Curcumin ameliorates atherosclerosis through upregulation of miR-126.

abstract：:Chick embryo fibroblasts were maintained at confluency for up to 35 days in medium containing 0.5% or 0.75% fetal bovine serum or 2.5% or 5.0% horse serum. At weekly intervals cells were subcultured and serially propagated in medium containing 10% FBS until their replicative lifespans were completed. The results showe...

journal_title：Journal of cellular physiology

authors： Nielsen PJ,Ryan JM

更新日期：1981-06-01 00:00:00

abstract：:The vascular isoform of ATP-sensitive K(+) (KATP ) channels regulates blood flow to all organs. The KATP channel is strongly inhibited by reactive oxygen and carbonyl species produced in diabetic tissue inflammation. To address how such channel inhibition impacts vascular regulation as well as tissue viability, we per...

journal_title：Journal of cellular physiology

authors： Li SS,Cui N,Yang Y,Trower TC,Wei YM,Wu Y,Zhang S,Jin X,Jiang C

更新日期：2015-12-01 00:00:00

abstract：:The statins (including mevastatin and lovastatin) are a widely prescribed class of serum-cholesterol lowering drugs that function by inhibiting 3-hydroxymethylglutaryl coenzyme A (HMG CoA) reductase activity and cellular sterol synthesis. Statins are also widely being appreciated for their inhibitory effects upon infl...

journal_title：Journal of cellular physiology

authors： Arikan MC,Shapiro SD,Mariani TJ

更新日期：2005-07-01 00:00:00

abstract：:We determined the synthesis and secretion of glycosaminoglycans by three distinct preparations of mouse cultured thymic epithelial cells. These comprised primary cultures of thymic nurse cells (TNCs), which are normally located within the cortex of the thymic lobules, as well as two murine thymic epithelial cells, bea...

journal_title：Journal of cellular physiology

authors： Werneck CC,Cruz MS,Silva LC,Villa-Verde DM,Savino W,Mourão PA

更新日期：2000-10-01 00:00:00

abstract：:The objective of this study was to establish whether human recombinant tumor necrosis factor (TNF) can significantly stimulate the proliferation of some tumor cells. Treatment with TNF had little or no effect on the growth of human tumor cells and murine NIH/3T3 cells cultured in medium with high serum concentration. ...

journal_title：Journal of cellular physiology

authors： Kirstein M,Baglioni C

更新日期：1988-03-01 00:00:00

abstract：:The mechanism(s) by which heparin influences the biological activities of acidic and basic fibroblast growth factors (aFGF and bFGF) is not completely understood. One mechanism by which heparin could alter the biological activities of aFGF and bFGF is by altering their biological half-lives. We investigated the possib...

journal_title：Journal of cellular physiology

authors： Damon DH,Lobb RR,D'Amore PA,Wagner JA

更新日期：1989-02-01 00:00:00

abstract：:A mouse mammary epithelial cell line, NMuMG, exhibits a low capacity to grow in semisolid medium as colonies and it is not tumorigenic in nude mice. In contrast, NMuMG cells which have been transformed by an activated c-Harvey ras proto-oncogene, NMuMG/rasH, or by the polyoma middle T-transforming gene, NMuMG/pyt, are...

journal_title：Journal of cellular physiology

authors： Salomon DS,Perroteau I,Kidwell WR,Tam J,Derynck R

更新日期：1987-03-01 00:00:00

abstract：:The kinetic properties of partially purified ribonucleotide reductase from Chinese hamster ovary cells have been investigated. Double reciprocal plots of velocity against substrate concentration were found to be linear for three the substrates tested, and yielded apparent Km values of 0.12 mM for CDP, 0.14 mM for ADP ...

journal_title：Journal of cellular physiology

authors： Lewis WH,Wright JA

更新日期：1978-10-01 00:00:00

abstract：:The interaction of basic FGF (bFGF) with heparin, heparan sulfate and related sugars can potentiate or antagonize bFGF activity, depending on the size of the saccharide used. Oligosaccharides based on heparin structures, as small as six sugar residues, have been demonstrated to bind to bFGF and block its activity, whi...

journal_title：Journal of cellular physiology

authors： Foxall C,Wei Z,Schaefer ME,Casabonne M,Fugedi P,Peto C,Castellot JJ Jr,Brandley BK

更新日期：1996-09-01 00:00:00

abstract：:Adsorption of Sendai virus at high multiplicity (500-1,000 HAU/10(6) cells) to HeLa cells grown in monolayers causes immediate changes in the ion barrier of the cell membrane, as well as changes in the morphology of the virus-treated cells. Within minutes of adsorption the cells begin to lose potassium and an extensiv...

