Abstract:
RATIONALE:Small-cell lung cancer (SCLC) is a common pathological type of lung cancer, but appendiceal metastasis of SCLC was rare. At present, clinical studies on the maintenance therapy of SCLC have not reached a significant conclusion. PATIENT CONCERNS:We reported on a 52-year-old man who diagnosed as extensive stage SCLC with abdominal pain for 2 months, aggravated for 2 days. DIAGNOSES:The patient was diagnosed with extensive-stage SCLC, relapsed with appendix metastasis after treatment by emergency abdominal surgery. INTERVENTIONS:The patient received systemic treatments, including surgery, bevacizumab in combination with chemotherapy and bevacizumab alone was continued as maintenance therapy. OUTCOMES:The patient had an overall survival would more than 23 months, and he gained another 8 months of progression-free survival after first-line radiochemotherapy. LESSONS:Although SCLC appendix metastasis is rare, continuous anti-angiogenic therapy combined with bevacizumab maintenance therapy after surgical treatment can prolong survival.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Xue P,Wang N,Mao Y,Zhu Sdoi
10.1097/MD.0000000000015333subject
Has Abstractpub_date
2019-04-01 00:00:00pages
e15333issue
16eissn
0025-7974issn
1536-5964pii
00005792-201904190-00071journal_volume
98pub_type
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