Membrane Stabilizer Medications in the Treatment of Chronic Neuropathic Pain: a Comprehensive Review.

Abstract:

PURPOSE OF REVIEW:Neuropathic pain is often debilitating, severely limiting the daily lives of patients who are affected. Typically, neuropathic pain is difficult to manage and, as a result, leads to progression into a chronic condition that is, in many instances, refractory to medical management. RECENT FINDINGS:Gabapentinoids, belonging to the calcium channel blocking class of drugs, have shown good efficacy in the management of chronic pain and are thus commonly utilized as first-line therapy. Various sodium channel blocking drugs, belonging to the categories of anticonvulsants and local anesthetics, have demonstrated varying degrees of efficacy in the in the treatment of neurogenic pain. Though there is limited medical literature as to efficacy of any one drug, individualized multimodal therapy can provide significant analgesia to patients with chronic neuropathic pain.

journal_name

Curr Pain Headache Rep

authors

Viswanath O,Urits I,Jones MR,Peck JM,Kochanski J,Hasegawa M,Anyama B,Kaye AD

doi

10.1007/s11916-019-0774-0

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

37

issue

6

eissn

1531-3433

issn

1534-3081

pii

10.1007/s11916-019-0774-0

journal_volume

23

pub_type

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