Primary intracranial leiomyosarcoma in an immunocompetent patient: Case report with emphasis on imaging features.

Abstract:

RATIONALE:Primary intracranial leiomyosarcoma (LMS) is an extremely rare tumor in the central nervous system (CNS), and usually seen in immunocompromised individuals. Only a few cases of primary intracranial LMS have been documented in the literature and no study focused on their MRI findings. We reported a case of primary intracranial leiomyosarcoma in a immunocompetent patient and review its imaging features. PATIENT CONCERNS:A 20-year-old female was admitted to our hospital, complaining with nausea, weight loss and progressive headache in recent 2 years. DIAGNOSIS:The magnetic resonance imaging scan of the brain revealed a large well-defined extra-cerebral mass adherent to left temporal meninges. The mass was iso-intense on T1-weighted images (T1WI), lightly iso to hypointense on T2-weighted images (T2WI) and enhanced uniformly with contrast medium. The preoperative diagnosis is meningioma. INTERVENTIONS:A left craniotomy was performed for the complete resection of the mass. OUTCOMES:The lesion was diagnosed via surgical histopathology and immunochemistry as leiomyosarcoma. No evidence of recurrence and complications were found in the following 13 months. LESSIONS:Primary intracranial leiomyosarcoma which has some special MR imaging features should be considered in the differential diagnosis of intracranial tumor.

journal_name

Medicine (Baltimore)

journal_title

Medicine

authors

Li XL,Ren J,Niu RN,Jiang X,Xu GH,Zhou P,Cheng ZZ

doi

10.1097/MD.0000000000015269

subject

Has Abstract

pub_date

2019-04-01 00:00:00

pages

e15269

issue

17

eissn

0025-7974

issn

1536-5964

pii

00005792-201904260-00031

journal_volume

98

pub_type

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