journal_title：Journal of cellular physiology

authors： Spiegelstein PF,Haimsohn M,Gitelman J,Kohn A

更新日期：1978-05-01 00:00:00

abstract：:Beta-arrestins are scaffolding proteins implicated as negative regulators of TLR4 signaling in macrophages and fibroblasts. Unexpectedly, we found that beta-arrestin-1 (beta-arr-1) and -2 knockout (KO) mice are protected from TLR4-mediated endotoxic shock and lethality. To identify the potential mechanisms involved, w...

journal_title：Journal of cellular physiology

authors： Porter KJ,Gonipeta B,Parvataneni S,Appledorn DM,Patial S,Sharma D,Gangur V,Amalfitano A,Parameswaran N

更新日期：2010-11-01 00:00:00

abstract：:We examined the expression of the estrogen and epidermal growth factor (EGF) receptors in a drug-resistant subline of MCF-7 cells in order to study potential alterations in hormone dependence or in the growth factor pathway that could be related to the development of drug resistance in human breast cancer. The drug-re...

journal_title：Journal of cellular physiology

authors： Dickstein B,Valverius EM,Wosikowski K,Saceda M,Pearson JW,Martin MB,Bates SE

更新日期：1993-10-01 00:00:00

abstract：:Vero (African green monkey kidney) cells grown in tissue culture monolayer were sensitive to Clostridium perfringens enterotoxin. Within 30 minutes of exposure to the enterotoxin gross morphological damage was observed and within 40 minutes approximately 75% of the cells had detached. Nearly half of the cells were non...

journal_title：Journal of cellular physiology

authors： McClane BA,McDonel JL

更新日期：1979-05-01 00:00:00

abstract：:The Toll and Toll-like receptor signaling pathways are evolutionarily conserved pathways that regulate innate immunity in insects and mammals. While efforts have been made to clarify the signal transduction events that occur during infection, much less is known about the components that maintain immune quiescence. Her...

journal_title：Journal of cellular physiology

authors： Zhou B,Yun EY,Ray L,You J,Ip YT,Lin X

更新日期：2014-04-01 00:00:00

abstract：:Generation of reactive oxygen species (ROS) is a common event in the pathogenesis of acute lung injury. Endothelial cells may be both a target and a source of the ROS. Exposure of bovine pulmonary endothelial cells (BPAEC) to lipopolysaccharide (LPS) has been shown to result in intracellular generation of both ROS and...

journal_title：Journal of cellular physiology

authors： Mitchell J,Jiang H,Berry L,Meyrick B

更新日期：1996-11-01 00:00:00

abstract：:Adult bone marrow mesenchymal stromal cells (BMSCs) can easily be differentiated into a variety of cells. In vivo transplantation of BMSCs-differentiated cells has had limited success, suggesting that these cells may not be fully compatible with the cells they are intended to replace in vivo. We investigated the struc...

journal_title：Journal of cellular physiology

authors： Gruia AT,Suciu M,Barbu-Tudoran L,Azghadi SM,Cristea MI,Nica DV,Vaduva A,Muntean D,Mic AA,Mic FA

更新日期：2016-04-01 00:00:00

abstract：:Human skin fibroblasts contracted fibrin gels in a time- and cell-dependent manner. Under optimal conditions, gel contraction amounted to more than 50% in 2 hr. Fibronectin did not promote contraction, and fibrinolysis was not required for contraction, although gels contracted without serum or aprotinin were lysed. Be...

journal_title：Journal of cellular physiology

authors： Tuan TL,Grinnell F

更新日期：1989-09-01 00:00:00

abstract：:rac-1-O-Myristoyl-2-O-acetylglycerol, rac-1-O-palmitoyl-2-O-acetylglycerol, and rac-1-O-oleoyl-2-O-acetylglycerol acted like phorbol myristate acetate and mezerein in stimulating human neutrophil aggregation. Responses to these agents were equally influenced by cytochalasin B, extracellular calcium and magnesium, arac...

journal_title：Journal of cellular physiology

authors： O'Flaherty JT,Schmitt JD,Wykle RL,Redman JF Jr,McCall CE

更新日期：1985-11-01 00:00:00

abstract：:Glucocorticoid-induced osteonecrosis of the femoral head (GIOFH) is one of the most common complications of glucocorticoid administration. By chelating Fe2+ , desferoxamine (DFO) was reported to be able to activate the HIF-1α/VEGF pathway and promote angiogenesis. In the present study, we examined whether DFO administ...

journal_title：Journal of cellular physiology

authors： Jing X,Du T,Yang X,Zhang W,Wang G,Liu X,Li T,Jiang Z

更新日期：2020-12-01 00:00:00

abstract：:These studies describe a liquid suspension culture system for normal myeloid cells derived from human foetal liver. A simple one-step fractionation procedure was employed to obtain a cell population capable of expanding into all stages of myeloid differentiation, including committed myeloid progenitor cells (GM-CFC). ...

