Abstract:
:The initiation of T lymphocyte responses within secondary lymphoid organs involves interactions with different subsets of dendritic cells (DCs). Recent studies have revealed the complexity of microanatomical organization within lymphoid organs. Exactly how T cells and DCs locate each other and the type of cellular interactions required for optimal priming of effector and memory T cell responses are beginning to be unraveled. Here we review advances in our understanding of how T cell priming is choreographed during infections, highlight the importance of cell positioning in this process and discuss how a spectrum of cellular interactions shapes T cell activation and differentiation.
journal_name
Immunol Revjournal_title
Immunological reviewsauthors
Ugur M,Mueller SNdoi
10.1111/imr.12753subject
Has Abstractpub_date
2019-05-01 00:00:00pages
115-128issue
1eissn
0105-2896issn
1600-065Xjournal_volume
289pub_type
杂志文章,评审abstract::Immunologists working in the field of autoimmunity tend to concentrate all their efforts on the elucidation of possible malfunctions of the immune system, particularly pathologic changes of immune regulation. Also in the OS model various groups of investigators emphasized this approach, although it was already clear e...
journal_title:Immunological reviews
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journal_title:Immunological reviews
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journal_title:Immunological reviews
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journal_title:Immunological reviews
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journal_title:Immunological reviews
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更新日期:2006-06-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:1999-02-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2000-08-01 00:00:00
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journal_title:Immunological reviews
pub_type: 杂志文章,评审
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更新日期:1984-10-01 00:00:00
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journal_title:Immunological reviews
pub_type: 杂志文章,评审
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更新日期:1996-10-01 00:00:00
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journal_title:Immunological reviews
pub_type: 杂志文章,评审
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更新日期:2001-06-01 00:00:00
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更新日期:2016-05-01 00:00:00
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更新日期:2012-11-01 00:00:00
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journal_title:Immunological reviews
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更新日期:2007-08-01 00:00:00
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更新日期:2011-05-01 00:00:00
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更新日期:2009-07-01 00:00:00
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journal_title:Immunological reviews
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journal_title:Immunological reviews
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journal_title:Immunological reviews
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更新日期:2006-02-01 00:00:00