Abstract:
:Breastfeeding is a major determinant of human health. Breast milk is not sterile and ecological large-scale sequencing methods have revealed an unsuspected microbial diversity that plays an important role. However, microbiological analysis at the species level has been neglected while it is a prerequisite before understanding which microbe is associated with symbiosis or dysbiosis, and health or disease. We review the currently known bacterial repertoire from the human breast and milk microbiota using a semiautomated strategy. Total 242 articles from 38 countries, 11,124 women and 15,489 samples were included. Total 820 species were identified mainly composed of Proteobacteria and Firmicutes. We report variations according to the analytical method (culture or molecular method), the anatomical site (breast, colostrum or milk) and the infectious status (healthy control, mastitis, breast abscess, neonatal infection). In addition, we compared it with the other human repertoires. Finally, we discuss its putative origin and role in health and disease.
journal_name
Future Microbioljournal_title
Future microbiologyauthors
Togo A,Dufour JC,Lagier JC,Dubourg G,Raoult D,Million Mdoi
10.2217/fmb-2018-0317subject
Has Abstractpub_date
2019-05-01 00:00:00pages
623-641eissn
1746-0913issn
1746-0921journal_volume
14pub_type
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