Repertoire of human breast and milk microbiota: a systematic review.

Abstract:

:Breastfeeding is a major determinant of human health. Breast milk is not sterile and ecological large-scale sequencing methods have revealed an unsuspected microbial diversity that plays an important role. However, microbiological analysis at the species level has been neglected while it is a prerequisite before understanding which microbe is associated with symbiosis or dysbiosis, and health or disease. We review the currently known bacterial repertoire from the human breast and milk microbiota using a semiautomated strategy. Total 242 articles from 38 countries, 11,124 women and 15,489 samples were included. Total 820 species were identified mainly composed of Proteobacteria and Firmicutes. We report variations according to the analytical method (culture or molecular method), the anatomical site (breast, colostrum or milk) and the infectious status (healthy control, mastitis, breast abscess, neonatal infection). In addition, we compared it with the other human repertoires. Finally, we discuss its putative origin and role in health and disease.

journal_name

Future Microbiol

journal_title

Future microbiology

authors

Togo A,Dufour JC,Lagier JC,Dubourg G,Raoult D,Million M

doi

10.2217/fmb-2018-0317

subject

Has Abstract

pub_date

2019-05-01 00:00:00

pages

623-641

eissn

1746-0913

issn

1746-0921

journal_volume

14

pub_type

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