00:00:00

  • A Novel Mechanism for Nitrosative Stress Tolerance Dependent on GTP Cyclohydrolase II Activity Involved in Riboflavin Synthesis of Yeast.

    abstract：:The biological functions of nitric oxide (NO) depend on its concentration, and excessive levels of NO induce various harmful situations known as nitrosative stress. Therefore, organisms possess many kinds of strategies to regulate the intracellular NO concentration and/or to detoxify excess NO. Here, we used genetic s...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-62890-3

    authors： Anam K,Nasuno R,Takagi H

    更新日期：2020-04-07 00:00:00

  • Nuclear shape, protrusive behaviour and in vivo retention of human bone marrow mesenchymal stromal cells is controlled by Lamin-A/C expression.

    abstract：:Culture expanded mesenchymal stromal cells (MSCs) are being extensively studied for therapeutic applications, including treatment of graft-versus-host disease, osteogenesis imperfecta and for enhancing engraftment of hematopoietic stem cells after transplantation. Thus far, clinical trials have shown that the therapeu...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-50955-x

    authors： Dorland YL,Cornelissen AS,Kuijk C,Tol S,Hoogenboezem M,van Buul JD,Nolte MA,Voermans C,Huveneers S

    更新日期：2019-10-07 00:00:00

  • Herd-level bovine tuberculosis risk factors: assessing the role of low-level badger population disturbance.

    abstract：:Bovine TB (bTB) is endemic in Irish cattle and has eluded eradication despite considerable expenditure, amid debate over the relative roles of badgers and cattle in disease transmission. Using a comprehensive dataset from Northern Ireland (>10,000 km(2); 29,513 cattle herds), we investigated interactions between host ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep13062

    authors： Wright DM,Reid N,Ian Montgomery W,Allen AR,Skuce RA,Kao RR

    更新日期：2015-08-17 00:00:00

  • Prospects of activity limitations among older adults in 23 low and middle income countries.

    abstract：:Increasing life expectancy and a growing share of older people around the world spotlight the issue of health during additional years of life. Research on trends of proportions of older people with activity limitations for low and middle income countries is sparse. We use data from the World Health Survey and the UN W...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-67166-4

    authors： Weber D,Scherbov S

    更新日期：2020-06-26 00:00:00

  • SB772077B, A New Rho Kinase Inhibitor Enhances Aqueous Humour Outflow Facility in Human Eyes.

    abstract：:We investigated the effect of a new Rho kinase inhibitor, SB772077B (SB77) on aqueous outflow facility (OF) in human eyes using human organ-cultured anterior segment (HOCAS). IOP was monitored for 24 h post-treatment with either SB77 (0.1/10/50 µM) or vehicle after a stable baseline pressure. The hydrodynamic pattern ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-33932-8

    authors： Ashwinbalaji S,Senthilkumari S,Gowripriya C,Krishnadas S,Gabelt BAT,Kaufman PL,Muthukkaruppan V

    更新日期：2018-10-19 00:00:00

  • Two-photon polymerisation 3D printed freeform micro-optics for optical coherence tomography fibre probes.

    abstract：:Miniaturised optical coherence tomography (OCT) fibre-optic probes have enabled high-resolution cross-sectional imaging deep within the body. However, existing OCT fibre-optic probe fabrication methods cannot generate miniaturised freeform optics, which limits our ability to fabricate probes with both complex optical ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-32407-0

    authors： Li J,Fejes P,Lorenser D,Quirk BC,Noble PB,Kirk RW,Orth A,Wood FM,Gibson BC,Sampson DD,McLaughlin RA

    更新日期：2018-10-04 00:00:00

  • New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation.

    abstract：:The development and maturation of cortical circuits relies on the coordinated actions of long and short range axonal guidance cues. In this regard, the class 3 semaphorins and their receptors have been seen to be involved in the development and maturation of the hippocampal connections. However, although the role of m...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-19794-0

    authors： Mata A,Gil V,Pérez-Clausell J,Dasilva M,González-Calixto MC,Soriano E,García-Verdugo JM,Sanchez-Vives MV,Del Río JA

    更新日期：2018-01-22 00:00:00

  • Identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual's data.

    abstract：:The threshold size for enlarged abdominal lymph nodes (E-ALNs), a common pediatric disorder, has yet to be standardized. According to the maximum short-axis diameter, this study divided ALNs into Grade A (≥ 10 mm), Grade B (8-10 mm), Grade C (5-8 mm), and Grade D (< 5 mm, normal). To identify the threshold size for E-...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-021-81339-9

    authors： He L,Sun Y,Huang G

    更新日期：2021-01-19 00:00:00

  • Author Correction: Nitric oxide mediated inhibition of antigen presentation from DCs to CD4+ T cells in cancer and measurement of STAT1 nitration.

    abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper. ...

    journal_title：Scientific reports

    pub_type： 已发布勘误

    doi：10.1038/s41598-018-21306-z

    authors： Markowitz J,Wang J,Vangundy Z,You J,Yildiz V,Yu L,Foote IP,Branson OE,Stiff AR,Brooks TR,Biesiadecki B,Olencki T,Tridandapani S,Freitas MA,Papenfuss T,Phelps MA,Carson WE

    更新日期：2018-03-06 00:00:00

  • Design, transform and control of optical field in discrete optical system: an example.

    abstract：:A discrete optical system can broaden the spatial distribution of the input light through optical coupling in array waveguides, just like diffraction in continuous media. Here, we theoretically demonstrate several kinds of control methods of optical field propagation in a discrete optical system, which is composed of ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-05414-w

    authors： Deng H,Yuan Y,Yuan L

    更新日期：2017-07-12 00:00:00

  • Activation-induced cytidine deaminase targets SUV4-20-mediated histone H4K20 trimethylation to class-switch recombination sites.

    abstract：:Activation-induced cytidine deaminase (AID) triggers antibody diversification in B cells by catalysing deamination and subsequently mutating immunoglobulin (Ig) genes. Association of AID with RNA Pol II and occurrence of epigenetic changes during Ig gene diversification suggest participation of AID in epigenetic regul...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-07380-9

    authors： Rodríguez-Cortez VC,Martínez-Redondo P,Català-Moll F,Rodríguez-Ubreva J,Garcia-Gomez A,Poorani-Subramani G,Ciudad L,Hernando H,Pérez-García A,Company C,Urquiza JM,Ramiro AR,Di Noia JM,Vaquero A,Ballestar E

    更新日期：2017-08-08 00:00:00

  • Anti-apoptotic activity of ETB receptor agonist, IRL-1620, protects neural cells in rats with cerebral ischemia.

    abstract：:Endothelin-B receptor agonist, IRL-1620, provides significant neuroprotection following cerebral ischemia in rats. Whether this neuroprotection is due to inhibition of apoptosis is unknown. IRL-1620-treated rats following permanent middle cerebral artery occlusion (MCAO) showed significant improvement in neurological ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-46203-x

    authors： Briyal S,Ranjan AK,Hornick MG,Puppala AK,Luu T,Gulati A

    更新日期：2019-07-18 00:00:00

  • Lysophosphatidic acids and their substrate lysophospholipids in cerebrospinal fluid as objective biomarkers for evaluating the severity of lumbar spinal stenosis.

    abstract：:Lysophospholipids (LPLs) are known to have potentially important roles in the initiation and maintenance of neuropathic pain in animal models. This study investigated the association between the clinical severity of lumbar spinal stenosis (LSS) and the cerebrospinal fluid (CSF) levels of LPLs, using human samples. We ...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-45742-7

    authors： Hayakawa K,Kurano M,Ohya J,Oichi T,Kano K,Nishikawa M,Uranbileg B,Kuwajima K,Sumitani M,Tanaka S,Aoki J,Yatomi Y,Chikuda H

    更新日期：2019-06-24 00:00:00

  • Screening of Parkinsonian subtle fine-motor impairment from touchscreen typing via deep learning.

    abstract：:Fine-motor impairment (FMI) is progressively expressed in early Parkinson's Disease (PD) patients and is now known to be evident in the immediate prodromal stage of the condition. The clinical techniques for detecting FMI may not be robust enough and here, we show that the subtle FMI of early PD patients can be effect...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-020-69369-1

    authors： Iakovakis D,Chaudhuri KR,Klingelhoefer L,Bostantjopoulou S,Katsarou Z,Trivedi D,Reichmann H,Hadjidimitriou S,Charisis V,Hadjileontiadis LJ

    更新日期：2020-07-28 00:00:00

  • A pilot-scale forward osmosis membrane system for concentrating low-strength municipal wastewater: performance and implications.

    abstract：:Recovery of nutrients and energy from municipal wastewater has attracted much attention in recent years; however, its efficiency is significantly limited by the low-strength properties of municipal wastewater. Herein, we report a pilot-scale forward osmosis (FO) system using a spiral-wound membrane module to concentra...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep21653

    authors： Wang Z,Zheng J,Tang J,Wang X,Wu Z

    更新日期：2016-02-22 00:00:00

  • Association between newborn screening analytes and hypoxic ischemic encephalopathy.

