Abstract:
:During an avian mass mortality event investigation at the National Fish and Wildlife Forensic Laboratory in Ashland, OR, imidacloprid became an insecticide of concern. A qualitative analytical toxicology screen of seeds, plucks (tongue, esophagus, and trachea), and ventricular contents was requested. A method for the extraction and qualitative analysis of the insecticide in animal tissues was therefore developed. The procedure relies on a combined Food Emergency Response Network (FERN) and QuEChERS (Quick, Easy, Cheap, Effective, Rugged, and Safe) approach to sample extraction followed by qualitative analysis by gas chromatography-tandem mass spectrometry. Since imidacloprid is not amenable to the conditions of gas chromatography, a trimethylsilyl derivative was created and characterized. Proposed mechanisms for the creation of this derivative and its mass spectrum are described. The imidacloprid-trimethylsilyl (TMS) derivative was detected in all samples submitted.
journal_name
Toxicol Mech Methodsjournal_title
Toxicology mechanisms and methodsauthors
Buchweitz JP,Viner TC,Lehner AFdoi
10.1080/15376516.2019.1616344subject
Has Abstractpub_date
2019-09-01 00:00:00pages
511-517issue
7eissn
1537-6516issn
1537-6524journal_volume
29pub_type
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