journal_title：Journal of cellular physiology

authors： Toksoz D,Brown G

更新日期：1984-05-01 00:00:00

abstract：:Both the Na+-dependent glucose cotransporter (SGLT1) and the cystic fibrosis transmembrane conductance regulator (CFTR) modulate Na+ and fluid movement, although in opposite directions. Yet few studies have investigated a possible interrelationship between these two transporters. By using the Caco-2 human colon carcin...

journal_title：Journal of cellular physiology

authors： Mailleau C,Capeau J,Brahimi-Horn MC

更新日期：1998-09-01 00:00:00

abstract：:The increased levels of c-Myc protein observed previously in an ovarian carcinoma cell line stably transfected to express HER2 has suggested a role for the HER2 pathway in c-Myc expression. Analysis of HER2-transfected cells stimulated with heregulin beta1 (HRG) revealed increased c-Myc protein levels but not a corres...

journal_title：Journal of cellular physiology

authors： Galmozzi E,Casalini P,Iorio MV,Casati B,Olgiati C,Ménard S

更新日期：2004-07-01 00:00:00

abstract：:Wnt and TGF-β signaling pathways participate in regulating a variety of cell fates during organogenesis, including tooth development. Despite well-documented, the specific mechanisms, especially how these two pathways act coordinately in regulating enamel development, remain unknown. In this study, we identified Glyco...

journal_title：Journal of cellular physiology

authors： Yang Y,Li Z,Chen G,Li J,Li H,Yu M,Zhang W,Guo W,Tian W

更新日期：2018-07-01 00:00:00

abstract：:The cells responsible for the long-term in vitro generation of murine mast cells have been examined. Sequential analysis of all colony types obtained from cultures of spleen or bone marrow cells showed that only colonies derived from multipotential cells (mixed-erythroid colonies) or mast cell progenitors, contained c...

journal_title：Journal of cellular physiology

authors： Li CL,Johnson GR

更新日期：1984-10-01 00:00:00

abstract：:Cytoplasmic poly-A containing RNA, synthesized by cultured chick embryo cells, was examined during growth in 5-bromodeoxyuridine. The kinetics of 3H-adenosine incorporation into this species of RNA, when compared to the rest of the cytoplasmic RNA, and to control cells, indicates that the rate of synthesis of this RNA...

journal_title：Journal of cellular physiology

authors： Pawlowski PJ

更新日期：1976-09-01 00:00:00

abstract：:The mechanism of zinc (Zn) uptake by microvillous membrane vesicles prepared from human term placenta has been studied. The uptake was complex, with two processes being identified. In the first process, uptake was rapid, reaching equilibrium within 2 min, and was temperature dependent, with a Q10 of 1.5. Equilibrium Z...

journal_title：Journal of cellular physiology

authors： Aslam N,McArdle HJ

更新日期：1992-06-01 00:00:00

abstract：:The percentage of T and B lymphocytes expressing a distinct cytoplasmic aggregate enriched in spectrin, ankyrin, and in several other proteins including protein kinase C greatly increases following various activation protocols. Members of the 70 kDa family of heat shock proteins (hsp70) temporarily bind to and stabili...

journal_title：Journal of cellular physiology

authors： Di YP,Repasky E,Laszlo A,Calderwood S,Subjeck J

更新日期：1995-11-01 00:00:00

abstract：:Cardiac hypertrophy is the main cause of heart failure and sudden death in patients. But the pathogenesis is unclear. Angiotensin II may contribute to cardiac hypertrophy in response to pressure overload. In angiotensin II-treated cardiomyocytes, there is a larger cross-sectional area, more apoptosis cells, and a redu...

journal_title：Journal of cellular physiology

authors： Li R,Wang X,Wu S,Wu Y,Chen H,Xin J,Li H,Lan J,Xue K,Li X,Zhuo C,He J,Tang CS,Jiang W

更新日期：2019-08-01 00:00:00

abstract：:Therapeutic application of stem cells and oncolytic viruses in cancer treatment has rapidly increased in the last decade. Oncolytic viruses are considered as a new class of anticancer agents because of their ability to selectively infect and destroy cancer cells. Furthermore, regarding the specific migratory capacity ...

journal_title：Journal of cellular physiology

authors： Zendedel E,Atkin SL,Sahebkar A

更新日期：2019-02-15 00:00:00

abstract：:We investigated gene expression profiles of vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) in differentiated and non-differentiated retinal pigment epithelial (RPE) cells during oxidative stress. Human RPE cells were grown in culture on laminin-coated flasks to obtain differenti...

journal_title：Journal of cellular physiology

authors： Ohno-Matsui K,Morita I,Tombran-Tink J,Mrazek D,Onodera M,Uetama T,Hayano M,Murota SI,Mochizuki M

更新日期：2001-12-01 00:00:00