A statistical atlas of cerebral arteries generated using multi-center MRA datasets from healthy subjects.

Abstract:

:Magnetic resonance angiography (MRA) can capture the variation of cerebral arteries with high spatial resolution. These measurements include valuable information about the morphology, geometry, and density of brain arteries, which may be useful to identify risk factors for cerebrovascular and neurological diseases at an early time point. However, this requires knowledge about the distribution and morphology of vessels in healthy subjects. The statistical arterial brain atlas described in this work is a free and public neuroimaging resource that can be used to identify vascular morphological changes. The atlas was generated based on 544 freely available multi-center MRA and T1-weighted MRI datasets. The arteries were automatically segmented in each MRA dataset and used for vessel radius quantification. The binary segmentation and vessel size information were non-linearly registered to the MNI brain atlas using the T1-weighted MRI datasets to construct atlases of artery occurrence probability, mean artery radius, and artery radius standard deviation. This public neuroimaging resource improves the understanding of the distribution and size of arteries in the healthy human brain.

journal_name

Sci Data

journal_title

Scientific data

authors

Mouches P,Forkert ND

doi

10.1038/s41597-019-0034-5

subject

Has Abstract

pub_date

2019-04-11 00:00:00

pages

29

issue

1

issn

2052-4463

pii

10.1038/s41597-019-0034-5

journal_volume

6

pub_type

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