Flavonoids and Insulin-Resistance: From Molecular Evidences to Clinical Trials.

Abstract:

:Insulin-resistance is one of the main factors responsible for the onset and progression of Metabolic Syndrome (MetS). Among all polyphenols, the effects of flavonoids and their main food sources on insulin sensitivity have been widely evaluated in molecular and clinical studies. The aim of this review is to analyse the data observed in vitro, in vivo and in clinical trials concerning the effects of flavonoids on insulin resistance and to determine the molecular mechanisms with which flavonoids interact with insulin signaling.

journal_name

Int J Mol Sci

authors

Russo B,Picconi F,Malandrucco I,Frontoni S

doi

10.3390/ijms20092061

subject

Has Abstract

pub_date

2019-04-26 00:00:00

issue

9

issn

1422-0067

pii

ijms20092061

journal_volume

20

pub_type

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