    abstract：:Hypoxic ischemic encephalopathy (HIE) is a major cause of neonatal mortality and morbidity. Our study sought to examine whether patterns of newborn screening analytes differed between infants with and without neonatal HIE in order to identify opportunities for potential use of these analytes for diagnosis in routine c...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-51919-x

    authors： Wilson LA,Fell DB,Hawken S,Wong CA,Murphy MSQ,Little J,Potter BK,Walker M,Lacaze-Masmonteil T,Juul S,Chakraborty P,Wilson K

    更新日期：2019-10-31 00:00:00

  • Switching of spins and entanglement in surface-supported antiferromagnetic chains.

    abstract：:Previous experimental studies discovered universal growth of chains and nanowires of various chemical elements on a corrugated molecular network of Cu3N on the Cu(110). Herein, performing combined ab initio and quantum Hamiltonian studies we demonstrate that such chains can be used for a fast spin switching and entang...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-02972-x

    authors： Sivkov IN,Bazhanov DI,Stepanyuk VS

    更新日期：2017-06-05 00:00:00

  • Enhanced microbubble contrast agent oscillation following 250 kHz insonation.

    abstract：:Microbubble contrast agents are widely used in ultrasound imaging and therapy, typically with transmission center frequencies in the MHz range. Currently, an ultrasound center frequency near 250 kHz is proposed for clinical trials in which ultrasound combined with microbubble contrast agents is applied to open the blo...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-018-34494-5

    authors： Ilovitsh T,Ilovitsh A,Foiret J,Caskey CF,Kusunose J,Fite BZ,Zhang H,Mahakian LM,Tam S,Butts-Pauly K,Qin S,Ferrara KW

    更新日期：2018-11-05 00:00:00

  • Albino T-DNA tomato mutant reveals a key function of 1-deoxy-D-xylulose-5-phosphate synthase (DXS1) in plant development and survival.

    abstract：:Photosynthetic activity is indispensable for plant growth and survival and it depends on the synthesis of plastidial isoprenoids as chlorophylls and carotenoids. In the non-mevalonate pathway (MEP), the 1-deoxy-D-xylulose-5-phosphate synthase 1 (DXS1) enzyme has been postulated to catalyze the rate-limiting step in th...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/srep45333

    authors： García-Alcázar M,Giménez E,Pineda B,Capel C,García-Sogo B,Sánchez S,Yuste-Lisbona FJ,Angosto T,Capel J,Moreno V,Lozano R

    更新日期：2017-03-28 00:00:00

  • Screening Specific Biomarkers of Herbs Using a Metabolomics Approach: A Case Study of Panax ginseng.

    abstract：:Medicinal herbs belonging to the same genus are always easily confused due to their extremely similar morphology and metabolites. Previously, to differentiate them, inherently specific biomarkers were screened out via intuitive comparison of their metabolite profiles. Unfortunately, the selected biomarkers have worked...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-04712-7

    authors： Wang HP,Liu Y,Chen C,Xiao HB

    更新日期：2017-07-04 00:00:00

  • Reduced Graphene Oxide-Gold Nanoparticle Nanoframework as a Highly Selective Separation Material for Aflatoxins.

    abstract：:Graphene-based materials have been studied in many applications, owing to the excellent electrical, mechanical, and thermal properties of graphene. In the current study, an environmentally friendly approach to the preparation of a reduced graphene oxide-gold nanoparticle (rGO-AuNP) nanocomposite was developed by using...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-017-15210-1

    authors： Guo W,Wu L,Fan K,Nie D,He W,Yang J,Zhao Z,Han Z

    更新日期：2017-11-03 00:00:00

  • Author Correction: Androgen receptor is a potential novel prognostic marker and oncogenic target in osteosarcoma with dependence on CDK11.

    abstract：:A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper. ...

    journal_title：Scientific reports

    pub_type： 已发布勘误

    doi：10.1038/s41598-018-30644-x

    authors： Liao Y,Sassi S,Halvorsen S,Feng Y,Shen J,Gao Y,Cote G,Choy E,Harmon D,Mankin H,Hornicek F,Duan Z

    更新日期：2018-08-09 00:00:00

  • Use of a Lymphatic Drug Delivery System and Sonoporation to Target Malignant Metastatic Breast Cancer Cells Proliferating in the Marginal Sinuses.

    abstract：:Lymph node (LN) metastasis through the lymphatic network is a major route for cancer dissemination. Tumor cells reach the marginal sinuses of LNs via afferent lymphatic vessels (LVs) and form metastatic lesions that lead to distant metastasis. Thus, targeting of metastatic cells in the marginal sinuses could improve c...

    journal_title：Scientific reports

    pub_type： 杂志文章

    doi：10.1038/s41598-019-49386-5

    authors： Kato S,Shirai Y,Sakamoto M,Mori S,Kodama T

    更新日期：2019-09-13 00:00:00